ABSTRACT
Background: Neuroschistosomiasis is an uncommonly reported disease. Casecharacteristics: An adolescent Indian boy residing in Kenya presented with headache,visual symptoms and seizures, with MRI showing space-occupying lesions in the occipitallobe and cerebellum. Observation: Brain biopsy was diagnostic of neuro-schistosomiasis;complete recovery was seen with praziquantel and corticosteroid therapy. Message: Thiscase highlights the importance of considering epidemiology in differential diagnosis andestablishing definitive diagnosis even if it is by invasive methods
ABSTRACT
Background: Mass effect is the major cause of death in cortical venous sinus thrombosis and there is no clear cut the role of decompressive hemicraniectomy. Aims: To study the outcome of patients with large venous infarct and acutely increased intracranial pressure subjected to either conservative treatment or decompressive surgery. Materials & Methods: 20 consecutive patients admitted with moderate to large venous infarct were examined for features of raised intracranial pressure (ICP) . Cranial CT and or MRI and CT venogram or MR venogram and or cerebral DSA were examined for site of Sino venous occlusion. Results: There were 20 patients with 10 each in conservatively and surgically treated group. Cranial CT/MRI head revealed large venous infarct with midline shift and mass effect in all patients. Overall 15 of 16 survivors had good outcome at 3 months without any significant residual deficit irrespective of mode of treatment used. There is no statistical difference between medical and surgical groups in mRS 1 month, 3 months and death with p value 0.651, 0.185 and 0.474 respectively. Conclusion: Patient with large venous infarct with signs of raised intracranial pressure carries good overall outcome with timely care irrespective of conservative or surgical management.