ABSTRACT
@#Non-infectious corneal ulceration after uneventful phacoemulsification cataract surgery is a rare complication after cataract surgery. It may be associated with autoimmune conditions and neurotrophic corneal epitheliopathy in patients. Rheumatoid disease, arthritis, Sjogren's syndrome, Crohn's disease, tuberculosis and using non-steroidal anti-inflammatory drugs are all high-risk factors for corneal ulceration after cataract surgery. This article reviews the cases report and clinical manifestations, mechanism of occurrence, prevention and treatment of corneal non-infectious ulceration after cataract surgery.
ABSTRACT
Se presenta un caso, portadora de artritis reumatoide de varios años de evolución, que tras abandonar el tratamiento presentó una exacerbación de la actividad de la enfermedad, acompañada de un síndrome general y lesiones dérmicas y neurológicas producidas por una vasculitis leucocitoclastica, fue necesario actualizar el tratamiento con metotrexate y bolos de metilprednisolona obteniendo una respuesta favorable demostrada al desaparecer la actividad de la enfermedad y cicatrización de las lesiones ulcerosas.
present a case, with rheumatoid arthritis of several years of evolution, that after leaving the treatment presented an exacerbation of the activity of the disease, accompanied by a general syndrome and dermal and neurological lesions caused by a leukocytoclastic vasculitis, it was necessary to update the treatment with methotrexate and boluses of methylprednisolone obtaining a favorable response demonstrated when the activity of the disease disappeared and cicatrization of the ulcerous lesions.
ABSTRACT
PURPOSE: To evaluate the ocular manifestations of patients with rheumatic disease and dry eye symptom. METHODS: We analized the results of ocular examinations and complications of 78 rheumatoid disease patients who were refered for dry eye symptom from the general medicine from 1998, May to 1999, May. RESULTS: Ocular complications were seen in 47 patients (60.3%). Keratoconjunctivitis sicca was the most common ocular finding (48.7%). Other lesions were episcleritis, scleritis, peripheral corneal erosion, marginal keratitis, stromal corneal opacity, and so on. Thirty six patients (46.2%) showed sero-positivity for RA, ANA or CRP. The result was 6.87+/-4.44 mm (mean+/-standard deviation) in Schirmer test,6.64+/-2.27 sec in Tear Film Break Up Time (TBUT). Among sero-positive patients, Schirmer test was 5.46+/-4.05 mm and TBUT was 5.64+/-2.38 sec, while among sero-negatives the result was 8.21+/-4.33 mm, 7.40+/-1.89 sec respectively. It was statistically significant (P< 0.05). Schirmer test was 4.60+/-3.55 mm in RA positive, 2.50+/-1.60 mm in RA and ANA positive, 7.35+/-4.92 mm in CRP positive. TBUT was 5.57+/-2.39 sec, 4.00+/-1.31 sec, 5.69+/-2.04 sec in each group. CONCLUSIONS: Ocular complications were increased in rheumatoid patients, especially with sero-positive for RA, ANA or CRP. The results of Schirmer test and TBUT were most decreased in patients with RA and ANA positivity.