ABSTRACT
Objective: To study the chemical constituents from Sabia parviflora. Methods: Various column chromatographic techniques were used to separate and purify the chemical constituents which structures were elucidated by spectral analysis. Results: Fifteen compounds were isolated and identified as 1,3,5-trimethoxybenzene (1), vanillic aldehyde 4-O-β-D-glucopyranoside (2), 2,6-dimethoxy-4-hydroxybenzyl alcohol 1-O-β-D-glucopyranoside (3), rel-5-(3S,8S-dihydroxy-1R,5S-dimethyl-7-oxa-6-oxobicyclo [3,2,1]-oct-8-yl)-3-methyl-2Z,4E-penta-dienoic acid (4), protocatechuic acid (5), 4-quinolinone-2-caboxylic acid (6), 3,4,5-trimethoxy benzoic acid (7), pyrocatechol (8), syringic acid-4-O-β-D-glucopyranoside (9), (-)-(7α,8S)-erythro-1-C-syringylglycerol 4-O-β-D- glucopyranoside (10), 3,4,5-trimethoxy benzoic acid (11), 1,2,4-trihydroxybenzene (12), ferulic acid (13), vanillic acid (14), and p-hydroxybenzoic acid (15). Conclusion: Compounds 1-11 are isolated from the genus of Sabia for the first time, and compounds 12-15 are isolated from this plant for the first time.
ABSTRACT
Objective To study the chemical constituents from the Sabia parviflora. Methods Various column chromatographic techniques were used to separate and purify the chemical constituents which structures were elucidated by spectral analysis. Results Fifteen compounds were isolated and identified as bis (2-ethylhexyl) benzene-1,2-dicarboxylate (1), dibutyl phthalate (2), darutigenol (3), sucrose (4), 3,5-dimethoxy-4-hydroxybenzaldehyde (5), vanillin (6), cleomiscosin C (7), grossamide (8), (-)-lyoniresino (9), ervatamisin (10), (+)-syringaresinol (11), seslignanoccidentaliol A (12), (+)-syringaresinol-4-O-β-D-glucopyranoside (13), (-)-simulanol (14), and (-)-7R,8S-dehydrodiconiferyl alcohol (15). Conclusion All the compounds are isolated from the genus of Sabia for the first time.
ABSTRACT
Objective: To investigate the chemical constituents from the stems and leaves of Sabia parviflora. Methods: Column chromatographies over silica gel, Sephadex LH-20, reverse phase C18, MCI, and semi-preparative HPLC were used repeatedly for separation and purification of chemical constituents, and their structures were identified by NMR and MS spectra data with those reported in literature. Results: Fourteen compounds were obtained from the petroleum ether extract of S. parviflora, and identified as β-sitosterol (1), mominine (2), (20S)-3-oxo-20-hydroxytaraxastane (3), fluoren-9-one (4), N-formyldehydroanonain (5), betulinic acid (6), dehydroformouregine (7), palmitic acid (8), 20-hydroxy-lupan-3-one (9), 3-oxooleanolic acid (10), erythrodiol (11), methyl betulinate (12), N-formyl-annonain (Z) (13), and N-formyl-O-methylisopiline (14). Conclusion: Among the 14 compounds, there are seven pentacyclic triterpenes, four alkaloids, and three other compounds; compounds 3-10 and 12-14 are isolated from this plant and the plants of Sabia Colebr. for the first time, and the 13C-NMR spectral assignments of compounds 5, 7, and 14 are reported for the first time.