ABSTRACT
Objective: To study the chemical constituents of the stems and leaves of mangrove plant, Scyphiphora hydrophyllacea. Methods: The chemical constituents of S. hydrophyllacea were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literatures. Results: A total of 18 compounds were isolated from the 90% ethanol extract of the stems and leaves of S. hydrophyllacea, which were identified as pomonic acid (1), euscaphic acid (2), dammaradienyl acetate (3), erythrodiol (4), lupenyl acetate (5), 30-oxo-lupeol (6), maslinic acid (7), 23-hydroxyursolic acid (8), β-amyrenone (9), acacetin (10), chrysoeriol (11), jaceosidin (12), kumatakenin (13), isosakuranetin (14), taxifolin (15), lyoniresinol (16), medioresinol (17), and balanophonin (18). Compounds 1-9 were triterpenoids, compounds 10-15 were flavonoids and compounds 16-18 were lignans. Conclusion: All compounds are isolated from the genus Scyphiphora for the first time.