Rhodotorula mucilaginosa Keratitis: A rare fungus from Eastern India.

Rhodotorula muci laginosa r a r e l y c a u s e k e r a t i t i s i n immunocompromised individuals. A 30 year old male with history of minor trauma presented with cotton wool like stromal infiltration and hypopyon in left eye. Microbiological examination of corneal scraping showed fungal hyphae and yeast cells in direct smear. Molecular identification of the organism was performed which showed 100% homology with Rhodotorula mucilaginosa. Management of these cases is difficult often necessitating surgical procedures. However further reports are necessary to understand the disease and establish a treatment protocol.

Antifungal activity of four honeys of different types from Algeria against pathogenic yeast:Candida albicans and Rhodotorula sp

Objective: To evaluate the antifungal activity of four honeys of different types from Algeria against pathogenic yeast i.e. Candida albicans (C. albicans) and Rhodotorula sp. Methods:Four Algeria honeys of different botanical origin were analyzed to test antifungal effect against C. albicans, and Rhodotorula sp. Different concentrations (undiluted, 10%, 30%, 50%and 70%w/v) of honey were studied in vitro for their antifugal activity using C. albicans and Rhodotorula sp. as fungal strains. Results:The range of the diameter of zone of inhibition of various concentrations of tested honeys was (7-23 mm) for Rhodotorula sp., while C. albicans showed clearly resistance towards all concentrations used. The MICs of tested honey concentrations against C. albicans and Rhodotorula sp. were (70.09-93.48)%and (4.90-99.70)%v/v, respectively. Conclusions:This study demonstrates that, in vitro, these natural products have clearly an antifungal activity against Rhodotorula sp. and C. albicans.

Aislamiento de Rhodotorula sp. en un paciente críticamente enfermo Descripción de un caso y revisión de la literatura / Rhodotorula sp. Isolate in a critically ill patient. Case report and review

Los reportes de infecciones micóticas diseminadasdebido a los miembros del orden criptococalesse han limitado al Cryptococcus y Candida. La Rhodotorula es una levadura encontrada en la piel, esputo y excretas de los seres humanos. Morfológica y bioquímicamente se caracteriza por producir un llamativo pigmento rojizo, no asimilar el inositol y tener ocasionalmente rudimentarios pseudomicelios (1-4). Las infecciones causadas por este agente soninfrecuentes en la práctica clínica. Algunos centrosespecializados en cáncer reportan series decasos en las décadas anteriores a 1980 (2).

Study on antarctic yeast Rhodotorula sp.NJ-298 producing astaxanthin / 中国海洋药物

A yeast strain Rhodotorula sp.NJ-298,which was isolated from antarctic sea-ice,could produce carotenoids pigment,and the total production was 1986?g?g~(-1).UV-visible spectrum and LC/MS analysis indicated astaxanthin was the major component of the carotenoids,and HPLC analysis showed its content accounted for 81.9 % of total carotenoids productoin.Maximum astaxanthin production 6506 ?g?L~(-1) was obtained when the yeast was grown at steady-state phase.Optimum temperature for the strain grow was at 8℃,and sodium acetate and peptone were the best carbon and nitrogen sources for the astaxanthin production.Moreover,the pigment had strong activity of scavenging free radicals,and the IC_(50) was 0.40 ?g?mL~(-1) by DPPH assay.