ABSTRACT
Objective Based on the traditional Chinese medical knowledge service and sharing system, to explore the application of famous doctor Yu Ying'ao's regulating the liver method. Methods The medical records of Yu Ying'ao from the outpatient department of Chinese Academy of Sciences were used as the data source. The traditional Chinese medical knowledge service and information sharing system(V1.1.5) was applied to construct database. The regulating liver core combination of drugs, drug application mode, and combined treatment of diseases and syndromes were determined by analysis methods of frequency and association rules. Results The use of regulating liver method was often used in the treatment of irregular menstruation, cirrhosis, pain and other diseases. Differentiation of liver qi stagnation, blood stasis, liver stagnation and spleen deficiency, liver and kidney deficiency were the main TCM syndromes. Treatment included Tongluo, nourishing Yin treatment. The core drugs were Bupleurum and Rhizoma Cyperi. Conclusions The use of traditional Chinese medical service and knowledge sharing system could explore the clinical diagnosis and medication rules of regulating liver methods.
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Objective To observe the clinical efficacy of herb-partitioned moxibustion (HPM) for constipation-predominant irritable bowel syndrome (C-IBS) from the perspective of regulating liver. Method Forty C-IBS patients were randomized into a HPM group and a Western medication group. The HPM group was intervened by HPM from the perspective of regulating liver, while the Western medication group was by lactulose, both for 4 weeks. The clinical efficacies were then compared between the two groups. Result In the HPM group, 13 subjects were recovered, 3 showed markedly effective, 1 showed effective, and 3 failed; in the Western medication group, 7 subjects were cured, 3 showed markedly effective, 2 showed effective, and 8 failed. The therapeutic efficacy of the HPM group was significantly superior to that of the Western medication group (P<0.01). Conclusion HPM by regulating liver can produce a significant clinical efficacy in treating C-IBS.
ABSTRACT
Objective To study the effect of Jiajian Guishen Pill on apoptosis of rat's granulosa cells of ovary.Methods Rats' granulosa cells of ovary were cultured in vitro,stimulated with serum containing Jiajian Guishen Pill.The apoptosis rate was checked by flow cytometer and BCL-2 protein expression by immuno-fluorescence 6 hours later with the serum containing Zishen Yutai Pill and human menopausal gonadotropin(HMG)served as the control drugs.Results The apoptosis rate of the low-dosage group of serum containing Jiajian Guishen Pill was significantly lower than those of the other groups(P