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Rev. chil. obstet. ginecol ; 76(3): 188-206, 2011. ilus
Article in Spanish | LILACS | ID: lil-597585

ABSTRACT

En solo 50 años la enfermedad hemolítica perinatal por isoinmunización anti D pasó de ser una enfermedad sin etiología conocida, incurable y no prevenible, a la situación actual en que por las técnicas de prevención, diagnóstico oportuno y tratamiento especializado tiene baja incidencia y altas expectativas de sobrevida, incluso en los casos más severos. Se describe la historia, las técnicas de prevención, diagnóstico, manejo y tratamiento de la enfermedad.


In just 50 years the perinatal hemolytic disease due to RhD isoimmunization went from being a disease without known etiology, untreatable and not preventable to the current situation in which the prevention techniques, opportune diagnosis and specialized treatment has low its incidence and has an expected high survival even in the more severe cases. This article describes the history, prevention techniques, diagnosis, management and treatment of the disease.


Subject(s)
Humans , Female , Pregnancy , Erythroblastosis, Fetal/classification , Erythroblastosis, Fetal/diagnosis , Erythroblastosis, Fetal/therapy , Rh Isoimmunization/diagnosis , Rh-Hr Blood-Group System , Middle Cerebral Artery , Blood Flow Velocity , Blood Transfusion, Intrauterine , Bilirubin/analysis , Coombs Test , Cordocentesis , Fetal Blood , Hematocrit , Fetal Hemoglobin/analysis , Rh Isoimmunization/prevention & control , Amniotic Fluid/chemistry , Reference Values , Risk Factors , Severity of Illness Index , Spectrophotometry
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