Clinical study on delayed regiment of CsA in cadaveric renal transplantation / 中华肾脏病杂志

Objective To study the effect of delayed cyclosporine(CsA) therapy combined with prophylactic use of antilympho-cyte globulin (ALG) (sequential quadruple immunosuppressive protocol) on early graft function in renal transplantation. Methods The experimental group included 90 renal recipients who were treated with posttransplant quadruple sequential therapy. Their short-term outcomes were compared with those of 215 recipients who were given CsA immediately after transplantation(control group). Results Not only was the recovery of renal allograft function faster in the experimental group ( P 0. 05). Conclusion Delayed CsA therapy in conjunction with prophylactic use of ALG is a desirable protocol for treating posltransplant renal recipients.