ABSTRACT
Aim: To assess the role of Contrast-Enhanced Multiphasic Multidetector Computed Tomography in the evaluation of renal lesions and its potential role in differentiating benign from malignant lesions. Material and Method: This prospective study was done in the Department of Radiodiagnosis Chirayu Medical College and Hospital Bhopal. A total of 100 patients to our department with strong clinical suspicion of renal lesions and those diagnosed by ultrasonography underwent Contrast-Enhanced Multiphasic Multidetector Computed Tomographic evaluation of abdomen using 64 Multislice Spiral CT scanner from August 2015 to July 2019. Results: The majority of patients presenting with renal lesions were each of the age groups <15 years and >40 years. Most of the patients were males 57%. The most common clinical complaint was renal colic 58(46%) and hematuria. The most common pathology was calculus 35(35%) second most common pathology was congenital anomalies 23(23%). The CT accuracy for detection of benign cystic lesion in this study was 94.7%, benign lesions were 92.6%and for malignant lesions was 86.6% in the present study. Conclusion: The accuracy of Contrast-Enhanced Multiphasic Multidetector Computed Tomography in detecting and characterizing renal lesions is high and it should be considered in the imaging workup of any patient with a renal complaint
ABSTRACT
Background: Evaluation of the reasons of nephrectomy specimens in pediatric age group who presented with severe renal failure or mass lesion, which may be useful in the management of pediatric end stage renal disease. We aimed to evaluate the reasons for nephrectomy in pediatric population and to determine the frequency of various lesions. Materials and methods: It was a retrospective study of nephrectomy specimens received in our department during the period of June 2006 to June 2011 (5 years). Reasons of nephrectomy, age and sex of the patients were assessed. Results: Total 36 nephrectomy specimens were analyzed. These included 25 male children, and 11 female child. Age was ranging from 15 days to 16 years. The kidney size was small in most of the patients. The following causes were evaluated by HPE of specimens: Infantile polycystic kidney – 3, Mesoblastic nephroma – 1, Wilm’s tumor – 2, Cystic renal dysplasia – 1, Blunt injury – 4, PUJO with hydronephrosis – 15, Hydronephrosis and chronic pyelonephritis – 10. Conclusion: Nephrectomy in pediatric age group is an ultimate indication which is generally realized in neoplastic involvement of the kidney. Providing histopathological features of nephrectomy specimens and reasons, which could be useful to reduce the incidence of non tumoural nephrectomy in the pediatric population. There is need to emphasize the importance of early diagnosis of renal lesion in pediatric age group to prevent nephrectomy
ABSTRACT
A clinico-pathological study was carried out on 8 patients with microscopic polyar-teritis nodosa (MPAN). It was found that the renal lesions were very common and severe in this group of patients apart from the typical presentation of MPAN, including fever, myalgias, arteritis and the involvement of hematologic, gastrointestinal and cardiovascular systems. Laboratory pictures were characterized by leucocytosis, anemia and increased serum creatinine. The plasma anti-neutrophil cytoplasmic antibodies were present and thought to be of particular importance. On light microscopy, focal, segmental necrotising glomerulonephritis was discovered which was often associated with extensive crescence formation and vasculitis. We recommend renal biopsy as a valuable tool of investigation in the diagnosis of MPAN.