ABSTRACT
China has the largest group of patients with colorectal cancer in the world,however,there are few international guidelines for the diagnosis and treatment of colorectal cancer from China,or research of high-level evidence in China.In recent years,colorectal surgery has developed rapidly in China,and great progress has been made both in clinical practice and in clinical research.But there are still many imbalances and under-regulations.In 2018,Chinese Society of Colorectal Surgery led the establishment of Chinese Colorectal Cancer Surgery Database (CCCD).The retrospective and prospective data collection coming from CCCD showed that the standardization of colorectal cancer surgery and data management needed to be improved,and the awareness of clinical research needed to be further improved.Therefore,how to carry out good clinical research and obtain high-level evidence based upon CCCD will be the great challenge for colorectal surgery in China.
ABSTRACT
China has the largest group of patients with colorectal cancer in the world, however, there are few international guidelines for the diagnosis and treatment of colorectal cancer from China, or research of high-level evidence in China. In recent years, colorectal surgery has developed rapidly in China, and great progress has been made both in clinical practice and in clinical research. But there are still many imbalances and under-regulations. In 2018, Chinese Society of Colorectal Surgery led the establishment of Chinese Colorectal Cancer Surgery Database (CCCD). The retrospective and prospective data collection coming from CCCD showed that the standardization of colorectal cancer surgery and data management needed to be improved, and the awareness of clinical research needed to be further improved. Therefore, how to carry out good clinical research and obtain high-level evidence based upon CCCD will be the great challenge for colorectal surgery in China.
ABSTRACT
Although the surgical treatment of colorectal disease progresses slowly, with the advancement of minimally invasive surgical techniques, perioperative comprehensive treatment strategies and clinical research in recent years, Chinese colorectal surgery has developed rapidly. Transanal total mesorectal excision, lateral pelvic lymph node dissection,"watch and wait"strategy for clinical complete response of neoadjuvant radiotherapy for rectal cancer, and robotic colorectal surgery are still hot topics in colorectal surgery in recent years. The construction of clinical registry database and clinical research for colorectal cancer surgery are discussed, with a view to combing the development of colorectal surgery for colleagues in the surgical field, and to seek the development of colorectal surgery in China.
ABSTRACT
Transanal total mesorectal excision (TaTME) is a new technique emerging in the field of colorectal surgery in recent years.It can solve some difficult problems of traditional open and laparoscopic surgery,and achieve good short-term clinical results.It is becoming more and more popular among colorectal surgeons in China.In the world,TaTME-related database construction,structured training,and clinical research are almost synchronized with its clinical practice.How to analyze the problems existing in the clinical practice of TaTME operation nationwide,improve the safety and effectiveness of the technology,guide its structured training,and clinical research,and build and maintain the nationwide TaTME registry database is a very effective way,but it needs a strong organizational and management framework.
ABSTRACT
Objective To assess the factors associated with occurrence of stroke in Xuzhou region on the basis of stroke registry database using data mining methods Relief F algorithm.Methods Five hundred and forty-six patients with acute cerebral infarction from June 2013 to June 2014 in Stroke Registry database and 546 healthy people at the same period in the region were chosen;their clinical data were collected and retrospectively analyzed.And the related data were collected,arranged and put into epidata database.Firstly,the data were normalized and converted to the number between 1 and 10.Relief F algorithm was used to analyze the weight of past histories and hematology index between healthy control group and stroke group.Matlab software was used to program and calculate,and the main program runs for 20 times.And then,the obtained results for each weighted average were summarized.Finally,the weight of past medical history and blood parameters in healthy control group and stroke group were obtained.Results Relief F algorithm was applied for data analysis:as compared with healthy controls,stoke group had higher weight of infarction (0.0353125) and history of drinking (0.01175),while not higher weight of history of hypertension,diabetes mellitus or transient ischemic attack;as compared with healthy controls,stoke group had higher weight of uric acid nitrogen level (0.0072),blood uric acid level (0.0071),cholesterol level (0.0067) and homocysteine level (0.0064),followed by high-density lipoprotein (0.0062),low density lipoprotein (0.0041) and triglyceride (0.0039).Conclusion Application of Relief F algorithm can excavate the closely related potential risk factors for stroke in stroke registration database.