ABSTRACT
This study aimed to provide data support for resource utilization of the stems and leaves of Astragalus membranaceus var. mongholicus(SLAM) by analyzing and evaluating the chemical constituents. The crude protein, crude fiber, and soluble saccharide of SLAM were analyzed by Kjeldahl method, filtration method, and UV-Vis spectrophotometry, respectively. The nucleosides, amino acids, flavonoids, and saponins of SLAM were analyzed by ultraperformance liquid chromatography-triple quadrupole mass spectrometry(UPLC-TQ-MS). Combined with principal component analysis(PCA), the quality difference of resource components of SLAM was comprehensively evaluated. The results showed that the average content of crude protein, crude fiber, total polysaccharide, and redu-cing sugar in SLAM was 5.11%, 30.33%, 11.03 mg·g~(-1), and 31.90 mg·g~(-1), respectively. Six nucleosides, 15 amino acids, 22 flavonoids, and one saponin were detected, with an average content of 1.49 mg·g~(-1), 6.00 mg·g~(-1), 1.86 mg·g~(-1), and 35.67 μg·g~(-1), respectively. The content of various types of chemical components in SLAM differed greatly in different harvesting periods and growing years. The results of PCA showed that the quality of SLAM produced in Ningxia was superior. The results can provide references for the utilization of SLAM.
Subject(s)
Astragalus propinquus/chemistry , Gas Chromatography-Mass Spectrometry , Flavonoids/analysis , Plant Leaves/chemistry , Amino Acids , Saponins/analysisABSTRACT
Coptidis Rhizoma is one of the staple traditional Chinese medicinal materails in China with long officinal history, and its alkaloids provide the most important sources of precursor compounds in innovative drug research, which has been the focus of industry attention. This paper emphasized the industry development and summarized the alkaloid resource chemical constituents in Coptidis Rhizoma, and the progress of resource chemical research on Coptidis Rhizoma based on quality evaluation, structure modification and industrial application of the alkaloids was analyzed. The attention to the high value development of resource compounds and the use of “non-traditional medicinal tissues” for the limited resource Coptidis Rhizoma were proposed. The utilization ways and strategies provide important reference for the comprehensive development and resource recycling of Coptidis Rhizoma.
ABSTRACT
Rhei Radix et Rhizoma is one of the most important Chinese medicinal materials in China, which is also a typical representative herb with multiple effects, multiple species, and multiple genuine production areas. In this paper, the chemical constituents of Rhei Radix et Rhizoma were systematically summed up, and the progress of the chemical research on Rhei Radix et Rhizoma based on different varieties, different habitats, different harvest periods, and different tissues were analyzed. The attention to regional change and harvest time, the application of “efficacy bias” for different varieties, the utilization of “non medicinal tissues”, and the high value development of resource components were proposed. The utilization ways and strategies provide important reference for the comprehensive development and utilization of rhubarb resources.
ABSTRACT
The harvest time of traditional Chinese medicinal materials (TCMM) is a very essential part for production of TCMM, and affects their quality and yield. The research on the best harvest time of TCMM has been a key problem taken into account more and more with practicing GAP of TCMM. Based on thoughts and methods of resource chemistry, this paper established an evaluated mode to objectively determine the best harvest time of Angelica sinensis through system investigating from different producing areas and harvest times, and characterize the phenology and multi-index components comprehensive criteria. The author firstly proposed the suitable methods of the best harvest time of TCMM, which was a basis of theory and methods of resource chemistry of TCMM, and including the time-space relationships and laws of substances dynamic accumulation. These data could provide the guidance for standardized production and guaranteed quality and yield of TCMM.