ABSTRACT
Sarcomatous carcinoma of the gallbladder is a very rare disease. There are few case reports worldwide. We experienced a case of sarcomatous carcinoma of the gallbladder. This 45-year-old male patient complained abrupt and continuos right upper quadrant pain for 4 hours. He was diagnosed as acute calculous cholecystits on abdominal sonography. He received laparoscopic cholecystectomy after conservative treatment for 3 days. During the operation the wall of gallbladder was so hard, thickened that cancer was suspected and the frozen biopsy proved osteogenic sarcomatous carcinoma. So, operation was converted to open laparotomy and a right hepatic lobectomy and choledochus resection with regional lymph node dissection was done. On 25th day of surgery, ascitic fluid collection was noticed on abdomen and multiple hematogenous metastasis on remnant liver was found on abdominal CT scan. The patient expired on 48th day of surgery due to cancer cachexia.