ABSTRACT
BackgroundThe cardiovascular disease is leading cause of mortality and constantly increasing every year forpast decades. In 2014, cardiovascular diseases were the leading cause of NCD deaths (17.5 milliondeaths) [7] In Mongolia cardiovascular disease is also leading the cause of mortality and morbidity.It is increasing every year, 479.4 per 10000 population in 2012 was increased to 848.1 per 10000population in 2013 [1, 2].Dr.Jerardin, prof. Z.Lkhagvasuren implanted first stent in Mongolia in 2000. There is rapiddevelopment in interventional cardiology treatment since then.Material and MethodsSince 2011 until 2015, total of 4545 coronary angiography, 2322 stent implantation was performed.This study has included the patients of last 5 years. Total of 1257 patients who were treated with AMIduring 2011 to 2015 at the Third central State Hospital were analyzed.Results73.7% of the patients had left coronary artery disease and 26.3% had right coronary artery disease.Tis findings were similar with other local researcher’s study [3, 4].59.4% of the occlusions were 75-99% stenosis, 23.5% had total occlusion. 62.9% of LAD occlusionwere stenosis over 75%. It demonstrated majority of cases performed were high severe lesions. Thisalso may be demonstrating that patients are receiving treatment in their late stage of the disease.Every stage complication such as mortality, was 3.5%, complication such as restenosis followingone month of after stent implantation was 9-13.1%. Overall mortality rate has decreased each year,11.9% in 2011, 7.8% in 2012, and 4.6% in 2013 relatively. General achievement is now 88.1-95.4%,which is comparable to other countries.Conclusion1257 patients presented with acute myocardial infarction were studied: 880 (70, 0%) were male, 377(30, 0%) were female. Mean age of patients was 55, 08±1, 23; it was 75 patients had no risk factors,751 patients with 1-2 risk factors, 431 patients with 3 or more risk factors. Angiographic distributionof lesion shows 74, 4% had LAD disease, 64, 5% had RCA disease, 25, 8% had LCX lesion, 12, 9%had dialonal LCA lesion.
ABSTRACT
Background & Objectives: 1} To describe thyroid hormone profile in patients with acute coronary syndromes (ACS) 2} To find, If any, short term prognostic significance of Thyroid diseases. Materials & Methods The study has been carried out at Shree Sayajirao General Hospital and Medical College Baroda during period of March 2011 to May 2012. The study comprised of patients with acute coronary syndrome admitted in ICCU of SSG, Hospital. Inclusion criteria were patients with acute coronary syndrome, irrespective of gender, race, ethnic group, age, and clinical severity, giving consent for being included as a part of the study. Exclusion criteria included patients using corticosteroids, amiodarone, or thyroid disease drugs, who had received any iodinated contrast agent within the previous two weeks, Patients with established diseases, such as neoplasias, chronic renal failure, chronic obstructive pulmonary disease requiring antibiotic therapy, liver cirrhosis, active infection, and decompensated diabetes mellitus, conditions that are known to affect thyroid function tests. Results: Of total 30 pts of STEMI, 30 % had increased level of Free T4 on day 0 and 23.07% had increased values on day 4. Of total 30 pts of NSTEMI/UA, 20 % had increased level of Free T4 on day 0 and 14.28% had increased values on day 4. The levels of TSH, free and Total T3 as well as Total T4 were not significantly different in either STEMI/NSTEMI group either Day 0 or Day 4. 21.67% of pts had evidence of Sick Euthyroid Syndrome on day of admission. Of the total 6 pts expired before day 4, 3 patients had evidence of Sick Euthyroid Syndrome at the time of admission. The association of Sick Euthyroid syndrome was found to be significant for mortality in patients of STEMI with 3 out of 4 expired patients of STEMI having SES at the of admission with significant p value {p <0.05} .There was no significant difference in mortality in patients of NSTEMI/UA having SES. Conclusion: Our results show the importance of recognizing the “Euthyroid Sick Syndrome” in coronary heart disease patients, suggesting an association with poorer prognosis in patients with ST elevated Myocardial Infarction in form of increased mortality and no association was found with mortality in patients having Non ST elevated Myocardial Infarction or Unstable Angina.