ABSTRACT
Cerebral amyloid angiopathy is a clinical picture which is commonly seen in elderly and progressing with the deposition of amyloid in the cerebral arteries without systemic amyloidosis. We report the first case in the literature, a 71 year-old patient having an association of cerebral vein thrombosis and cerebral amyloid angiopathy presenting with recurrent cerebral hemorrhages. The cause-and-result relationship of this association of cerebral vein thrombosis and cerebral amyloid angiopathy should be investigated.
ABSTRACT
Cerebral amyloid angiopathy(CAA) is characterized by the deposition of amyloid beta-protein in the walls of small to medium-sized arteries of the leptomeninges and cerebral cortex. While often asymptomatic, CAA can develop into intracerebral hemorrhage facilitated by arterial hypertension. We report the case of a 52-year-old man with CAA and arterial hypertension who developed recurrent cerebral hemorrhages on three different occasions and in multiple non-overlapping loci over a period of nine years. Based on our findings, we recommend brain biopsies for all patients undergoing evacuation of multiple recurrence or atypical pattern intracerebral hemorrhages.