ABSTRACT
Abstract Introduction Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine malignant cancer. It is an epidermal cancer common in the head and neck. Objectives Though there is limited number of cases described in the literature for the treatment difficult to obtain. Our purpose was to present the clinical course and treatment of four patients with MCC. Methods We conducted a retrospective analysis and obtained detailed clinical information for all 4 patients treated for MCC at the ENT Department of the SS Annunziata Hospital in Chieti, Italy, from 2013 through 2015. Results In our study, two patients presented with the tumor in a rare site (lower eyelid). All of the patients underwent surgical treatment: three patients had free excision margins and negative sentinel lymph nodes (SLNs) while 1 patient had free excision margins and positive SLNs. The latter patient underwent ipsilateral neck dissection. In another patient, the fluorodeoxyglucose positron emission topography (FDG PET)/computed tomography (CT) performed 6 months after the surgery has shown high metabolic activity in the left parotid gland, and the patient underwent total parotidectomy and a neck dissection. Conclusion Sentinel lymph node biopsy is a useful technique in small size MCCs of the head and neck. However, the parotid gland should be strictly controlled in patients with lower eyelid tumors.
ABSTRACT
Sarcomas are rare lesions of the liver and represent <1% of primary liver tumors. Embryonic sarcoma (undifferentiated) of the liver is a rare and aggressive malignant tumor that usually occurs in children with a peak incidence between 6 and 10 years. In adults, it is extremely rare with only 13 cases described in patients older than 40 years and 68 cases reported in patients older than 15 years. There is a slight predominance of females in adults. With an emphasis on morphological and immunohistochemical features, as well as on clinical data and imaging studies, we present this case report, in addition to extensive literature review on the topic.
ABSTRACT
Ameloblastoma is benign odontogenic tumor of epithelial origin which is often aggressive and it originates from remnants of the dental lamina and dental organ (odontogenic epithelium). It is generally a painless and slow growing tumor causing expansion of the cortical bone and infiltration of the soft tissues. Its incidence peak is in the third and fourth decade of life and it is most common in black individuals. The ratio of ameloblastoma of the mandible to maxilla is 5 to 1, with higher sensitivity in the mandible. Here we are reporting the case of Ameloblastoma in 36 years old female patient and we are able to find and document the typical histopathological features of Ameloblastoma.
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Objective To analyze radiological features of rare tumor of breast.Methods To analyze retrospectively radiological features of 11 cases with rare tumor, all cases were confirmed by operation or pathology. Results Among the 11 cases ,1 case was non Hodgkin lymphoma(NHL). 1 case was malignant pleomorphic adenoma. 1 case was primary squamous cell carcinoma of breast. 1 case was osteosarcoma.2 cases were lobate cystadenosarcoma. 5 cases were hamartomas.Osteosarcoma shows bone tissues in the mass. Malignant pleomorphic adenoma shows more big mass with leaning-edge and abnormal vessel.Lobate cystadenosarcoma is a low-degree malignant tumor with long history, shows big mass, cleaning-edge and big calcification in it, there was a vitellary membracnce around the mass, usually no metastasis to armpit .Hamartoma’s density is highly uneven, the area of high density likes island. Primary squamous cell carcinoma of breast and NHL have no specific X-ray features.Conclusion Rare breast tumors have no specific radiological featare.Qualitative diagnosis needs sythetical analysis.