Sexually transmitted infections lesions found during colonoscopies

Introduction: Anal examination and videoanoscopy (VA) are rarely performed during colonoscopies. In recent years, there has been a considerable increase in lesions of sexually transmitted anal and rectal infections, but these conditions are not noticed or reported during routine colonoscopy. Objective: To raise awareness regarding the fortuitous findings of lesions and sexually transmitted infections (STIs) in colonoscopy exams and to demonstrate that anal examination and VA provide important information and should be routinely performed. Methods: We conducted a descriptive retrospective study in 16,132 patients screened by colonoscopy and VA between 2006 and 2018. Among numerous other findings, the presence of anal condylomata and sexually transmitted retitis or perianal dermatitis was observed. The rates of each finding were calculated, and the patients were subdivided by sex and into age groups by blocks of ten years. Results: Among the 16,132 colonoscopies performed, 26 cases of condyloma (0.16%) and 50 cases of proctitis or perianal dermatitis suspicious for STI (0.33%) were found. Conclusion: Performing anal examination and VA systematically in all routine colonoscopies enabled the identification of numerous anal conditions, including several fortuitous cases of STIs. The study proposes that anal examination and VA should be performed in all routine colonoscopies and, in suspected cases, complementary tests for STIs. (AU)

Mulheres que fazem sexo com mulheres na juventude e a prevenção de infecções sexualmente transmissíveis: um estudo de representações sociais / Women who have sex with women in youth: the prevention of sexually transmitted infections: a study of social representations

Este estudo teve o objetivo de analisar as representações sociais de mulheres que fazem sexo com mulheres (MSM) sobre as infecções sexualmente transmissíveis (IST) e as práticas de prevenção, e tem como um dos objetivos específicos, discutir as relações estabelecidas entre as representações sociais de MSM sobre as IST e as práticas de prevenção. Trata-se de um estudo descritivo, qualitativo, com abordagem qualitativa, ancorado na abordagem estrutural da Teoria das Representações Sociais. Participaram 100 jovens mulheres homossexuais, moradoras do município do Rio de Janeiro, na faixa etária entre 18 e 29 anos. Foram aplicados dois instrumentos de coleta de dados, um questionário para caracterização sociodemográfica, das práticas sexuais e de prevenção de IST; e um formulário para captação das evocações livres, com os termos indutores DST e Prevenção de DST. Os dados sociodemográficos foram organizados no software Excel. A análise das evocações foi feita através do software EVOC com a construção do quadro de quatro casas. Para o termo indutor DST, os possíveis núcleos centrais foram os cognemas sexo, doenças, prevenção e sífilis. A palavra sexo teve a maior frequência e foi a mais prontamente evocada no núcleo central, demonstrando a relevância da palavra para o grupo investigado, no entanto, as palavras relacionadas a ela se concentraram na zona de contraste e segunda periferia. Na análise de similitude, esse elemento estabeleceu conexões com todos os elementos da árvore, e teve o maior número de ligações (cinco). O termo indutor Prevenção de DST teve somente o cognema preservativos no provável núcleo central e sete nas periferias, onde mencionaram cuidado, relacionamento-afetivo, tratamento, entre outros relacionados ao autocuidado, sugerindo um imaginário alinhado com a temática. Já na análise de similitude pode-se notar que o termo preservativos é central e apresenta sete ligações com os demais termos presentes no quadro, tendo maior índice as ligações com os termos cuidado, exames, relacionamento-afetivo e informação. Conclui-se que, apesar de as jovens demonstrarem conhecimento acerca da temática, informaram o desuso do preservativo nas relações sexuais com parcerias fixas e casuais, corroborando com outras investigações. Ademais, apesar de reconhecerem a maioria das IST, o termo HPV que é uma infecção recorrente nesse grupo, foi mais tardiamente evocado pelas participantes. Desse modo, é notória a importância da disseminação de informação acerca da prevenção das IST nesse grupo, como também para os profissionais de saúde, que, em geral, possuem um comportamento heteronormativo nos atendimentos às mulheres lésbicas, subestimando o potencial de contaminação que pode existir nas relações homossexuais entre mulheres.

This study aimed to analyze the social representations of women who have sex with women (WSW) about sexually transmitted infections (STIs) and prevention practices, and has as one of the specific objectives, to discuss the relationships established between the social representations of WSW about STIs and prevention practices. This is a descriptive, qualitative study with a qualitative approach, anchored in the structural approach of the Theory of Social Representations. 100 young people participated, all homossexual women, living in the city of Rio de Janeiro, aged between 18 and 29 years. Two data collection instruments were applied, a questionnaire for sociodemographic characterization, sexual practices and STI prevention; and a form to capture the free evocations, with the terms STD inducers and STD Prevention. The sociodemographic data were organized in Excel software. The analysis of the evocations was made through the EVOC software with the construction of the frame of four houses. For the term STD inducer, the possible central nuclei were the cognames sex, diseases, prevention and syphilis. The word sex had the highest frequency and was the most readily evoked in the nucleus central, demonstrating the relevance of the word for the investigated group, however, the words related to it focused on the contrast zone and second periphery. In similitude analysis, this element established connections with all the elements of the tree, and had the highest number of calls (five). The inducing term STD Prevention had only the cognama condoms in the probable central nucleus and seven in the peripheries, where they mentioned care, affective relationship, treatment, among others related to self-care, suggesting an imaginary aligned with the theme. As for the analysis of similarity, it can be noted that the term condoms is central and has seven links with the other terms presente in the table, with a higher index of links with the terms care, examinations, relationship-affective and information. It is concluded that, although the young women demonstrate knowledge. On the subject, they reported the disuse of condoms in sexual relations with partners fixed and casual, corroborating with other investigations. Moreover, although they recognize the most STIs, the term HPV which is a recurrent infection in this group, were more belatedly evoked by the participants. Thus, the importance of dissemination of information about the prevention of STIs in this group, as well as for the health professionals, who, in general, have a heteronormative behavior in the care for lesbian women, underestimating the potential for contamination that can exist in homosexual relations between women.

Analysis of Sexually Transmitted Infections Prevention Campaigns between 2008 and 2020 / Análise de Campanhas Preventivas a Infecções Sexualmente Transmissíveis entre 2008 e 2020

Abstract This study aimed to analyze the sexually transmitted infections (STIs) prevention campaigns promoted by the Brazilian Ministry of Health between 2008 and 2020. Fifty-three campaigns from the digital archive were included in the directed content analysis. The analysis was conducted based on the concepts of Combination Prevention and the Theory of Planned Behavior (TPB). Condom use and STI testing were constantly promoted, to the detriment of alternative preventive behaviors. The TPB concepts in the campaigns suggest the compatibility of the materials with the theory. We conclude that the campaigns present the desirable aspects of prevention. However, recent campaigns focused on aversive materials, which goes against studies that report negative effects from these strategies and is associated with the rise of moralist perspectives on prevention.

Resumo Objetivou-se analisar as campanhas de prevenção a infecções sexualmente transmissíveis (ISTs) veiculadas pelo Ministério da Saúde entre 2008 e 2020. Cinquenta e três campanhas disponíveis no acervo digital foram incluídas na análise de conteúdo dirigida. A análise foi realizada com base nos conceitos da Prevenção Combinada e da Teoria do Comportamento Planejado (TCP). O uso de camisinha e a realização de testagem para ISTs foram constantemente promovidos, em detrimento de comportamentos preventivos alternativos. Os conceitos da TCP nas campanhas indicam compatibilidade dos materiais com pressupostos teóricos. Conclui-se que as campanhas abordam os aspectos desejáveis da prevenção. Contudo, as campanhas mais recentes investiram em materiais aversivos, estratégia contraindicada por outros estudos, porém associada ao crescimento da perspectiva moralista de prevenção.

Ressecção endoscópica de extensa lesão condilomatosa uretral ­ relato de caso e revisão da literatura / Endoscopic resection of extensive urethal condilomatic injury - case report and literature review

Introdução: O Condiloma uretral é uma infecção sexualmente transmissível comum associada ao vírus do papiloma humano. O acometimento na uretra é raro, principalmente quando trata-se de um paciente HIV positivo com carga viral indetectável. Objetivo: Tem como objetivo discutir sobre o acometimento uretral do papiloma vírus e as possíveis formas de tratamento, assim como revisar a literatura. Relato de caso: O paciente em questão apresentou suspeita de carcinoma de células de transição, sendo encaminhado para tratamento, porém afastado essa suspeita e fechando diagnóstico para lesão condilomatosa uretral, sendo realizado tratamento por ressecção endoscópica das lesões com energia monopolar. Discussão: O acometimento uretral ocorre em até 5% dos casos, e o mesmo apresenta alta probabilidade de malignização. Não existem diretrizes específicas sobre o manejo do condiloma intra-uretral, pois trata-se de uma patologia rara. O objetivo dos tratamentos é remover as verrugas e induzir períodos livre de lesões, sendo que o conservador com crioterapia e o ácido tricloroacético nem sempre são aplicáveis à uretra devido ao difícil acesso. A ressecção endoscópica das lesões tem se mostrado mais eficaz. Conclusão: Urologistas e patologistas devem estar cientes dessa rara possibilidade, a fim de evitar erros de diagnóstico acerca dessa entidade predominantemente benigna. Desta forma apresentamos um caso de ressecção endoscópica de extensa lesão condilomatosa em uretra peniana de uma paciente masculino hemofílico e HIV positivo. [au]

Introduction: Urethral condyloma is a common sexually transmitted infection associated with the human papillomavirus (HPV). Affection in the urethra is rare, especially when dealing with an HIV positive patient with an undetectable viral load. Objective: It aims to discuss the urethral involvement of the papillomavirus and the possible forms of treatment, as well as to review the literature. Case report: The patient in question presented suspicion of transitional cell carcinoma, being referred for treatment, but this suspicion was removed and the diagnosis of urethral condylomatous lesion was closed, with treatment by endoscopic resection of the lesions with monopolar energy. Discussion: Urethral involvement occurs in up to 5% of cases, and it has a high probability of malignancy. There are no specific guidelines on the management of intra-urethral condyloma, as it is a rare condition. The goal of treatments is to remove warts and induce injury-free periods, the conservative with cryotherapy and trichloroacetic acid not always being applicable to the urethra due to difficult access. Endoscopic resection of the lesions has been shown to be more effective. Conclusion: urologists and pathologists should be aware of this rare possibility, in order to avoid diagnostic errors about this predominantly benign entity. Thus, we present a case of endoscopic resection of an extensive condylomatous lesion in the penile urethra of a male patient with hemophilia and HIV positive. [au]

Experiencias y percepciones sobre sexualidad, riesgo y campañas de prevención de ITS/VIH por estudiantes universitarios. Diseñando una intervención digital / Experiences and perceptions on sexuality, risk and STI/HIV prevention campaigns by university students. Designing a digital intervention

Resumen Damos cuenta de la fase cualitativa de una investigación que busca diseñar una intervención digital de prevención de ITS/VIH y promoción de salud sexual en jóvenes universitarios. A partir de grupos focales se abordó la experiencia y percepción que universitarios tienen sobre sexualidad, riesgo y campañas de prevención. Se realizan entrevistas semiestructuradas a informantes claves. Los resultados muestran que la educación sexual es escasa, reducida a lo biológico, cargada de prejuicios y sesgos de género, limitando el manejo de información por la población estudiantil. Se evidencian estrategias vacilantes de prevención, no logrando motivar ni ofrecer oportunidades para la toma de decisiones conscientes y autónomas en salud sexual. Las campañas de ITS/VIH se evaluaron poco inclusivas, lejanas y basadas en el miedo. Las intervenciones en salud sexual han fallado en sopesar aspectos experienciales de la sexualidad juvenil, basándose en modelos de comportamiento ideal y estereotipado, desechando narrativas en primera persona y su rica complejidad. Es imperativo innovar en la prevención de ITS/VIH, formulando intervenciones basadas en un diseño integrador, multidisciplinar y situado, que valore la teoría y la experiencia de las poblaciones objetivo.

Abstract This study reports on the qualitative phase of a study that seeks to design a digital intervention for the prevention of STI / HIV and promotion of sexual health in university students. The experience and perception that university students have about sexuality, risk and prevention campaigns are addressed through focus groups. Semi-structured interviews are conducted with key informants. The results reveal that sexual education is limited and restricted to the biological aspect, as well as loaded with prejudices and gender biases, which narrows the information provided to the student population. Wavering prevention strategies that fail to motivate students or offer them opportunities for making informed and independent decisions about their sexual health are apparent. The STI / HIV campaigns assessed are distant, fear-based and not inclusive. Interventions in sexual health do not weigh experiential aspects of youth sexuality, as they are based on models of ideal and stereotyped behavior, discarding first-person narratives and their rich complexity. It is imperative to innovate in the prevention of STI/HIV, formulating interventions based on an integrative, multidisciplinary and contextualized design that values the theory and experience of the target populations.

Qualidade da comunicação promotora da saúde: como avaliar? Proposta de instrumento de avaliação de campanhas de prevenção de infecções sexualmente transmissíveis (ISTs) / Evaluating the effectiveness of health communication: a proposed tool for evaluating sexually transmitted infections (STI) prevention campaigns / Calidad de la comunicación promotora de la salud: ¿cómo evaluarla? Propuesta de instrumento de evaluación de campañas de prevención de infecciones de transmision sexual (ITSs)

O que pode ser considerado comunicação de qualidade para a promoção da saúde e da prevenção de ISTs entre jovens? Este artigo apresenta uma proposta de metodologia de pesquisa para avaliar a qualidade de peças produzidas no contexto de campanhas de comunicação pública, tais como vídeos, cartazes, folhetos, mídias sonoras e impressas, postagens em redes sociais on-line etc. Os indicadores utilizados para determinar parâmetros de qualidade foram extraídos da literatura especializada e sistematizados em um roteiro de avaliação, com sete blocos temáticos articulados em torno de proposições normativas. Neste artigo, caracterizamos tal roteiro, sua fundamentação e sua forma de aplicação, que buscam responder ao desafio de determinar o que é qualidade em teoria e prática na comunicação promotora da saúde. Trata-se de um instrumento objetivo sobre corpora extensos que pode ser aplicado por pesquisadores individuais ou equipes.(AU)

What constitutes effective communication for health promotion and the prevention of STI among young people? This article proposes a methodology for evaluating the effectiveness of public publicity campaign pieces, such as videos, posters, leaflets, audio and print media, and social media posts. The indicators used to determine effectiveness were taken from the specialist literature and systematized in the form of an evaluation guide consisting of seven thematic blocks structured around normative propositions. This article describes the guide, the rationale behind it, and its application as a health communication tool for determining effectiveness in theory and practice. The guide provides an objective tool that can be applied by individual researchers or teams to a broad range of corpora.(AU)

¿Qué es lo que puede considerarse comunicación de calidad para la promoción de la salud y de la prevención de ITSs entre jóvenes? Este artículo presenta una propuesta de metodología de investigación para evaluar la cantidad de piezas producidas en el contexto de campañas de comunicación pública, tales como videos, carteles, folletos, medios sonoros e impresos, posteos en redes sociales online etc. Los indicadores utilizados para determinar parámetros de calidad se extrajeron de la literatura especializada y se sistematizaron en un guion de evaluación, con siete bloques temáticos articulados alrededor de propuestas normativas. En este artículo, caracterizamos ese guion, su fundamentación y forma de aplicación, que buscan responder al desafío en la comunicación promotora de la salud, de determinar lo que es calidad en teoría y práctica. Se trata de un instrumento objetivo y que pueden aplicarlo investigadores individuales o equipos sobre corpus extensos.(AU)

Clínica psicológica ampliada em IST/HIV-Aids: sentidos produzidos por psicólogas no SUS / Amplified clinic in STI/HIV-AIDS: meanings produced by psychologists in Brazilian health public system (SUS) / Clínica psicológica ampliada en ITS/VIH-sida: sentidos producidos por psicólogas en el sistema único de salud (SUS)

Este estudo buscou compreender as práticas discursivas de psicólogas(os) sobre a atuação psicológica na abordagem às IST/HIV-Aids em serviços especializados em uma cidade da Bahia. Para tanto, foram realizadas nove entrevistas semiestruturadas com profissionais ligadas(os) a serviços da rede pública de saúde. A perspectiva teórico-metodológica da psicologia social construcionista inspirou o processo de produção e análise das informações. Os resultados apontaram para importantes rupturas e ressignificações dos repertórios linguísticos gestados no cotidiano das práticas em saúde (tempo vivido e tempo curto), em atenção às necessidades dos contextos de atuação, ainda que elementos da formação clássica da psicologia também sejam utilizados para caracterizar a atuação nesses espaços. Nos serviços pesquisados, as(os) psicólogas(os) têm conseguido enxergar e reconhecer demandas de ordens biológica e social, que indicam aspectos objetivos da vivência dos(as) usuários(as) (menos afeitos ao ideário individualista), apontando para uma contextualização da clínica psicológica no campo da saúde pública, embora nem todas(os) admitam que essas demandas devam ser cuidadas também pela(o) profissional de psicologia. Do ponto de vista teórico, partimos de reflexões sobre as noções de clínica ampliada e de atuação psicológica coletiva até alcançarmos a noção de clínica psicológica ampliada, situada em relação às especificidades da atuação psicológica no campo do HIV-Aids. Nessa direção, a clínica psicológica ampliada apresenta-se em potencial construção, situando-se entre aproximações e recuos do que seria uma prática desenvolvida de modo contextualizado e comprometido com os processos subjetivos de pessoas vivendo com HIV-Aids ou tentando se proteger em situações concretas de vulnerabilidade, que geram sofrimento psicossocial.(AU)

This study aimed to understand the discursive practice of psychologists regarding the psychological practice in the approach to STI/HIV-AIDS in specialized services in a city of Bahia. To do so, we conducted nine semi-structured interviews with professionals related to health public services. The theoretical-methodological perspective of social constructionist psychology inspired the process of information production and analysis. The results pointed towards important ruptures and resignifications of the linguistic repertoires created in the everyday health practices (lived time and short time), attentive to the needs of the contexts of practice, although elements of traditional psychology training are also used to characterize the work in these contexts. In the surveyed services, the psychologists have been noticing and recognizing biological and social demands, which indicate objective aspects of the users' experience (less adept to individualistic values). This fact points towards a contextualization in the psychological work in the public health field, although not all interviewed psychologists admit that this type of demand should also be addressed by psychology professionals. From a theoretical point of view, we started from reflections on the notions of amplified clinic and the collective psychological practice resulting in the concept of amplified psychological clinic that relates to specificities of the psychological work in the field of HIV-AIDS. In this respect, the amplified psychological clinic is in potential construction, approaching and retreating from what would be a developed practice contextualized and committed to the subjective processes of people living with HIV-AIDS or trying to protect themselves in concrete vulnerable situations, which produces psychosocial suffering.(AU)

Este estudio pretende comprender las prácticas discursivas de psicólogas/os sobre la acción psicológica para abordar las infecciones de transmisión sexual y el sida (ITS/VIH-sida) en servicios asistenciales especializados en una ciudad de Bahía (Brasil). Con este fin, se realizaron nueve entrevistas semiestructuradas con profesionales vinculados a los servicios de salud pública. La perspectiva teórico-metodológica de la psicología social construccionista inspiró el proceso de producción y análisis de datos. Los resultados apuntaron a importantes rupturas y resignificaciones de los repertorios lingüísticos producidos en la práctica diaria de la salud (tiempo vivido y tiempo corto), atentos a las necesidades de los contextos de acción, aunque también se utilizan elementos de la formación clásica de la psicología para caracterizar la práctica en esos espacios. En los servicios investigados, las/los psicólogas/os han podido ver y reconocer las demandas y sus dimensiones biológicas y sociales, que indican aspectos objetivos de la experiencia de los/as usuarios/as (poco afectados por los ideales individualistas), apuntando a una contextualización de la clínica psicológica en el contexto de la salud pública, aunque no todos admiten que estas demandas también deban ser atendidas por el profesional de la psicología. Del punto de vista teórico, partimos de reflexiones sobre las nociones de clínica ampliada y acción psicológica colectiva hacia llegar a la noción de clínica psicológica ampliada, situada en la relación con las especificidades de la acción psicológica en el campo del VIH/sida. En ese sentido, la clínica psicológica ampliada es una potencial construcción, que tiene lugar entre aproximaciones y retrocesos de lo que sería una práctica desarrollada de manera contextualizada y comprometida con los procesos subjetivos de las personas que viven con VIH/sida o que intentan protegerse en situaciones concretas de vulnerabilidad, que generan sufrimiento psicosocial.(AU)

Knowledge and practices of female students at University of Kara regarding sexually transmitted infections in Togo, 2021

A good knowledge of sexually transmitted infections (STI) in female students is an important element in the prevention of STI transmission. The objective of this study is to describe the level of knowledge and practices on STI among female students at the University of Kara. A cross-sectional study was conducted at the University of Kara from July to September 2021. Data were collected using a standard, digitalised, selfadministered questionnaire. Logistic regression analysis was used to describe factors associated with the level of knowledge of STIs. A total of 1,055 female students with a median age of 21 years (interquartile range: 20-24) participated in the study. More than one-third (33.7%) of the students had good knowledge of STI. Having already been tested for HIV (aOR=3.25; 95% CI 2.36-4.52), having already had sex (aOR=1.56; 95% CI 1.10-2.24) and the level of education (AOR=3.46; 95% CI 2.10-5.85) were significantly associated with good STIs knowledge. Among the 723 female students (68.5%) who already had sex, 32.5% reported inconsistent use of condoms during sexual intercourse and 18.9% reported having multiple sexual partners. The results of this study highlight the importance of intensifying STIs prevention efforts (awareness, screening, and vaccination) among female students at the University of Kara.

Three-dimensional speckle tracking imaging for quantitative evaluation of left ventricular global strain in renal transplant recipients / 器官移植

Objective To evaluate the application value of three-dimensional speckle tracking imaging (3D-STI) in quantitatively evaluating the left ventricular global strain in recipients within 3 months after renal transplantation. Methods Clinical data including blood pressure, serum creatinine and tacrolimus blood concentration of 34 renal transplant recipients were collected before operation, 7 d, 1 month and 3 months after operation, respectively. Meanwhile, conventional echocardiography and 3D-STI examination were performed. Echocardiographic parameters [left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF)] and 3D-STI parameters [left ventricular global peak longitudinal strain (GPLS), global peak circumferential strain (GPCS), global peak radial strain (GPRS) and global peak area strain (GPAS)] of recipients were collected. The changes of these parameters before operation, 7 d, 1 month and 3 months after operation were statistically compared. The changing characteristic and application value of 3D-STI in quantitatively evaluating the left ventricular global strain in recipients within 3 months after renal transplantation were evaluated. Results LVEF and GPCS did not significantly differ at different time points (all P > 0.05), whereas LVEDV, LVESV, GPLS, GPAS and GPRS significantly differed at different time points from preoperative to within postoperative 3 months (all P < 0.001). GPLS, GPAS and GPRS trended to decline within postoperative 1 month, and slightly increased at 3 months after operation, which was still lower than the preoperative levels. Conclusions Application of 3D-STI may sensitively detect the changes of left ventricular global strain in recipients after renal transplantation when no significant variations are observed in postoperative LVEF. Compared with conventional echocardiography, 3D-STI may more accurately evaluate the changes of left ventricular global strain in recipients after renal transplantation.

Transmisión sexual del virus SARS-CoV-2 y su rol en la propagación de COVID-19: protocolo de una revisión sistemática viva / Sexual transmission of SARS-CoV-2 virus and its role in the spread of COVID-19: a living systematic review protocol

Objetivo Proporcionar una revisión de la literatura sobre la presencia de SARS-CoV-2 en los fluidos sexuales de pacientes con COVID-19 y su posible transmisión sexual de manera oportuna, rigurosa y continuamente actualizada. Fuentes de datos Realizaremos búsquedas en PubMed / Medline, Embase, Registro Cochrane Central de Ensayos Controlados (CENTRAL), literatura gris y en un repositorio centralizado en L · OVE (Living OVerview of Evidence). L · OVE es una plataforma que mapea las preguntas PICO a la evidencia de la base de datos Epistemonikos. En respuesta a la emergencia de COVID-19, L · OVE se adaptó para ampliar el rango de evidencia que cubre y se personalizó para agrupar todas las pruebas de COVID-19 en un solo lugar. La búsqueda cubrirá el período hasta el día anterior al envío a una revista. Criterios de elegibilidad para la selección de estudios y métodos Adaptamos un protocolo común ya publicado para múltiples revisiones sistemáticas paralelas a las especificidades de esta pregunta. Incluiremos ensayos aleatorios que evalúen la transmisión sexual del virus SARS-CoV-2. Se buscarán ensayos aleatorizados que evalúen la transmisión sexual de otros coronavirus, como MERS-CoV y SARS-CoV, y estudios no aleatorizados en COVID-19 en caso de que no se encuentre evidencia directa de ensayos aleatorizados, o si la evidencia directa proporciona una - o certeza muy baja para resultados críticos. Dos revisores evaluarán de forma independiente la elegibilidad de cada estudio, extraerán datos y evaluarán el riesgo de sesgo. Realizaremos metanálisis de efectos aleatorios y utilizaremos GRADE para evaluar la certeza de la evidencia para cada resultado. Una versión viva basada en la web de esta revisión estará disponible abiertamente durante la pandemia de COVID-19. Lo volveremos a enviar si las conclusiones cambian o hay actualizaciones sustanciales Registro PROSPERO (CRD42020189368).

Impact of Comprehensive HIV/AIDS Prevention Program on Reduction of Risky Sexual Behaviors in an African Rural Community

Aims: This study compares the sexual behaviour of the residents of Bonny kingdom, Rivers Statein pre-intervention and post-intervention periods of a comprehensive HIV/AIDS prevention program carried out by the African Health Project in collaboration with independent research consultants and members of the Ibanise HIV/AIDS initiative in the community for three years from 2009-2012.Methodology:This is a quantitative survey that used a structured questionnaire among a representative sample of the general population aged 15 –49 years. Post-intervention survey was conducted three years after the pre-intervention survey. The data obtained include the demographics; age, sex, education, occupation, marital status and sexual related information. Data were analyzed using SPSS version 25.0.Results:This study comprised 1021 (53.3%) males and 895 females (46.7%) in the pre-intervention survey and 659 (54.2%) malesand 556 (45.7%) in the post-intervention survey, mostly aged 15-34 years and had secondary education. More females have ever had sex in both surveys but there was a significant reduction in the percentage of males who have ever had sex from 70.8% to 42.0%in pre-intervention and post-intervention surveys respectively. The rate of sexual activities was very high before intervention among unmarried males (51.6%), age 15-24 years (69.6%), secondary education (50.7%) and graduates (65.9%). However, there was adrastic reduction in these values after the interventions. During pre-intervention survey, 9.4% of females and 13% of males had ever accepted or given gifts exchange for sex while the post-intervention survey showed a decrease into 8.0% among females and 5.5% among males. This proportion was 13.0% among adolescents 15-24 years in the pre-intervention survey and 4.7% in the post-intervention survey. Also, there was 65.0% decrease in the proportion of singles who had ever received gifts in exchange for sexual intercourse after the intervention. A high proportion of the males had multiple sexual partners during the pre-intervention survey (34.6%) but the value reduced to 3.2% after the intervention. Similarly, the percentage of the adolescent who had multiple sexual partners reduce from 22.2% to 2.5% due to the intervention. The pre-intervention survey showed that about 56.0% of males and 81.0% of females had sex with non-marital partners while the post-intervention survey showed that about 71.0% of males and 76.0% of females did same.Conclusion:The study has shown a significant positive impact of health interventions in improving the sexual behaviour of Bonny residents. However, more and regular interventions are needed in this environment to further prevent the spread of HIV and STIs due to the vulnerability of the residents, especially the adolescents to sexually transmitted infection.There is also need for more study to evaluate the impact of sexual and reproductive health programs for adolescence and adultthat already exist in Nigeria in comparison with the HIV intervention outcome.

(In)visibilidade lésbica na saúde: análise de fatores de vulnerabilidade no cuidado em saúde sexual de lésbicas / Lesbian health (In)visibility: analysis of vulnerability factors in lesbian sexual health care / (In)visibilidad de la salud de las lesbianas: análisis de los factores de vulnerabilidad en el cuidado de la salud Sexual de Lesbianas

Resumo O presente estudo teve como objetivo geral analisar a vulnerabilidade em saúde sexual e as práticas preventivas frente a infecções sexualmente transmissíveis (IST) nas relações afetivo-sexuais de lésbicas. Tratou-se de um estudo exploratório e descritivo, de caráter transversal e qualitativo. A amostra foi composta por 18 participantes mulheres, brasileiras, que se autodefinem lésbicas, com idades variando de 19 a 42 anos (M = 26; DP = 6,1). Para a coleta dos dados, foram utilizados um questionário sociodemográfico e entrevistas semiestruturadas. Os dados foram analisados por meio da análise categorial temática. Foram evidenciados que os supostos métodos existentes não seriam próprios, específicos ou pensados para a prevenção às IST entre mulheres, tendo em vista que a maioria destes meios de prevenção seriam adaptações de métodos já existentes ou adaptações de itens que originalmente seriam utilizados com outras finalidades. Conclui-se que elementos de ordem programática parecem influenciar de maneira mais intensa para a situação de maior vulnerabilidade à saúde das lésbicas, embora estes também estejam relacionados a elementos individuais e sociais.

Abstract This study analyzed the vulnerability in sexual health and preventive practices regarding Sexually Transmitted Infections (STIs) in the affective-sexual relationships of lesbians. This exploratory and descriptive study followed a cross-sectional and qualitative character. The sample consisted of 18 Brazilian women self-reported as lesbians, ranging from 19 to 42 years (M = 26, SD = 6.1). A sociodemographic questionnaire and semi-structured interviews were used to collect the data. The data were analyzed through thematic categorical analysis. The supposed existing methods were shown to not be specific, or target the prevention of STIs among women, since most of these means of prevention would be adaptations of existing methods or of items that would originally be used for other purposes. We conclude that elements of programmatic order seem to affect more intensively for a situation of greater vulnerability to lesbian health, and these are also related to individual and social elements.

Resumen El presente estudio tuvo como objetivo general analizar la vulnerabilidad en la salud sexual y las prácticas preventivas frente a las infecciones sexualmente transmisibles (IST) en las relaciones afectivo-sexuales de lesbianas. Se trató de un estudio exploratorio y descriptivo, de carácter transversal y cualitativo. La muestra fue compuesta por 18 participantes mujeres, brasileñas, que se autodefinen lesbianas, con edades entre 19 y 42 años (M = 26, DE = 6,1). Para la recopilación de los datos, se utilizó cuestionario sociodemográfico y entrevistas semiestructuradas. Los datos fueron analizados por medio del análisis categorial temático. Se evidenció que los supuestos métodos existentes no son propios, específicos o pensados para la prevención de las IST entre mujeres, teniendo en cuenta que la mayoría de ellos son adaptaciones de métodos ya existentes o adaptaciones de ítems que originalmente se utilizan con otros fines. Se concluye que los elementos programáticos pueden influir más en una situación de mayor vulnerabilidad a la salud de las lesbianas, aunque también se asocian a elementos individuales y sociales.

HPV infection and endometriosis: a systematic review and meta-analysis / Infecção por HPV e endometriose: uma revisão sistemática e meta-análise

Introduction: Recent research has focused on the role of persistent ascending bacterial infections and Sexually Transmitted Infections (STI) as an associated factor of endometriosis. Indeed, some studies investigated the possible role of HPV in endometriosis, but this topic remains inconclusive. Objective: The present study aims to meta-analyze research that assessed the presence of HPV infection in patients with endometriosis. Methods: MEDLINE, Embase, Scopus, LILACS, Cochrane Library, and OpenGrey were searched until February 10th, 2020. Search terms included "endometriosis" and "HPV" without language restrictions. Pooled relative risks and 95% confidence interval (95%CI) were calculated, and heterogeneity was assessed with I-squared (I2 ). Results: The meta-analysis with low heterogeneity found a twice as much relative risk in women exposed to HPV in relation to the unexposed control. Conclusion: The results indicate that HPV could be a risk factor for the development of endometriosis

Introdução: Pesquisas recentes enfocaram o papel das infecções bacterianas ascendentes persistentes e das infecções sexualmente transmissíveis (IST) como um fator associado à endometriose. De fato, alguns estudos investigaram o possível papel do HPV na endometriose, embora o tópico permaneça inconclusivo. Objetivo: O presente estudo tem como objetivo meta-analisar pesquisas que avaliaram a presença de infecção por HPV em pacientes com endometriose. Métodos: Foram realizadas buscas nas bases MEDLINE, Embase, Scopus, LILACS, Biblioteca Cochrane e OpenGrey até 10 de fevereiro de 2020. Os termos de pesquisa incluíram "endometriose" e "HPV" sem restrição de idioma. Riscos relativos agrupados e intervalo de confiança de 95% (IC 95%) foram calculados, e a heterogeneidade foi avaliada com I-quadrado (I2 ). Resultados: A meta-análise com baixa heterogeneidade encontrou um risco relativo duas vezes maior em mulheres expostas ao HPV em relação ao controle não exposto. Conclusão: Os resultados indicam que o HPV pode ser um fator de risco para o desenvolvimento de endometriose.

Change of left ventricular torsion function and systolic synchronization in children with hypertrophic cardiomyopathy / 上海交通大学学报（医学版）

Objective: To assess left ventricular torsion function and systolic synchronization in children with hypertrophic cardiomyopathy (HCM) by using two-dimensional speckle tracking echocardiography (2D-STI), so as to provide theoretical basis for early clinical evaluation of cardiac function in children. Methods: Twenty-nine children with HCM in Shanghai Children’s Hospital, Shanghai Jiao Tong University from October 2018 to March 2019 were divided into two groups according to whether having clinical symptoms, i.e., asymptomatic HCM group (n=17) and symptomatic HCM group (n=12). Thirty normal children were also enrolled in the normal control group. All subjects underwent echocardiography, and the torsion-and strain-related data of the whole and different myocardial segments in the cardiac sections of left ventricle were obtained by 2D-STI. Results: Left ventricular strain analysis showed that the left ventricular longitudinal strains of both HCM groups decreased significantly compared with the normal control group (P<0.05), while the radial and circumferential strains increased significantly (P<0.05). The maximum difference of peak time in different segments on six cardiac sections in the symptomatic HCM group was significantly higher than that in the normal control group (P=0.000), while the difference between the asymptomatic HCM group and the normal control group was not significant. Left ventricular torsion function analysis showed that the global peak twists of left ventricle and positive peaks of rotation velocity in both HCM groups were significantly higher compared with the normal control group (P<0.05), standardized times to peak were longer (P<0.05), and negative peaks of rotation velocity and the untwisting rates were lower (P<0.05). Conclusion: In the children with HCM, the left ventricular torsion function is enhanced and diastolic function is weakened. In the symptomatic children, the left ventricular systolic synchrony is poor.

Chemsex y uso de sustancias durante las relaciones sexuales: resultados de una encuesta realizada en Argentina / Chemsex and use of substances during sexual intercourse: results of a survey conducted in Argentina

Introducción: Chemsex está relacionado con el uso de ciertas drogas que facilitan la excitación y el prolongar la duración de los encuentros sexuales.Objetivo: Describir el perfil de consumo de los usuarios de sustancias durante las relaciones sexuales (SRS) y su relación con variables demográficas, de estilo de vida y de salud.Métodos: Estudio descriptivo y transversal realizado a través de una encuesta autoadministrada y anónima en el marco de la plataforma Google Forms® que se transmitió en diferentes redes sociales. Objetivo: describir los aspectos demográficos y de estilo de vida de los encuestados y del subgrupo de usuarios de SRS y chemsex.Resultados: Se recibieron 2924 encuestas; 421 personas (16,9%) refirieron haber consumido al menos una vez uno o más de los siguientes: mefedrona, metanfetamina, crystal meth, GHB/GBL, cocaína, LSD, poppers, ketamina y éxtasis. Chemsex se definió como el consumo de los tres primeros y su prevalencia fue del 1,1%. El perfil de usuario de SRS y chemsex en nuestro estudio fue un hombre de entre 26 y 35 años, HSH y habitante de la Ciudad de Buenos Aires. Hubo mayor proporción de personas con VIH y diagnósticos de ITS en el último año dentro de los usuarios de SRS y chemsex.Conclusiones: Esta es la primera encuesta que trata este tema en nuestro país y en América Latina. Teniendo en cuenta la tendencia a un menor uso de los condones RESUMENARTÍCULO ORIGINALISSN 2314-3193. Actualizaciones en sida e infectología. Buenos Aires. noviembre 2020. volumen 28. número 103: 40-50y a presentar más diagnósticos de ITS y VIH en la población de usuarios de SRS, consideramos de interés conocer la epidemiología en nuestra población

Introduction: Chemsex is related to the use of certain drugs to facilitate sustained arousal and induce a feeling of instant rapport with sexual partners.Aim: To describe the consumption profile of users of substances during sexual intercourse (SSI) and its relationship with demographic, lifestyle and health variables.Methods: Descriptive and cross-sectional study conducted through a self-administered and anonymous survey under the Google Forms platform ® which was broadcasted on different social networks. Main outcome measures: Description on demographic and lifestyle aspects of the respondents and in the subgroup of SSI and chemsex users.Results: 2924 surveys were received; 421 people (16.9%) referred to having consumed at least once one or more of the following: mephedrone, crystal meth, GHB/GBL, cocaine, LSD, poppers, ketamine and ecstasy. Chemsex was defined as the consumption of the first three and its prevalence was 1.1%. A SSI and chemsex user profile in our study was a man between 26 and 35 years, MSM and inhabitant of the city of Buenos Aires. SSI and chemsex users were more likely to and STI in the last year and to have HIV diagnosis.Conclusions: This is the first survey that deals with this issue in our country and in Latin America. Accounting for the tendency to less use of condoms and to present more diagnoses of STIs and HIV in the population of SSI users, we consider it necessary to study this subject in our country as the rising reports in world literature show a boost in substance use.Keywords: Chemsex, Drugs, HIV, VIH, STI, ITS.Chemsex and use of substances during sexual intercourse: results of a survey conducted in Argentina

Is early HIV infection diagnosis at a reference center a reality in the state of Ceara?

Abstract INTRODUCTION: Early diagnosis of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) can decrease transmission and significantly affect morbidity and mortality; however, Brazil still confronts the reality of late HIV diagnosis. METHODS: Medical records of 284 HIV-positive patients were reviewed in this cross-sectional study. RESULTS: Of all patients, 28% were diagnosed in the context of health assessments, whereas 27% were symptomatic at diagnosis. Early HIV infection (Group 1) was diagnosed in 60.2% of participants. They were younger than those with late diagnosis (Group 2) (p = 0.002). CONCLUSIONS: These findings highlight the need for strategies to increase HIV testing in asymptomatic individuals and older patients.

Fatores associados às infecções sexualmente transmissíveis: inquérito populacional no município de São Paulo, Brasil / Factors associated with sexually transmitted infections: a population based survey in the city of São Paulo, Brazil

Resumo Descrevemos a frequência de infecções sexualmente transmissíveis (IST), os fatores associados e as orientações recebidas dos profissionais de saúde entre homens e mulheres no município de São Paulo. Estudo de corte transversal, com inquérito populacional, com indivíduos de 15 a 64 anos residentes em São Paulo. De 4057 indivíduos que iniciaram a vida sexual, 6,3% relataram IST durante a vida, 4,3% das mulheres e 8,2% dos homens. As IST mostraram associação, entre os homens, com: idade > 34 anos, não uso de preservativo na primeira relação sexual; e entre as mulheres idade > 25 anos. Mostraram-se fatores de proteção, entre os homens: não ter tido relações sexuais com pessoa do mesmo sexo; e entre as mulheres: início sexual > 15 anos de idade e não ter tido parceria casual no último ano. Quanto às orientações, 72,1% e 64,7% das mulheres as receberam sobre a importância de realizar testes para HIV e sífilis, respectivamente, enquanto foram ofertadas para menos da metade dos homens (40,2% e 38,6%). A elevada proporção de antecedentes de IST entre a população do município e os resultados deste estudo possibilitaram a construção, implementação e avaliação de políticas públicas de saúde para o enfrentamento das IST incluindo o HIV, com diminuição de barreiras de acesso aos preservativos e criação de um app para prevenção.

Abstract We determined the prevalence of sexually transmitted infections (STIs), the factors associated with infection and types of counseling received by men and women from health professionals in the City of São Paulo. The investigation consisted of a cross-sectional study conducted with men and women aged between 15 and 64 years living in the City of São Paulo. Of 4,057 individuals who had engaged in sexual activity, 6.3% reported previous history of a STI: 4.3% of women and 8.2% of men. The factors associated with STI were being aged over 34 years and not using a condom during first sexual intercourse, among men, and being aged over 25 years among women. Protective factors included not having had sexual intercourse with someone from the same sex, among men, and having initiated sexual activity after the age of 15 years and not having a casual sex partner over the last 12 months, among women. Counseling about the importance of HIV and syphilis testing was received by 72.1% and 64.7% of women, respectively, while fewer than half of the men received this type of counseling (40.2% and 38.6 %, respectively). The prevalence of previous history of a STI was high among the population of the City of São Paulo. The findings of this study informed the development, implementation, and evaluation of STI policies, including those directed at HIV, leading to a reduction in the barriers that hinder access to and use of condoms and the creation of STI prevention app.

A study on knowledge and protective practices of STIs among patients attending tertiary care center at Bikaner, Rajasthan

The increased risk of the transmission of HIV is known to be associated with the presence of STIs and despite the presence of the National STI Control Program in India the number of people with STIs remains high. More than 1 million people acquire a STI every day. The true prevalence of STIs can never be known because of inadequate reporting due to secrecy and stigma associated with them and most of them are not even notifiable. Objectives: (1) To study socio-demographic factors of patient's attending STI clinic (2) To assess knowledge of patients about STI/HIV. (3) To assess protective practices of patients towards STIs. Material and Methods: This cross sectional was conducted in STI clinic, PBM hospital, Bikaner from Dec 2014- Jan 2016 using pre-tested and pre-structured questionnaire. The study variables were analyzed using Epi-Info7 software with application of Mean, Proportion and OR, Chi-square. Results: Out of 97 patients 83.5% knew about STIs. 79.4% reported having knowledge about symptoms of STIs and most common symptom reported was itching over genitals and discharge (85.5%). Statistically significant difference was present between male and female patient's knowledge about premarital sex as a factor for acquisition of STIs. 79.3% were using condoms to protect from STIs. The difference was statistically significant between knowledge and practice regarding condom use (χ2 = 6.544, df=1, p=0.01). Statistically significant difference was present between male and female patients practice regarding regular visit to STI clinic. Conclusion: Knowledge of patients regarding protective practices is not matching with their protective behavior.

Resistência de Neisseria gonorrhoeae a antimicrobianos na prática clínica: como está o Brasil? / Antimicrobials resistance of Neisseria gonorrhoeae in clinical practice: where Brazil stands?

Estima-se que um milhão de infecções sexualmente transmissíveis (IST) sejam adquiridas por dia no mundo, segundo a Organização Mundial da Saúde. Elas podem ser causadas por diversos micro-organismos pelo contato sexual. Embora tratáveis, as infecções, como a clamidiana, sífilis, tricomoníase e gonorreia, são responsáveis por 350 milhões de novos casos de IST anualmente no mundo. A gonorreia é a segunda IST bacteriana mais prevalente no planeta e tem chamado atenção nos últimos anos em decorrência da baixa eficácia em seu tratamento. O agente etiológico é a Neisseria gonorrhoeae. Na maioria das mulheres, a infecção por esse micro-organismo é assintomática, dificultando ainda mais seu diagnóstico e tratamento e, portanto, aumentando o risco de desenvolvimento de suas complicações associadas. Mesmo quando diagnosticada, essa infecção está sujeita a um alto índice de insucesso terapêutico que se deve, principalmente, à grande plasticidade genética da N. gonorrhoeae para aquisição de genes cromossômicos ou plasmidiais de resistência. O aumento da resistência desse micro-organismo a antimicrobianos comumente utilizados no tratamento, como penicilina, tetraciclina e ciprofloxacina, tem sido relatado em diversos países. No Brasil, poucos estudos estão disponíveis, mas em alguns estados já foram relatadas linhagens resistentes à ciprofloxacina. Dessa forma, deve-se ressaltar a importância de novos estudos que visem descrever o perfil da resistência da N. gonorrhoeae a antimicrobianos. Tais achados certamente nortearão a implementação de sistemas de vigilância epidemiológica no país visto que, até o momento, as infecções por N. gonorrhoeae sequer estão incluídas na lista nacional de doenças e agravos de notificação compulsória.(AU)

According to the World Health Organization, approximately one million sexually transmitted infections (STI) are acquired daily in the world. These infections can be caused by several microorganisms via contact. The treatable STI, such as chlamydia, syphilis, trichomoniasis and gonorrhea, account for 350 million new cases of STI each year worldwide. Gonorrhoea is caused by Neisseria gonorrhoeae and is the second most common bacterial STI in the world. It has drawn more attention in the last years due to the low efficacy in its treatment. Most women with this infection are asymptomatic, which makes its diagnosis and treatment troublesome increasing the risk for its associated complications. Even when diagnosed, this infection is subject to a high rate of therapeutic failure mainly due to the great genetic plasticity of N. gonorrhoeae for the acquisition of chromosomal or resistance plasmid enes. Increased resistance of this microorganism to antimicrobials commonly used in treatment such as penicillin, tetracycline and ciprofloxacin has been reported in several countries. In Brazil, few studies are available, but in some states strains resistant to ciprofloxacin were alreadyreported. The refore, it is important to highlight the importance of new studies aimed at describing the resistance profile of N. gonorrhoeae to antimicrobials in Brazil context. These findings will certainly guide the implementation of epidemiological surveillance systems in the country, since until now N. gonorrhoeae infections do not figure into the national list of compulsorily notifiable diseases.(AU)

Self-reported reproductive tract infection/ sexually transmitted infection and health care seeking behavior among the women living in a slum of Kolkata

Background: Sexually Transmitted Infection (STI) is a public health problem of significance in most parts of the world. It adversely affects reproductive health in both sexes but its impact on women‟s reproductive health is far devastating. Objectives: The study was conducted to know the prevalence of self-reported STI among the currently married women living in the slum area of Kolkata, the factors related with it and also to study their care seeking behavior following the infection. Materials and methods: This community based descriptive study was conducted by interviewing currently married women residing in a slum of Kolkata. Symptoms of STI and healthcare seeking behavior following the infection were enquired. Symptoms were grouped into complexes and presumptive diagnosis was made. Results: The prevalence of symptoms suggestive of STIs in the study population was found to be 47.8%.The most common symptoms reported by the sufferers were low backache (29.6%), burning micturition (25.2 %), and genital itching (23.5%). All symptoms were more common in the women living in the joint family, having one or more history of abortion. Symptoms of urinary tract infection was more in the age group of >30 years and those with >10 years of marriage. Whereas, vaginitis was more common in <30 years (p= 0.01). Only 49.0% of the sufferers consulted a health facility for Chakrabarti S, Chakrabarti A. Self-reported reproductive tract infection/ sexually transmitted infection and health care seeking behavior among the women living in a slum of Kolkata. IAIM, 2017; 4(4): 46-52. Page 47 treatment and most of them (62.9%) availed health service from the urban health training centre of the area. Conclusion: The present study found high prevalence of self-perceived reproductive morbidity among women in the slum setting. In the study there was no scope of laboratory investigation and was based on recall of the event in preceding three months