ABSTRACT
Background: The purpose of the present study was to determine whether there was a relationship between periodontal diseases and ABO blood groups. Methods: This epidemiological study was carried out on 300 subjects who were randomly selected from individuals referred to the periodontics of Ahmedabad Dental College & Hospital for periodontal treatment or for other reasons regarding dental health. The study based on periodontal condition, blood group. The effects of blood subgroups on periodontal health, gingivitis and Periodontitis were investigated separately. Results: The findings of our study revealed that subject’s blood group “O” and “B”, Rh positive had a greater propensity for periodontitis followed by blood group A and least prevalent is blood group AB. Conclusions: ABO blood subgroups and Rh factor may constitute a risk factor on the development of periodontal disease.
ABSTRACT
La determinación del grupo sanguíneo y el factor Rh son importantes en el campo de la biología, genética y en la práctica médica por su valor clínico en las transfusiones sanguíneas. Por ello, en la presente investigación se tipificó el grupo sanguíneo de la población de Totora y se analizó su prevalencia tanto en hombres como mujeres. Se realizó un estudio descriptivo, de corte transversal; en una población total de 12 961, del cual se obtuvo una muestra de 175 personas, comprendidas entre las edades de 18 a 84 años que dieron su consentimiento; se excluyó al resto de la población que no quiso participar y que no tuvo acceso al estudio. Para la determinación del grupo sanguíneo y factor Rh se utilizaron los reactivos de la marca DIALAB ® importados de Australia, siguiendo el protocolo establecido. El control de calidad del Kit se realizó con sangre ya tipificada, proporcionada por el Banco de Sangre de Cochabamba. Los resultados mostraron un predominio de grupo sanguíneo O con 85 %, seguido del tipo A con 9%, tipo B 6%, no habiendo resultados para el grupo sanguíneo AB; en cuanto al factor Rh las personas con el factor Rh positivo representan el 99% y el factor Rh negativo 1%. El grupo sanguíneo O y el factor Rh positivo es el predominante en ambos sexos.
The blood grouping and Rh factor are important in the field of biology, genetic and medical practice because of its clinical value in blood transfusions.Thus in the present investigation it was typified the blood group of Totora's population and analyzed its prevalence in both men and women. By performing a descriptive, cross-sectional study, in a total population of 12 961, in which it was obtained a sample of 175 people between the ages of 18-84 years old who assented to the study; the rest of the population that declined to participate and had no access to education were excluded. To determine the blood group and Rh factor it was used DIALAB ® brand reagents imported from Australia, following the established protocol.The quality control was performed with blood Kit typified, provided by the Blood Bank of Cochabamba. The results showed a predominance of blood group O with 85%, followed by 9% of type A, type B 6%, not having results for blood group AB, Rh factor regarding people with Rh-positive, representing 99 %, and Rh-negative it was 1%. Blood group O and positive Rh factor is dominant in both sexes.
ABSTRACT
Background & objectives: There is paucity of information on the association between Plasmodium falciparum malaria and some human genetic markers in the Niger Delta region of Nigeria. Hence, a study was undertaken in children to assess the current level of subclinical malaria due to P. falciparum. Methods: Blood groups ABO and Rhesus factor, haemoglobin electrophoretic pattern, G-6-PD deficiency status and malaria were determined among 240 apparently healthy children in a crosssectional descriptive study using standard procedures. Results: The prevalence of P. falciparum malaria in this region was high (27.5%). Blood group O (51.3%) dominated the study population, followed by B (23.8%), A (21.3%), and AB (3.8%). Rhesus D positive accounted for 91.3% while Rh D negative was 8.7%. Sickle-cell trait (HbAS) prevalence was 12.5% while HbAA accounted for 87.5%. In all, 5.42% of the children were G-6- PD deficient while 94.58% had normal G-6-PD status. Chi-square analysis revealed that only blood group O and Rh D negative had a significant association with P. falciparum malaria (2= 4.3636, p <0.05 and 2 = 5.760, p <0.02 respectively). No significant association was found to exist between P. falciparum malaria and other genetic markers. Conclusion: This study has provided the current prevalence rates of some genetic markers in a malaria endemic region of Niger Delta, Nigeria. Of all the genetic markers tested, only Blood group O and Rh D negative had significant and positive associations with P. falciparum infection.