Relationship of balance in static single-leg stance to muscle strength and position sense of ankle in individuals with functional ankle instability / 中国康复理论与实践

ObjectiveTo analyze the relationship of the static single-leg stance balance with ankle muscles strength and position sense in individuals with functional ankle instability (FAI). MethodsFrom March to May, 2023, 44 FAI individuals were recruited in Hebei Normal University, and the maximum isokinetic muscle strength (60°/s and 180°/s) and position sense as ankle flexion, extension, inversion and eversion were measured using isokinetic dynamometer; while the center of pressure (COP) sway distance and envelope area were measured as static single-leg stance with eyes open or closed using three-dimensional force plate. ResultsThe maximum isokinetic torque as ankle eversion at 180°/s correlated with the COP anterior-posterior sway distance with eyes closed (r = -0.378, P < 0.05). ConclusionExplosive ankle eversion strength is related with the balance in static single-leg stance, which may help to evaluate and intervent the ankle function of FAI individuals.

Analysis on Collective Moral Injury / 中国医学伦理学

The previous moral injury theory implied the premise of taking individual as the research object, while there were few studies on collective moral injury. Collective moral injury is defined as a series of consequences of violating widely accepted moral beliefs rather than simply adding up symptoms of injured individuals within a group. From the America "Floyd Case", this paper analyzed the functional elements and generating mechanism of collective moral injury, that was, the diversification of trauma sources events could appear alone or interweave, collective moral resilience showed the characteristics of social integrity and time accumulation, the interaction between collective trauma sources and collective moral resilience determined whether collective moral injury occurs. As the We-Media become popular, collective feature of moral injury is more evident, which presents two new features that the Internet platform becomes a hub for trauma events and the information Internet recorded consolidates collective moral resilience. To deal with collective moral injury, it was needed to respond to social concerns and guidance moral public opinion, respect the original endogenous order and inherit the traditional culture, satisfy reasonable moral needs and enlighten moral sense of people as well.

Analysis of impaired vibrotactile sense in patients with schizophrenia and depressive disorders / 四川精神卫生

BackgroundPatients with schizophrenia and depressive disorders exhibit abnormalities in perceptual processing. Previous perceptual studies are mainly based on asking participants to fill in a questionnaire， and little research has been undertaken on objective behavior in patients with schizophrenia and depressive disorders. ObjectiveTo explore the behavioral changes in vibrotactile sense among patients with schizophrenia and depressive disorders， so as to enrich relevant findings in objective behavioral research. MethodsFrom March 2021 to September 2023， 33 patients with schizophrenia and 31 patients with depressive disorders in the outpatient and inpatient departments of Beijing Huilongguan Hospital and met the Diagnostic and Statistical Manual of Mental Disorders， fifth edition （DSM-5） diagnostic criteria were enrolled. And another 34 healthy controls were concurrently recruited at Beihang University and Beijing Huilongguan Hospital. Patients with schizophrenia were assessed using Positive and Negative Symptom Scale （PANSS）， and patients with depressive disorders were assessed using Hamilton Depression Scale-17 item （HAMD-17）. The vibrotactile sensitivity of the left hand in all participants was tested in a delay match-to-sample procedure， and the correct rate of vibrotactile delayed discrimination task was compared among the three groups. ResultsCompared with healthy controls， a reduction was found in the correct rates at index finger， middle finger and ring finger in patients with schizophrenia （P<0.01）， the average correct rate at five fingers in patients with schizophrenia （P=0.001）， and the correct rate at thumb in patients with depressive disorders （P=0.026）. No statistical difference was reported in correct rate of vibrotactile delayed discrimination task between patients with depression disorders and schizophrenia （P>0.05）. The average correct rate of vibrotactile sense in schizophrenia group was not significantly correlated with the duration of disease， age of onset， chlorpromazine equivalent doses and PANSS score （r=0.058、0.045、0.114、-0.194， P>0.05）. The average correct rate in depressive group was negatively correlated with age of onset （r=-0.415， P=0.020）， but not significantly correlated with the duration of disease and HAMD-17 score （r=-0.044， 0.142， P>0.05）. ConclusionPatients with schizophrenia and depressive disorders have impaired vibrotactile sense. The vibrotactile sense is impaired in index， middle and ring fingers among patients with schizophrenia， and in thumbs of patients with depressive disorders. Moreover， the impairment in patients with depressive disorders may be related to the age of onset. ［Funded by 2023 Hebei Provincial Graduate Innovation Funding Project （number， CXZZSS2023140）］

Síndrome de Burnout e o senso de coerência em profissionais de enfermagem / Burnout syndrome and coherence sense in nursing professionals

Este estudo analisou a síndrome de Burnout e o senso de coerência em profissionais de enfermagem durante a pandemia de COVID-19. Para tanto, 61 profissionais da região Centro-Oeste do Brasil responderam aos instrumentos Maslach Burnout Inventory (MBI) e Senso de Coerência (SOC), em questionário do Google Forms. Os resultados indicaram que o domínio com maior pontuação média no MBI foi a "Realização pessoal" (M=3,95; DP=0,53), seguida pela "Exaustão emocional" (M=2,82; DP=0,83). Houve associação significante entre domínios do MBI e as dimensões do SOC-13, com pontuações mais altas em "Compreensão" e "Manejo" do SOC, associadas a menor "Exaustão emocional" (r_S de -0,447 e -0,572) e "Despersonalização" (r_S de -0,339 e -0,383). Foi observada relação significante entre o apoio psicológico no trabalho e a redução do nível de exaustão (valor p ≤ 0,001). Esses achados fornecem contribuições relevantes para o desenvolvimento de ações direcionadas aos profissionais da enfermagem, destacando a importância do apoio psicológico e do fortalecimento do senso de coerência.

This study analyzed Burnout and sense of coherence in nursing professionals during the COVID-19 pandemic. To do so, 61 professionals of the Center-West region of Brazil answered the Maslach Burnout Inventory (MBI) and Sense of Coherence (SOC) instruments through a Google Forms questionnaire. The results suggested that the domain with the highest mean score in the MBI was "Personal accomplishment" (M=3.95; SD=0,53), followed by "Emotional exhaustion" (M=2.82; SD=0,83). There was a significant association between the MBI domains and the SOC-13 dimensions, with higher scores in "Comprehensibility" and "Manageability" of SOC, associated to lower "Emotional exhaustion" (r_S of -0.447 and -0.572) e "Depersonalization" (r_S of -0.339 and -0.383). A significant relationship was found between the psychological support at work and a decrease in the exhaustion level (p-value ≤ 0.001). These findings provide relevant contributions to devise actions focused on nursing professionals, highlighting the importance of psychological support and the strengthening of the sense of coherence.

Profile of Ankle Isokinetic Strength and Proprioception in Elite Female Handball Players / Perfil de Fuerza Isokinética del Tobillo y Propiocepción en Jugadoras de Balonmano de Élite

SUMMARY: The evaluation of the invertor and evertor muscle strength and proprioception are important in terms of determining the risk of injury in handball players. The aim of this study was to determine the isokinetic strength and proprioception profile of the ankle invertor and evertor muscles of elite female handball players. Fifteen elite female handball players were included. Ankle invertor and evertor muscle strength and proprioception were evaluated using the isokinetic system. The isokinetic strength test was performed in concentric mode at 30°/s (5 repetitions) and 120°/s (10 repetitions). Proprioception sense was evaluated as active joint position sense. There was no statistically significant difference between the dominant and nondominant sides in terms of invertor and evertor muscle strength, evertor/invertor (Ever/Inver) ratio, and active joint position sense at both angular speeds (p>0.05). The Ever/Inver ratio on both sides was lower than normal values. It was concluded that the female handball players showed bilateral symmetry in the invertor and evertor muscles. However, the fact that the Ever/Inver strength ratio was lower than normal values on both sides suggested that caution should be exercised in terms of risks such as ankle sprain or chronic ankle instability. Pre-season evaluations should be made and it would be beneficial to add strengthening exercises to related muscle groups in training programs to normalize the unilateral ratios in these athletes.

La evaluación de la fuerza muscular inversora y eversora y la propiocepción son importantes para determinar el riesgo de lesión en los jugadores de balonmano. El objetivo de este estudio fue determinar la fuerza isocinética y el perfil de propiocepción de los músculos inversores y eversores del tobillo de jugadoras de balonmano de élite. Se incluyeron 15 jugadoras de élite de balonmano. La fuerza muscular inversora y eversora del tobillo y la propiocepción se evaluaron mediante el sistema isocinético. El test de fuerza isocinética se realizó en modo concéntrico a 30º/s (5 repeticiones) y 120º/s (10 repeticiones). El sentido de propiocepción se evaluó como sentido activo de posición articular. No hubo diferencias estadísticamente significativas entre los lados dominante y no dominante en términos de fuerza muscular inversora y eversora, relación eversor/inversor (Ever/ Inver) y sentido activo de la posición de la articulación en ambas velocidades angulares (p>0.05). La relación Ever/Inver en ambos lados fue inferior a los valores normales. Se concluyó que las jugadoras de balonmano presentaron simetría bilateral en los músculos inversores y eversores. Sin embargo, el hecho de que la relación de fuerza Ever/Inver fuera inferior a los valores normales en ambos lados sugirió que se debe tener precaución en términos de riesgos como el esguince de tobillo o la inestabilidad crónica de tobillo. Se deben realizar evaluaciones de pretemporada y sería beneficioso agregar ejercicios de fortalecimiento a los grupos musculares relacionados en los programas de entrenamiento para normalizar las proporciones unilaterales en estas atletas.

Comprensión del valor de posición: equivalencia numérica y composición aditiva como facilitadores en la escritura de numerales / Understanding Place Value: Numerical Equivalence and Additive Composition as Predictors for Writing Numerals / Compreendendo o valor posicional: equivalência numérica e composição aditiva como facilitadores na escrita de numerais

El valor de posición es una propiedad básica de los formatos de representación del Sistema de Numera- ción en Base Diez (SNBD), y su comprensión facilita el desempeño matemático de los estudiantes en diferentes grados escolares. Algunas investigaciones sugieren que nociones como la composición aditiva y la equivalencia numérica participan en la emergencia de la comprensión de este principio, sin embargo, pocos estudios han intentado analizar la relación entre estas nociones o se han interesado en indagar ­desde una perspectiva de la transcodificación numérica­, cómo estas afectan la producción de numerales arábigos durante los procesos iniciales del aprendizaje escolar. En tal sentido, esta investigación propone indagar si algunas de las invariantes del SNBD ­composición aditiva y equivalencia numérica­ facilitan la comprensión del valor de posición y la escritura numérica en estudiantes de primer grado de primaria. Participaron 96 estudiantes adscritos a escuelas públicas de Cali, Colombia, en un estudio cuasi-experimental pre-posprueba con grupo control, que involucra la aplicación de un proceso de intervención diferente para cada grupo experimental: composición aditiva y (b) equivalencia numérica. Los resultados plantean que los dos tratamientos apli- cados facilitan la comprensión del valor de posición y generan efectos diferentes en la comprensión y producción de numerales arábigos. Además, los análisis develan cambios significativos entre aplicaciones para los grupos experimentales, pero no para el grupo con- trol, lo cual sugiere que la composición aditiva y la equivalencia numérica son predictores en la escritura correcta de numerales.

The place value is a fundamental property of the base-10 system representation formats, and its under- standing facilitates the mathematical performance of children in different school grades. Some research sug- gests that notions such as additive composition and nu- merical equivalence participate in the emergence of the understanding of this principle. However, few studies have attempted to analyze the relationship between these notions or have been interested in investigating ­from a transcoding perspective numerical­ how these affect the production of Arabic numerals during the initial processes of school learning. This research explores how some invariants of the base-10 system: Additive Composition and Numerical Equivalence, facilitate the place value mastery and the numerical writing of children. First-grade students (n= 96) linked to public schools in the city of Cali, Colombia, in a quasi-experimental experimental study with a control group, which involves the application of different in- tervention processes to each experimental group: (a) numerical equivalence and (b) additive composition. The results suggest that both treatments facilitate the place value understanding and generate differ- ent effects on comprehending and producing Arabic numerals. In addition, analyses reveal significant changes between applications for the experimental groups but not for the group control, which specif- ically evidences both the additive composition and the numerical equivalence are predictors in correct number writing.

O valor posicional é uma propriedade básica dos forma- tos de representação do Sistema de Numeração Base Dez (SNBD), e sua compreensão facilita o desempenho mate- mático de alunos de diferentes séries escolares. Algumas pesquisas sugerem que noções como composição aditiva e equivalência numérica participam do surgimento da compreensão desse princípio, porém, poucos estudos têm tentado analisar a relação entre essas noções ou se interessado em investigar ­a partir de uma perspectiva de transcodificação numérica­ como essas afetam a produção de algarismos arábicos durante os processos iniciais de aprendizagem escolar. Esta investigação se propõe a investigar se alguns dos invariantes do SNBD; a composição aditiva e a equivalência numérica facilitam a compreensão do valor posicional e da escrita numérica em alunos da primeira série. Participaram do experi- mento 96 alunos da primeira série de escolas públicas de Cali, Colômbia; num estudo quase experimental pré/pós-teste com um grupo controle, que envolve a aplicação de um processo de intervenção diferen- te a cada grupo experimental; (a) composição aditiva e (b) equivalência numérica. Os resultados sugerem que os dois tratamentos aplicados facilitam a compreensão do valor posicional e geram efeitos diferentes na com- preensão e produção dos algarismos arábicos. Além disso, as análises revelam mudanças significativas entre as aplicações para os grupos experimentais, mas não para o grupo controle, o que sugere que a composi- ção aditiva e a equivalência numérica são preditores na escrita correta dos numerais.

Sentidos y significados atribuidos al autoempleo por cuatro profesionistas de la psicología en el contexto mexicano

La flexibilización y precarización estructural del trabajo han llevado, entre otros trabajadores, a un grupo de profesionistas de la psicología a identificar en el autoempleo una forma viable para desempeñarse en la actualidad. Esta experiencia ha representado para ellos una actividad performática que los reta a reinventarse continuamente para adaptarse a los cambios del mercado laboral y que trasforma los sentidos y significados que atribuyen al autoempleo. Con el objetivo de conocer y comprender esos sentidos y significados atribuidos al autoempleo, por medio de un estudio cualitativo de las narrativas y asociaciones de tres psicólogas y un psicólogo autoempleados en México se realizó este estudio. Los resultados develan las experiencias de autoempleo como articulación entre nuevas libertades y dependencias, que significan el trabajo para las y los participantes y desmitifican algunas retóricas del autoempleo. Concluimos que es urgente que las políticas laborales y educativas correspondan a estas realidades actuales del ejercicio libre de las profesiones, no sólo de la psicología.

The flexibilization and structural precariousness of work have led, among other workers, a group of psychology professionals to identify self-employment as a viable way of working in today's world. This experience has represented for them a performative activity, challenging them to reinvent continually themselves in order to adapt to changes in the labor market and transforming the sense and meanings they attribute to self-employment. With the objective to know and understand the sense and meaning attributed to work, the narratives and associations of four self-employed psychologists in Mexico were analyzed through a qualitative study. The results disclose the experiences of self-employment as an articulation between new freedoms and dependencies, which signify work for the participants and demystify some self-employment rhetoric. There is an urgent need for labor and educational policies to adjust to the actual realities of free professionals' practice, not only in the field of psychology.

A flexibilidade e a precariedade estrutural do trabalho levaram, entre outros trabalhadores, um grupo de profissionais da psicologia a identificar no trabalho autônomo uma forma viável de atuar na atualidade. Esta experiência tem representado para eles uma atividade de desempenho que os desafia a reinventar-se continuamente para se adaptar às mudanças do mercado de trabalho e que transforma os sentidos e significados que atribuem ao trabalho por conta própria. Este estudo foi realizado com o objetivo de conhecer e compreender esses sentidos e significados atribuídos ao trabalho autônomo, através de um estudo qualitativo das narrativas e associações de três psicólogos e psicólogos autônomos no México. Os resultados revelam as vivências do trabalho autônomo como articulação entre novas liberdades e dependências, que significam trabalho para os participantes e desmistificam algumas retóricas do trabalho autônomo. Concluímos que é urgente que as políticas laborais e educativas correspondam a estas realidades atuais do livre exercício das profissões, não só da psicologia.

Sensory remapping: a possible therapy option / Remapeamento sensorial: uma possível opção de terapia

The human sensory receptors are morphologically specialized to transduce specific stimuli into the brain. However, when an injury occurs, mainly in the spinal cord, which can be of traumatic or non-traumatic origin, it provokes various degrees of sensory deficits, autonomic, motor and sphincter dysfunction below the level of the injury. Based on this, a new therapeutic modality is being proposed by neuroscientist Miguel Nicolelis, which is based on the brain-machine interface, that is, using other pathways so that the information can reach the cerebral cortex and thus be consciously processed (AU).

Os receptores sensoriais humanos são morfologicamente especializados para realizar a transdução de estímulos específicos para o encéfalo. Entretanto, quando ocorre uma lesão, principalmente, na medula espinal, que pode ser de origem traumática e não traumática, provocam diversos graus de déficits sensoriais, disfunção autônoma, motora e esfincteriana, abaixo do nível da lesão. Com base nisso, uma nova modalidade terapêutica está sendo proposto pelo neurocientista Miguel Nicolelis, que tem como base a interface cérebro máquina, isto é, utilizar-se de outras vias para que as informações possam chegar no córtex cerebral e assim serem processadas conscientemente.Palavras-chave: Interfaces cérebro-computador, Neurociências, Órgãos dos sentidos (AU).

Escala de Significados del Sentido del Humor / Sense of Humor Meanings Scale

Resumen El Sentido del Humor (SH) es considerado un fenómeno universal, pero al mismo tiempo culturalmente específico pues cada grupo posee particularidades que modulan la forma en la éste se percibe y conceptualiza. Aunque el trabajo empírico en torno al fenómeno es amplio, éste se ha centrado en la creación de escalas que miden estilos particulares de humor o ciertos dominios humorísticos, dejando de lado el interés por explorar lo más fundamental, es decir, las percepciones y significados generales del humor. Dado lo anterior, el presente trabajo tuvo por objetivos: 1) explorar el significado atribuido al SH por hombres y mujeres, 2) desarrollar un instrumento válido y confiable para adultos mexicanos, 3) examinar la invarianza de la medición de dicho instrumento en función del sexo de los participantes e 4) identificar posibles diferencias entre hombres y mujeres al respecto de los factores de la medida validada. Los resultados mostraron la obtención de tres categorías que son congruentes con los factores obtenidos en la escala diseñada. En cuanto a sus características resultó una escala válida y confiable, que mostró equivalencia entre los sexos.

Abstract The Sense of Humor (SH) is considered a universal phenomenon, but at the same time culturally specific, since each group has particularities that modulate the way in which it is perceived and conceptualized. Although the empirical work around the phenomenon is extensive, it has focused on the creation of scales that measure styles of humor or certain humorous domains, leaving aside the interest in exploring what is most fundamental, that is, the general perceptions and meanings of humor. humor. Given the above, the present work had the objectives: 1) to explore the meaning attributed to SH by men and women, 2) to develop a valid and reliable instrument for Mexican adults, 3) to examine the invariance of the measurement of said instrument based on the gender and 4) identify possible differences between genders regarding the factors of the validated measure. The results showed the obtaining of three categories that are consistent with the factors obtained in the designed scale. Regarding its characteristics, it was a valid and reliable scale, which showed equivalence between genders.

Identification of taste critical quality attribute and formulation optimization of Xiaoer Qingrening Granules based on electronic tongue and human senses / 药学学报

This study primarily concentrated on scientific problems of poor taste caused by unclear critical quality attributes of oral preparations manufactured by Chinese materia medica, successfully established an identification method for taste critical quality attribute and a taste improvement method combining electronic tongue with human senses, and determined the optimal taste formula, to improve patients' oral medication compliance. The study received ethical approval from the Review Committee of the Beijing University of Chinese Medicine. The results showed that the proportion of bitterness of Xiaoer Qingrening Granule was 61.8%, and its bitterness grade was 3.70, it was determined that bitterness is the critical quality attribute that caused the poor taste of Xiaoer Qingrening Granule. Additionally, the optimal taste formula per milliliter of Xiaoer Qingrening sugar-free intermediate was determined with allowable daily intake, solubility, and sweetness as the limiting conditions, which was 40 mg hydroxypropyl β-cyclodextrin, 180 mg trehalose, and 1.5 mg acesulfame potassium. Compared with the Xiaoer Qingrening Granule, the sensory evaluation score of the optimal taste formula was increased by 37.5 points. In conclusion, this study achieved the taste improvement of Xiaoer Qingrening Granule and formed a set of taste improvement strategies including the identification of taste critical quality attribute, the selection of the type and dosage of corrigent, and the optimization of taste formula, which provided a thought reference for the taste improvement of other oral preparations and a new perspective for quality control of intelligent manufacturing of traditional Chinese medicines.

Recovery of proprioception after lateral ankle sprain / 中国康复理论与实践

ObjectiveTo observe the recovery of proprioception of the affected ankle over time after lateral ankle sprain accepting routine rehabilitation. MethodsFrom June, 2020 to June, 2022, 18 patients with lateral ankle sprain in Kunshan Rehabilitation Hospital underwent routine rehabilitation for twelve weeks. They were measured active and passive position sense of bilateral ankles using an isokinetic dynamometer before treatment, and four, eight and twelve weeks after treatment, respectively. ResultsThe active presentation difference of affected ankle reduced after treatment (F = 22.533, P < 0.001), but it was more than that of the healthy ankle at the same time (t > 4.419, P < 0.001). No significant improvement was found in passive presentation difference of affected ankle after treatment (F = 1.175, P > 0.05), and it was not significantly different from those of the healthy ankle at the same time (|t| < 0.646, P > 0.05). ConclusionProprioception of affected ankle has been impaired after lateral ankle sprain, and it can be recovered after rehabilitation, but cannot achieve the healthy level even after three months of training. Passive position sense as an index of proprioception needs more researches.

Resources for health maintenance in persons deprived of liberty with arterial hypertension: a salutogenic approach / Recursos para el mantenimiento de la salud en prisioneros con hipertensión arterial: un enfoque saludgénico / Recursos para manutenção da saúde em pessoas presas com hipertensão arterial: uma abordagem salutogênica

ABSTRACT Objective: to know the generalized resistance resources of people deprived of liberty with systemic arterial hypertension in a triple border region. Method: a qualitative study based on the theoretical framework of Salutogenesis, in which 38 people deprived of liberty in Foz do Iguaçu, Paraná, Brazil, participated from February to July 2022. Guiding questions were used in the interviews which were submitted to thematic content analysis. Results: 12 generalized resistance resources emerged in the reports of people deprived of liberty with systemic arterial hypertension: health team; access to medications; work; lifestyle habits: food, physical activity and restriction of access to drugs/cigarettes/alcoholic beverages; stress/anxiety control; reading and games; religiosity; family; self-care; cellmates; and employees. Conclusion: people deprived of liberty with systemic arterial hypertension have generalized resistance resources to manage their life and health, which are related to personal care, the social group and the environment. It is noteworthy that once they are identified, the generalized resistance resources can be used by health professionals to manage SAH, other chronic diseases and aid in health promotion.

RESUMEN Objetivo: conocer los recursos generalizados de resistencia de las personas privadas de libertad con hipertensión arterial sistémica en una región de la triple frontera. Método: investigación cualitativa basada en el referencial teórico de la Salutogénesis, en la que participaron 38 personas privadas de libertad de Foz do Iguazú, Paraná, Brasil, de febrero a julio de 2022. Se utilizaron preguntas orientadoras en las entrevistas, que fueron sometidas al análisis de contenido en la modalidad temática. Resultados: 12 recursos generalizados de resistencia surgieron en los relatos de detenidos con hipertensión arterial sistémica: equipo de salud; acceso a medicamentos; trabajar; hábitos de vida: alimentación, actividad física y restricción de acceso a drogas/cigarrillos/bebidas alcohólicas; control del estrés/ansiedad; lectura y juegos; religiosidad; familia; cuidados personales; compañeros de cubículo y empleados. Conclusión: las personas privadas de libertad con hipertensión arterial sistémica poseen recursos generalizados de resistencia para el manejo de su vida y salud, los cuales están relacionados con el cuidado personal, el grupo social y el medio ambiente. Se destaca que, una vez identificados, los recursos generalizados de resistencia pueden ser utilizados por los profesionales de la salud en el manejo de la HAS, otras enfermedades crónicas y promoción de la salud.

RESUMO Objetivo: conhecer os recursos generalizados de resistência das pessoas privadas de liberdade com hipertensão arterial sistêmica de uma região de tríplice fronteira. Método: pesquisa qualitativa pautada no referencial teórico da Salutogênese, da qual participaram 38 pessoas privadas de Liberdade de Foz do Iguaçu, Paraná, Brasil, no período de fevereiro a julho de 2022. Utilizou-se de questões norteadoras nas entrevistas, as quais foram submetidas a análise de conteúdo na modalidade temática. Resultados: emergiram 12 recursos generalizados de resistência nos relatos das pessoas presas com hipertensão arterial sistêmica: equipe de saúde; acesso às medicações; trabalho; hábitos de vida: alimentação, atividade física e restrição ao acesso a drogas/cigarro/bebida alcóolica; controle do estresse/ansiedade; leitura e jogos; religiosidade; família; autocuidado; companheiros de cubículo e funcionários. Conclusão: as pessoas privadas de liberdade com hipertensão arterial sistêmica apresentam recursos generalizados de resistência para manejar sua vida e saúde, os quais se relacionam ao cuidado pessoal, ao grupo social e ao ambiente. Destaca-se que, uma vez identificados, os recursos generalizados de resistência podem ser utilizados pelos profissionais de saúde no gerenciamento da HAS, outras doenças crônicas e promoção da saúde.

Clinical application of 3.0 T MR imaging without contrast in coronary artery based on compressed SENSE technology / 中华放射学杂志

Objective:To explore the optimal acceleration factor and feasibility of the compressed SENSE (CS) technique in non-contrast MR coronary angiography (NMRCA) for clinical practice.Methods:The image data of completed coronary CTA and 3.0 T NMRCA sequence in 31 patients with suspected coronary heart disease were prospectively recruited at Fuyang People′s Hospital from August 2021 to November 2021. NMRCA sequences included conventional SENSE2 sequence and CS sequences with acceleration factors of 4, 5, and 6, respectively. The subjective scores of image quality and the objective scores, the contrast ratios between assessed coronaries and myocardium (CMCR) were compared among the 4 groups using the Friedman and Wilcoxon rank sum test.Results:Compared with the conventional SENSE2 [(343±46)s], the scan time of CS4 (269±36), CS5 (214±29) and CS6 (178±26) s were shortened by 21.5%, 37.5% and 48.0%, respectively. There was a good consistency between the subjective scores of the four groups (Kappa=0.769, 95% Cl 0.738-0.800). There was no significant difference in subjective score and CMCR value between CS4 and SENSE2 ( P>0.05). The coronary artery segments of CS5 and CS6 were significantly different from SENSE2 group ( P<0.05). Conclusions:For 3.0 T NMRCA, CS technology shows high feasibility. The CS4 can reduce imaging time while ensuring high-quality coronary arterial images, which has a well-established clinical application value for NMRCA.

Relationship of latent classes of emotional behavior of children with mental disorders with sense of parenting competence and psychological distress of parents / 中华行为医学与脑科学杂志

Objective:To explore the latent classes of emotional behavior of children with mental disorders, and their relationship with parents' sense of parenting competence and psychological distress.Methods:A survey of 327 parents of children with mental disorders was conducted from September to December 2022 using the general information questionnaire, the sense of parenting competence scale, the Kessler psychological distress scale, and the strengths and difficulties questionnaire (parent version). Mplus 8.0 and SPSS 25.0 softwares were used for statistical analysis.The latent class analysis was used to identify subgroups of children with mental disorders based on their emotional behavior.Multinomial logistic regression was used to analyze the related factors.Results:Latent class analysis showed that the emotional behaviors of children with mental disorders were divided into 3 categories: emotion-conduct problem prominent group (38.53%(126/327)), simple emotional problem group (44.65%(146/327)), and emotion-peer interaction significant group (16.82%(55/327)). The differences among the 3 latent classes were statistically significant (all P<0.05) in terms of parents' parenting competence, satisfaction, and psychological distress scores.Compared with the emotion-conduct problem prominent group, the higher the parental parenting knowledge and parenting competence, the emotional behavior of children with mental disorders tended to be in the simple emotional problem group ( B=0.699, OR=2.011, 95% CI=1.046-3.868; B=0.088, OR=1.092, 95% CI=1.017-1.173). Compared with the " emotion-conduct problem prominent group" , the emotional behavior of children with mental disorders aged 13 to 18 years old tended to be in the " emotion-peer interaction significant group" ( B=1.982, OR=7.255, 95% CI=1.637-32.141). Conclusion:The emotional behavior of children with mental disorders is heterogeneous, and there are differences in sense of parenting competence and psychological distress of parents among different latent classes of children with mental disorders.

Promoting learning gains and practical ability of nursing students: the construction and empirical research of inquiry learning community / 中华医学教育探索杂志

Objective:To develop an inquiry learning community centered on learning experience in the course of Nursing Clinical Comprehensive Experiment to verify the influence of this teaching mode on the learning gains and practical ability of nursing students. Methods:A total of 132 undergraduate nursing students form grade 3 in Chongqing Medical University were enrolled. The participants were randomly assigned to a learning community group ( n = 69) and a control group ( n = 63) using Minitab 14.0 software. The students in the learning community group adopted the inquiry learning community mode in accordance with the curriculum map for online self-learning, group discussion and skills practice, while the control group received the teacher-led teaching mode for offline theory teaching, operation teaching and skills practice. After the teaching intervention, both groups of students received the assessment questionnaire of learning gains and the comprehensive experimental ability evaluation. Chi-square test or paired t-test was performed using SPSS 23.0. Results:Compared with the control group, students in the learning community group reported that their sense of learning gain was enhanced ( P<0.001, Cohen d=0.97); sub-items showed that the effect size for the understanding of learning content ( P<0.001, Cohen d=1.22), the overall course situation ( P<0.001, Cohen d=0.90), the course activities ( P=0.000, Cohen d=0.83), and the information obtained ( P<0.001, Cohen d=1.16) was significantly different. The total score of practical ability of comprehensive experiment was significantly improved ( P = 0.005, Cohen d=0.51), in which the experimental situation displays ( P=0.002, Cohen d=0.55) and experimental effect ( P=0.006, Cohen d=0.49) were better than the control group. There was no significant difference in the performance of experimental preparation and case analysis between the two groups. Conclusion:Developing an inquiry learning community in nursing clinical comprehensive experiment can effectively enhance student' sense of learning gains and promote the improvement of clinical practical ability.

Correlation analysis between family function and disease benefit in patients with chronic obstructive pulmonary disease / 中国实用护理杂志

Objective:To investigate and analyze the correlation between family function and disease benefit perception among patients with chronic obstructive pulmonary disease (COPD).Methods:A cross-sectional study, convenient sampling method, family function Assessment Scale (APGAR) and disease benefit scale were used to investigate the family function assessment and disease benefit of 172 COPD patients in the respiratory department of Yinchuan First People ′s Hospital from January to April 2021. Results:The total score of family function in COPD patients was (7.74 ± 2.50) points, and the total score of disease benefit was (53.24 ± 7.03) points. There was a positive correlation between family function and disease benefit in COPD patients ( r values were 0.041-0.275, P<0.05). Conclusions:The disease benefit of COPD patients was closely related to family function, and improving the level of family function support can improve the disease benefit of COPD patients.

Research on the Relationship between Metacognition and Self-directed Learning Ability of Undergraduate Nursing Students: A Moderated Mediation Model / 中国医学伦理学

【Objective:】 To explore the effect of metacognition on self-directed learning ability of undergraduate nursing students, and the role of interpersonal communication ability and sense of self-worth between them. 【Methods:】 A total of 905 undergraduate nursing students from six colleges and universities in Shaanxi were selected as the survey subjects by convenient sampling method during August to November 2022. Metacognitive Assessment Inventory, Self-Directed Learning Ability Measurement Scale for Nursing Students, Adolescent Sense of Total Self-Worth Scale, and Supportive Communication Scale were used to conduct a questionnaire survey on undergraduate nursing students. SPSS 25.0 software was used for statistical analysis of the data. 【Results:】 Finally, 854 valid questionnaires (94.36%) were collected, and the results showed that: a) Metacognition of undergraduate nursing students significantly positively predicted self-directed learning ability (β=0.172, P<0.001). b) Interpersonal communication ability played a partial mediating role between metacognition and self-directed learning ability [β=0.019, 95%CI: 0.004~0.034)] . c) The predictive effect of metacognition on self-directed learning ability was regulated by the level of self-worth (R2=0.314, P<0.001). 【Conclusion:】 This paper indicated that the metacognition of undergraduate nursing students indirectly affects their self-learning ability through interpersonal communication ability, and their sense of self-worth plays a moderating role. It is recommended to improve the metacognitive level of undergraduate nursing students, strengthen their interpersonal communication skills, and focus on the cultivation of self-worth, so as to improve their self-directed learning ability.

Psychological status and correlation between anxiety and science literacy of medical staff under the public health emergency / 四川精神卫生

BackgroundIn public health emergencies， medical staff undertake many important tasks. Having a good mental health status and capability in popularization of science can improve the work efficiency of medical staff， and thus enhancing the public's trust and support for medical care. ObjectiveTo investigated the anxiety， insomnia and security level of medical staff under the public health emergency， and to explore the correlation between anxiety and capability in popularization of science of them. MethodsFrom June 1 to September 1， 2020， a total of 588 medical staff in Sichuan Province were investigated through the Questionnaire Star platform. The survey included a self-designed general information questionnaire， the Psychological Security-Insecurity Questionnaire （S-I）， Self-rating Anxiety Scale （SAS）， Athens Insomnia Scale （AIS） and science popularization questionnaire during the COVID-19 epidemic. Pearson correlation analysis was used to examine the correlation among SAS， S-I and AIS scores， as well as the correlation between SAS and the science popularization questionnaire during the COVID-19 epidemic. ResultsDuring the public health emergency， the S-I score of the medical staff was （27.46±9.20）， with 21 cases （3.57%） having a low level of security. The SAS score was （44.21±9.57）， with 208 cases （35.37%） having anxiety symptoms. The AIS score was （11.40±5.25）， with 450 cases （76.53%） suffering from insomnia. Correlation analysis showed that SAS score was negatively correlated with S-I score （r=-0.640， P<0.01）， while positively correlated with AIS score （r=0.618， P<0.01）. There was a negative correlation between the degree of usage about medical staff's science popularization tool and SAS score （r=-0.501~-0.185， P<0.01）. The use of science popularization channels was negatively correlated with anxiety （r=-0.510~-0.232， P<0.05 or 0.01）. There was a negative correlation between the level of trust to popularization of science and medical staff anxiety （r=-0.548~-0.338， P<0.01）. ConclusionUnder the public health emergency， the detection rates of anxiety symptoms and sleep disorders among medical staff are high， and anxiety is negatively correlated with medical staff's capability in popularization of science. ［Funded by Sichuan Mianyang Psychological Growth Guidance and Research Center for Minors Funded Project （number， SCWCN2020YB11）］.

Medical Student-led Activities to Listen to Patients' Narratives and Laugh at Each Other / 日本プライマリ・ケア連合学会誌

We organized regular, student-led activities in which medical students listened to patients' narratives and engaged in casual conversation. This report reviews these activities, which were conducted 28 times between June 2020 and September 2022. Through the activities, we received feedback on feelings, new perspectives, and realizations that arose from both students and patients. Our findings suggest that listening to patients' narratives helped students self-reflect and understand the patients' perspectives. Moreover, interacting with students helped patients feel a sense of meaning and a new understanding of their illness.

The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses

Positive-sense RNA viruses modify intracellular calcium stores, endoplasmic reticulum and Golgi apparatus (Golgi) to generate membranous replication organelles known as viral factories. Viral factories provide a conducive and substantial enclave for essential virus replication via concentrating necessary cellular factors and viral proteins in proximity. Here, we identified the vital role of a broad-spectrum antiviral, peruvoside in limiting the formation of viral factories. Mechanistically, we revealed the pleiotropic cellular effect of Src and PLC kinase signaling via cyclin-dependent kinase 1 signaling leads to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (GBF1) phosphorylation and Golgi vesiculation by peruvoside treatment. The ramification of GBF1 phosphorylation fosters GBF1 deprivation consequentially activating downstream antiviral signaling by dampening viral factories formation. Further investigation showed signaling of ERK1/2 pathway via cyclin-dependent kinase 1 activation leading to GBF1 phosphorylation at Threonine 1337 (T1337). We also showed 100% of protection in peruvoside-treated mouse model with a significant reduction in viral titre and without measurable cytotoxicity in serum. These findings highlight the importance of dissecting the broad-spectrum antiviral therapeutics mechanism and pave the way for consideration of peruvoside, host-directed antivirals for positive-sense RNA virus-mediated disease, in the interim where no vaccine is available.