ABSTRACT
Objective: To evaluate the relationship between dental caries and levels of salivary albumin in unstimulated saliva of adults between the age group of 18 and 40 years from Chennai with varying caries experience as determined by their Decayed Missing Filled Teeth (DMFT) scores. Material and Methods: The study was conducted on 60 healthy adult subjects with age group between 18 and 40 years. The healthy subjects without any chronic diseases, gingival or periodontal problems were selected. The patients were divided into four groups according to DMFT status as Group 1, DMFT 0; Group2, DMFT 1 5; Group 3, DMFT 6 10; and Group 4, as DMFT above 10. Unstimulated saliva samples were collected from each subjects and the salivary albumin levels were estimated using the bromocresol green method (albumin colorimetric test). The obtained data was statistically analysed using one way ANOVA and Tukey`s Honestly Significant Difference test. Results: The mean salivary albumin levels for the groups 1, 2, 3 and 4 were .086 ± .009 mg/ ml, .083 ±.006 mg/ml, .070 ± .008 mg/ml and .056 ±.009 mg/ml respectively. There was an increase in incidence of caries with decrease in salivary albumin level. There was a statistically significant difference among the groups except group 1 and 2. Conclusion: There is a significant relationship between the salivary albumin level and the incidence of dental caries. An increase in incidence of caries with decrease in salivary albumin levels was seen suggestive of its importance in maintenance of tooth integrity. (AU)
Objetivo: Avaliar a relação entre cárie dentária e níveis de albumina salivar na saliva não estimulada de adultos entre a faixa etária de 18 e 40 anos da população de Chennai com experiência de cárie variável, conforme determinado pelos escores do índice de dentes cariados, perdidos e obturados (CPOD). Material e Métodos: O estudo foi realizado em 60 indivíduos adultos saudáveis com faixa etária entre 18 e 40 anos. Os indivíduos saudáveis sem doenças crônicas, problemas gengivais ou periodontais foram selecionados. Os pacientes foram divididos em quatro grupos de acordo com o status CPOD como Grupo 1, CPOD 0; Grupo 2, CPOD 1 5; Grupo 3, CPOD 6 10; e Grupo 4, como CPOD acima de 10. Amostras de saliva não estimuladas foram coletadas de cada indivíduo e os níveis de albumina salivar foram estimados usando o método de bromocresol verde (teste colorimétrico da albumina). Os dados obtidos foram analisados estatisticamente usando one way ANOVA e teste de Tukey. Resultados: Os níveis médios de albumina salivar para os grupos 1, 2, 3 e 4 foram de 0,086 ± 0,009 mg / ml, 0,083 ± 0,006 mg / ml, 0,070 ± 0,008 mg / ml e 0,056 ± 0,009. mg / ml, respectivamente. Houve aumento na incidência de cárie com diminuição do nível de albumina salivar. Houve diferença estatisticamente significante entre os grupos exceto grupo 1 e 2. Conclusão: Existe uma relação significativa entre o nível de albumina salivar e a incidência de cárie dentária. Um aumento na incidência de cáries com diminuição nos níveis de albumina salivar foi visto como sugestivo de sua importância na manutenção da integridade dentária.(AU)
Subject(s)
Dental Caries , AlbuminsABSTRACT
Aim: To analyze the relationship between dental caries, albumin in young adults between the age group of 20 to 30 years from South Canara district, Karnataka with varying caries experience as determined by their caries progression Methods and Materials: Eighty subjects from the outpatient department ranging between 20 to 30 years of age were screened and evaluated for their caries experience. Based on their level of caries a total of 80 subjects were selected and divided into four groups of 20 subjects each as follows; Group 1: enamel caries, Group 2: dentinal caries, Group 3: pulpal caries, Group 4: control group. The saliva was collected and analyzed for the presence of albumin levels in saliva and correlated to the same levels in serum. The statistical analysis was done using one way ANOVA test. Results: According to the present study there is an increase in the levels of caries with decrease in the levels of albumin. Serum albumin levels were also found to be decreased in caries prone individuals, hence showing a significant correlation between serum and salivary albumin levels. Conclusions: In the present study we found an inverse relationship between the levels of albumin in saliva and dental caries confirming the importance of albumin levels in inhibiting caries progression. Besides a correlation was also found between the levels of albumin in saliva and serum. Hence it can be used as a biochemical indicator in evaluating the susceptibility of caries.
ABSTRACT
The saliva circulating in the mouth at any given time is termed as whole saliva and it comprises of a mixture of secretions from the major and minor salivary glands and traces from the gingival crevicular fluid. It serves as a mirror of the body’s health as it contains proteins, hormones, antibodies and other molecules that are frequently measured in standard blood tests to monitor health and disease. Purpose:- In the present study we evaluated and analysed the interdependent or non-interdependent alterations of physical properties like ph, flow rate, buffering cpapcity and biochemical properties like salivary total protein,albumin,sIgA,and calcium in periodontal disease in different age groups and thereby assessed the significance and role of various salivary parameters as a diagnostic aid in the detection of alterations in oral tissue integrity. Materials and Metthods: - 60 cases and controls were taken for the study and three physical and four biochemical parameters were evaluated in all of them for each age group of 7 to 18 yrs., 18 to 36 yrs. and 40 to 60 yrs. Ttest and Pearson test were used to analyze the data. Results:-Periodontitis patients showed significant change in salivary albumin and some change in buffer capacity with significant intergroup alterations of pH and calcium levels.Certain parametric changes were correlative also. Conclusion:- Changes in physical and some biochemical properties like calcium and sIgA in periodontitis cases were interrelated and an indirect effect of periodontitis. However, changes in albumin and therefore total proteins were to a greater extent a direct effect of periodontal inflammation.