ABSTRACT
Sclerosing stromal tumor is a rare ovarian tumor, occurring in young adults in the second and third decade of life. We report clinical and histopathological features of three cases of sclerosing stromal tumor of the ovary with a review of literature. The tumor has distinct histological features and is easily recognizable when a high index of suspicion is maintained in young patients presenting with an ovarian mass. These tumors are benign and can be treated successfully by enucleation or unilateral ovariotomy.
Subject(s)
Female , Humans , Young Adult , Ovarian Neoplasms , OvaryABSTRACT
A sclerosing stromal tumor of the ovary (SST) is an extremely rare benign solid ovarian tumor,which is derived from the ovarian stroma and is a distinct subtype of sex cord-stromal tumor.It can not just be diagnosed accurately by routine preoperative physic-chemical examinations and postoperative immunohistochemical examinations.Recently,the application of fine needle aspiration cytology (FNAC) has improved diagnostic accuracy,but the final diagnosis relies on pathological examination.Compared with the traditional way of oophorectomy and salpingo-oophorectomy,the laparoscopic removal of SST will improve future success of pregancy.Besides,SST is an obvious endemic problem.Therefore,an increase in preoperative diagnosis rate of SST can avoid casual extension of resection during surgery and protect patients' fertility.
ABSTRACT
Sclerosing stromal tumor (SST) of the ovary is a rare, benign tumor. The most common clinical symptom is menstrual irregularity. Diagnosis of SST is often made by postoperative pathologic examination. The important differential diagnoses are other sex cord stromal tumors including fibroma, thecoma and etc. We present four cases of SST of the ovary during 10 years with a brief review of the literature.
Subject(s)
Female , Diagnosis, Differential , Fibroma , Ovary , Sex Cord-Gonadal Stromal Tumors , ThecomaABSTRACT
Sclerosing stromal tumor (SST) is an uncommon benign tumor of the ovary, representing 2~6% of all stromal ovarian tumors. It is a distinct benign neoplasm that differs from fibromas, thecomas, luteinized tumors and steroid cell tumors. It presents most often with non-specific symptoms and tumor markers usually remain normal. However massive ascites is a rare symptom. We report a case of sclerosing stromal tumor with massive ascites and elevated CA 125 with brief review of literature.
Subject(s)
Female , Ascites , Fibroma , Lutein , Ovary , Thecoma , Biomarkers, TumorABSTRACT
Sclerosing stromal tumor (SST) is an uncommon benign tumor of the ovary, representing 2~6% of all stromal ovarian tumors. It is a distinct benign neoplasm that differs from fibromas, thecomas, luteinized tumors and steroid cell tumors. It presents most often with non-specific symptoms and tumor markers usually remain normal. However massive ascites is a rare symptom. We report a case of sclerosing stromal tumor with massive ascites and elevated CA 125 with brief review of literature.
Subject(s)
Female , Ascites , Fibroma , Lutein , Ovary , Thecoma , Biomarkers, TumorABSTRACT
Sclerosing stromal tumor (SST) is a rare benign neoplasm of ovarian stromal origin and predominantly affects young women in the second and third decades. This tumor characteristically differentiates itself histologically and clinically from both thecomas and fibromas. We present a case of huge SST of the ovary weighing 10 kg in a 71-year-old postmenopausal woman with a brief review of the literature.
Subject(s)
Aged , Female , Humans , Fibroma , Ovary , ThecomaABSTRACT
Sclerosing stromal tumor (SST) is a rare benign neoplasm of ovarian stromal origin and predominantly affects young women in the second and third decades. This tumor characteristically differentiates itself histologically and clinically from both thecomas and fibromas. We present a case of huge SST of the ovary weighing 10 kg in a 71-year-old postmenopausal woman with a brief review of the literature.
Subject(s)
Aged , Female , Humans , Fibroma , Ovary , ThecomaABSTRACT
Nevoid basal cell carcinoma syndrome is inherited as an autosomal dominant trait with variable expressivity. This is characterized by multiple basal cell carcinomas, skeletal abnormalities, ectopic calcification, palmoplantar pits, central nervous system abnormalities, and multiple odontogenic keratocysts of the jaw. We report a case of nevoid basal cell carcinoma syndrome occurring in 14 year old girl, she had multiple basal cell carcinomas, spina bifida in the cervical vertebrae, forked ribs, hypertelorism, ectopic calcification of falx cerebri, palmoplantar pits, medulloblastoma, meningioma and sclerosing stromal tumor of the ovary. Her father had the same clinical features.
Subject(s)
Adolescent , Female , Humans , Basal Cell Nevus Syndrome , Carcinoma, Basal Cell , Central Nervous System , Cervical Vertebrae , Fathers , Hypertelorism , Jaw , Medulloblastoma , Meningioma , Odontogenic Cysts , Ovary , Ribs , Spinal DysraphismABSTRACT
Sclerosing stromal tumor is a rare benign neoplasm of ovarian stromal origin, distinct from the thecoma-fibroma group and steroid (lipid) cell tumors clinically, pathologically, and radiographically. Unlike the thecoma-fibroma group of ovarian stromal tumors, which tend to occur in the fifth and sixth decades, the sclerosing stromal tumor predominantly affects young women with a mean age of 28 years. Microscopic examination reveals a heterogenous picture that is characterized by sclerosis, prominant vascularity and a disorganized admixture of fibroblasts and vacuolated cells. We could not demonstrate unequivocal hormonal activity in this case, although suggestive evidence for it has been reported in the literature in the form of clinical, histologic, electron microscopic and immunohistochemical findings. We recently experienced a case of sclerosing stromal tumor of the ovary in 20 year-old virgin woman. We report a case here with a brief review of the literature.
Subject(s)
Female , Humans , Young Adult , Fibroblasts , Ovary , SclerosisABSTRACT
Sclerosing stromal tumor (SST) is a rare benign ovarian neoplasm and predominantly affects young women in the second and third decades with distinctive clinical features like irregular mensturation and dysmenorrhea. SST is usually solid and the possibility of malignancy should be considered. Recently some authors reported it is possible to predict the presence of this tumor preoperatively on the basis of the contrast enhanced magnetic resonance imaging (MRI) findings. We experienced a case of sclerosing stromal tumor of the ovary with characteristic clinical, pathologic and radiologic findings. We report this case with a brief review of the literature.
Subject(s)
Female , Humans , Dysmenorrhea , Magnetic Resonance Imaging , Ovarian Neoplasms , OvaryABSTRACT
Sclerosing stromal tumor of ovary is extremely rare benign neoplasm, occurring predominently in the second and third decades of life. It was first described by Chalvardjian and Scully in 1973 and by Damjanov in 1975 as distinctive subtype of other ovarian sex cord stromal tumor. This tumor differs from the fibroma, thecoma and lipid cell tumor clinically and pathologically by showing pseudolobular pattern, prominent vascularity and cell heterogeneity. We report a case of sclerosing stromal tumor of the ovary in 30-year-old woman with brief review of the literature.
Subject(s)
Adult , Female , Humans , Fibroma , Ovary , Population Characteristics , Sex Cord-Gonadal Stromal Tumors , ThecomaABSTRACT
Sclerosing stromal tumor, which was first described by Chalvardjian and Scully in 1973, is a very rare benign tumor of the ovary. This tumor differs from the fibroma, thecoma and lipoid cell tumor clinically and pathologically by showing prominent pseudolobular pattern and hypervascularity. We experienced a case of sclerosing stromal tumor of the ovary in 38 year-old woman. We report this case with a brief review of the literature.