Comparison of Characteristics According to Reflux Type in Patients With Laryngopharyngeal Reflux

OBJECTIVES: To analyze laryngopharyngeal reflux (LPR) as an acidic, nonacidic, or mixed type according to 24-hour multi-channel intraluminal impedance (MII) pH monitoring and the clinical characteristics of each type. METHODS: Ninety patients were prospectively enrolled in this study. All patients underwent 24-hour MII pH monitoring as a diagnostic tool. Eighty-three patients were diagnosed with LPR. The patients were classified into three groups according to the pH of the hypopharyngeal probe: the acid reflux group, nonacid reflux group, and mixed reflux group. Subjective symptoms and objective findings were evaluated based on patients' responses to the Short Form 12 Survey (SF-12), LPR health-related quality of life (LPR-HRQOL), reflux symptom index, and reflux finding score. RESULTS: The results of each group were compared. As a result, 34 patients were classified into the nonacid reflux group and 49 into the mixed reflux group. There were no patients classified as having acid reflux alone. There was no significant difference between the two groups when comparing the reflux symptom index, reflux finding score, LPR-HRQOL, or the mental component score of the SF-12. However, the physical component score of the SF-12 was higher in the nonacid reflux group (P=0.018). The DeMeester composite score (P=0.015) and total number of LPR events (P=0.001) were lower in the nonacid reflux group than in the mixed reflux group. CONCLUSION: In conclusion, no LPR patient had only acid reflux. The nonacid reflux LPR patients showed similar clinical characteristics and findings compared to the mixed reflux group, but exhibited significantly fewer LPR episodes.

APPLICATION OF ANTI REFLUX INDWELLING NEEDLE IN THE NEURAL DEPARTMENT OF INTERNAL MEDICINE NURSING / 现代医院

Objective To explore and study the anti reflux type indwelling needle in patients with neurologi-cal department of internal medicine .Methods 100 cases of hospitalized patients with neurological department of in-ternal medicine between 2014.1~2014.12 in our hospital, were randomly divided into two groups according to the admission number .50 cases of control group with general retaining needle , and group 50 cases by anti reflux type in-dwelling needle .Retention time and related complications were compared in the two groups of patients .Results The retention time with indwelling needle time was 3.7 ±1.7d, which was significantly higher than the control group (2.8 ±1.3d), with significant difference (p0.05), but in the needle blood study group of reflux , plugging rate of Guan Fasheng were significantly lower than that of the control group , with significant difference ( p<0.05) .Conclusion Anti reflux type can effec-tively prolong the indwelling time , reduce part of indwelling needle related complications , and improve the treatment of security, which is worthy of clinical popularization and application .