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ABSTRACT BACKGROUND: Epidemiological studies involving large samples usually face financial and operational challenges. OBJECTIVES: To describe the planning and execution of ADHERE Brazil, an epidemiological study on 1,105 kidney transplant patients, and report on how the study was structured, difficulties faced and solutions found. DESIGN AND SETTING: Cross-sectional multicenter study in 20 Brazilian kidney transplantation centers. METHODS: Actions developed in each phase of implementation were described, with emphasis on innovations used within the logistics of this study, aimed at estimating the prevalence of nonadherence to treatment. RESULTS: Coordination of activities was divided into four areas: general, regulatory, data collection and statistics. Weekly meetings were held for action planning. The general coordination team was in charge of project elaboration, choice of participating centers, definition of publication policy and monitoring other coordination teams. The regulatory team provided support to centers for submitting the project to ethics committees. The data collection team prepared a manual on the electronic collection system, scheduled web meetings and was available to respond to queries. It also monitored the data quality and reported any inadequacies found. Communication with the centers was through monthly reports via e-mail and distribution of exclusive material. The statistical team acted in all phases of the study, especially in creating the data analysis plan and data bank, generation of randomization lists and data extraction. CONCLUSIONS: Through these logistics, we collected high-quality data and built a local research infrastructure for further studies. We present supporting alternatives for conducting similar studies. CLINICAL TRIAL ANNOTATION: http://clinicaltrials.gov/ on October 10, 2013; NCT02066935.
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Humans , Kidney Transplantation , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , CommunicationABSTRACT
Objetivo: identificar el nivel de conocimiento de los empleados acerca de las políticas de investigación en las instituciones de salud de mediana y alta complejidad en el Valle de Aburrá, Colombia. Metodología: investigación de corte transversal, con aplicación de encuestas a 224 empleados en las instituciones prestadoras de servicios salud de alta (52) y mediana complejidad (322), públicas y privadas en el 2011. Resultados: en referencia al conocimiento de la existencia de políticas de investigación, se encontró que este es mayor en los empleados de las instituciones de alta complejidad (p=0,000). Más del 70% de los empleados encuestados manifestaron su interés en trabajar en proyectos de investigación. Conclusión: las instituciones de salud de alta complejidad y públicas tuvieron más desarrollos en investigación y se percibió gran interés por la investigación en los empleados del sector salud, con independencia del nivel de complejidad, del tipo de institución y del nivel de formación.
Objective: identifying the knowledge level of the employees regarding the research policies of mid and high complexity healthcare facilities in the Aburra Valley, Colombia. Methodology: cross-section research, with surveys for 224 employees of the healthcare providing institutions of high (52) and mid (322) complexity, both public and private, in 2011. Results: regarding the knowledge about the existence of research policies, we found that it is higher in the employees of high complexity institutions (p = 0.000). Over 70% of the employees surveyed showed their interest in working on research projects. Conclusion: public high complexity healthcare facilities showed more developments on research and we found great interest of the employees of the health sector on research, regardless of the complexity level, the type of facility, and education level.
Objetivo: identificar o nivel de conhecimento dos empregados sobre as políticas de pesquisa nas instituicoes de saúde de mediana e alta complexidade no Valle de Aburrá, Colombia. Metodologia: pesquisa de corte transversal, com aplicação de inquéritos a 224 empregados de instituicoes prestadoras de servicos de saúde de alta (52) e mediana complexidade (322), públicas e privadas no ano 2011. Resultados: no que diz respeito do conhecimento sobre a existencia de políticas de pesquisa, encontrou-se que é maior em empregados de instituicoes de alta complexidade (p = 0,000). Mais de 70 % dos empregados indagados manifestaram interesse por trabalhar em projetos de pesquisa. Conclusão: as instituicoes de saúde de alta complexidade públicas tiveram maior desenvolvimento de pesquisa e percebeu-se grande interesse dos empregados do sector saúde pela pesquisa, com independencia do nível de complexidade, do tipo de instituicao e do nível de formação.
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Translational medicine is a more effective and efficient way to improve the investment return on bioscience and provide equitable access to high—quality healthcare.Recognizing the need for a new impetus to spur clinical and translational research,the National Institutes of Health established the Clinical and Translational Science Awards Program.
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The authors discussed about how to integrate the advantages of different medical research resources to construct Shanghai Academy of Medical Sciences,which will provide substantial support for medical innovation in Shanghai.Principles were proposed concerning the administrative system and management mechanism to enhance the performance.The Academy is expected to improve medical research and clinical performance,especially to help resolve some major diseases and incurable diseases.Ultimately,the Academy will develop into an advanced research center linking laboratory research and clinical medicine.
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To improve the efficiency of medical research resource distribution in Beijing,based on the analysis of the existing problems we discussed the new model of resource integration.The model includes establishing all information-sharing platform and two operation modes of research project.By using this model it would be assured to achieve the best allocation efficiency and maximizing profits for Beijing medical research resources.