ABSTRACT
No abstract available.
ABSTRACT
Oncocytic lipoadenoma is a rare tumor, with only 18 cases having been reported since the first in 1998. We encountered a case of oncocytic lipoadenoma presenting as a slowly growing parotid mass in a 71-year-old man. This tumor is characteristically comprised of a mixture of oncocytes and adipocytes. The present case is one of five reported cases of oncocytic lipoadenoma showing sebaceous differentiation. The results of immunohistochemical study with DOG1 antibody supported the origination of this tumor in the striated duct.
Subject(s)
Aged , Humans , Adipocytes , Oxyphil Cells , Parotid GlandABSTRACT
Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprised of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual for more than four tumors to arise simultaneously within a single sebaceus nevus. Here in, we report a case of a 70-year-old woman with six neoplastic proliferations including a syringocystadenoma papilliferum, pigmented trichoblastoma, tubular apocrine adenoma, sebaceoma, tumors of follicular infundibulum and superficial epithelioma with sebaceus differentiation arising in a long standing nevus sebaceus on the scalp. Our case is extraordinary because a single nevus sebaceus contained six neoplastic proliferations with differentiation toward the folliculosebaceous-apocrine unit.
Subject(s)
Aged , Female , Humans , Adenoma , Carcinoma , Hamartoma , Nevus , Nevus, Sebaceous of Jadassohn , Scalp , SkinABSTRACT
Tumor of the follicular infundibulum (TFI) is an uncommon benign adnexal tumor that usually presents as a solitary keratotic papule on the face or scalp of elderly patients. Histopathologically, it typically manifests as a plate-like fenestrated proliferation of monomorphic pale-staining cells. A 76-year-old male presented with about a 2 cm, well-defined, yellowish to brownish, slightly elevated, twisted and bent, interrupted, cord-like plaque on his left lower abdomen. Microscopic examination revealed a sharply demarcated plate-like proliferation of pale cells localized in the papillary dermis with multiple connections to the overlying epidermis. The histopathological features were compatible with TFI, except for foci of sebaceous differentiation. There has been one previous case report of TFI with sebaceous differentiation in the English medical literature. Herein, we report on a singular case of TFI with sebaceous differentiation.
Subject(s)
Aged , Humans , Male , Abdomen , Dermis , Epidermis , ScalpABSTRACT
Case Report: We report the case of an oncocytic sialolipoma of the submandibular gland with sebaceous differentiation in a 73-year-old man. The initial symptom was a right submandibular painless mass. Ultrasonography showed a hypoechoic oval mass posterior to the submandibular gland. The tumorectomy was performed with preservation of the salivary gland. The tumor was composed of mature adipose tissue surrounded by a thin fibrous capsule, multiple nodules of oncocytes, normal ductal-acinar units with focal ductal sebaceous differentiation. Discussion: We reviewed literature of the reported cases of mixed tumors of the salivary glands composed of mature adipose tissue with oncocytosis, salivary ducts, and acini with sebaceous differentiation. Conclusions: Sialolipoma and lipoadenoma with or without oncocytosis and/or sebaceous differentiation should be considered organ-specific tumors with a distinct histological appearance and specific terminology.
ABSTRACT
Superficial epithelioma with sebaceous differentiation (SESD) is a rare benign neoplasm that shows unique histologic features despite of the non-specific clinical findings. It is histopathologically characterized by a superficial multilobular plate-like proliferation of basaloid cells with clusters of sebocytes, and the plate-like proliferation has numerous broad attachments to the overlying epidermis. We report here on a case of multiple SESDs that presented on the trunk and extremities of 59-year-old woman.
Subject(s)
Female , Humans , Middle Aged , Carcinoma , Epidermis , ExtremitiesABSTRACT
Superficial epithelioma with sebaceous differentiation (SESD) is a histologically distinct, rare, benign neoplasm characterized by a superficial plate-like proliferation of basaloid cells with broad attachments to the overlying epidermis. Clusters of sebaceous cells were present within the lobules. We herein report a case of SESD in a 73-year-old female.
Subject(s)
Aged , Female , Humans , Carcinoma , EpidermisABSTRACT
Superficial epithelioma with sebaceous differentiation (SESD) is a rare benign neoplasm with peculiar histopathologic characteristics. It is characterized by a superficial plate-like proliferation of basaloid to squamoid cells with broad attachments to the overlying epidermis. Keratin-filled cysts and clusters of sebaceous cells are present within the lobules. We herein report an additional case of SESD which developed on a 68-year-old female.
Subject(s)
Aged , Female , Humans , Carcinoma , EpidermisABSTRACT
Antecedentes: Los tumores benignos de la piel se definen como el crecimiento autónomo de tejido sin relación con el patrón normal de crecimiento tisular, que persiste después del estímulo que le dio origen. Prácticamente todos los humanos presentan algún tumor benigno, pero la mayoría de las veces no se busca atención ya que no producen molestias. Son escasos los registros sobre la frecuencia de los tumores benignos. El objetivo de este estudio fue informar el número de tumores benignos en el Departamento de Dermatología de nuestro hospital. Material y métodos: Se realizó un estudio retrospectivo en el que se revisaron los registros de histopatología del periodo 2000 a 2006. Se registró año, número de biopsia, sexo, edad, topografía, diagnóstico clínico y diagnóstico histológico. Resultados: Se analizaron 9436 registros de biopsias, de las cuales 3765 fueron tumores benignos, de éstos se eliminaron 595 biopsias por falta de datos, para un total de 3170. Los tumores más frecuentes por grupo histopatológico en forma descendente fueron los tumores melanocíticos, quistes, tumores fibrosos, vasculares, de la epidermis, de tejido adiposo, del pelo, neurales, glandulares, sebáceos, de cartílago y hueso, y de músculo liso. Los tumores más frecuentes en general fueron nevos melanocíticos, quistes epidermoides, queratosis seborreicas, granulomas piógenos, lipomas y dermatofibromas. Conclusiones: Los tumores benignos más frecuentes fueron los melanocíticos constituidos por nevos de unión, intradérmicos y compuestos, y los quistes epidermoides. Esta serie proporciona información de los tumores benignos más comunes en un servicio dermatológico.
BACKGROUND: Benign skin neoplasms are defined as autonomous growing tissue unrelated to normal growing of the skin, that persist even after the originating stimulus dissapears. Almost all human beings have a certain number of benign cutaneous neoplasms and many never seek medical attention. There is a dearth of information regarding the frequency of these tumors. The aim of this study was to record the number of benign tumors studied at the Dermatology Department of a medical facility. MATERIAL AND METHODS: A retrospective study analyzed medical records between 2000 and 2006. We included year of admission, number of biopsies, sex, age, tumor location, histological and clinical diagnoses. RESULTS: We analyzed 9,436 biopsies of which 3,765 constituted benign neoplasms; 595 were not included and our total sample was 3,170 tumors. The most frequent tumors according to histopathological diagnoses in descending order were: melanocytic, cutaneous cysts, fibrous tumors, vascular tumors, epidermal tumors, fat tumors, tumors with hair differentiation, neural tumors, glandular tumors, tumors with sebaceous differentiation, cartilage and bone tumors, and smooth muscle tumors. The most common benign tumors were: Melanocytic nevi, epidermal cysts, seborrheic keratoses, pyogenic granulomas, lipomas and dermatofibromas. CONCLUSIONS: Melanocytes represented by melanocytic nevi (junctional, intradermic and compound) were the most frequent benign neoplasms, followed by epidermoid cysts. Our results illustrate the most common benign tumors observed in a dermatology department.
Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged, 80 and over , Neoplasms/epidemiology , Hospitals, General , Neoplasms/pathology , Retrospective StudiesABSTRACT
Superficial epithelioma with sebaceous differentiation is a rare-benign neoplasm, which is characterized by a superficial plate-like proliferation of basaloid to squamoid cells with broad attachments to the overlying epidermis. Herein, we describe a male patient with superficial epithelioma with sebaceous differentiation.
Subject(s)
Humans , Male , Carcinoma , EpidermisABSTRACT
A poroma has been thought to be derived from the peripheral cells of the eccrine duct. Nevertheless, there are some cases with sebaceous, follicular and apocrine differentiation, suggesting a possible apocrine origin. Herein, we report a 62-year-old man presented with a nodule surrounded by brownish plaque with hyperpigmented margin on the buttock for several months. Histopathologic examination revealed cords and broad columns of uniform poroid cells with sebaceous differentiation and melanin pigment.
Subject(s)
Humans , Middle Aged , Buttocks , Melanins , Pigmentation , PoromaABSTRACT
A poroma is usually described as a benign neoplasm arising from ductal epithelium of eccrine gland. However, in recent years there have been several reports on poromas featuring with combined sebaceous, follicular, and ductal differentiation, and thus establishment of this separate disease entity, "apocrine poroma" may well be justified considering the common embryologic origin of folliculosebaceous-apocrine unit. In our case, the tumor presented as a dark red nodule on the pubic area, being revealed as poroid neoplasm with folliculosebaceous components embedded in the lobules. Immunohistochemically, poroid cells stained with lysozyme. Taking the immunohistochemical staining results as well as the histopathologic findings of folliculosebaceous differentiation into consideration, we have concluded that this tumor is a case of an "apocrine poroma".
Subject(s)
Eccrine Glands , Epithelium , Muramidase , PoromaABSTRACT
Superficial epithelioma with sebaceous differentiation (SESD) is a rare benign neoplasm with peculiar histopathologic characteristics, which occurs in aged skin. We report upon a case of SESD occurring on the left upper back, which histopathologically is a superficial, multilobular tumor with numerous basaloid cells mixed with sebaceous cells attached to the overlying epidermis. This case represents a solitary benign neoplasm without any associated malignancy.
Subject(s)
Female , Humans , Middle Aged , Carcinoma, Basal Cell/pathology , Sebaceous Gland Neoplasms/pathology , Sebaceous Glands/pathology , Skin Neoplasms/pathologyABSTRACT
We report a 40-year-old woman with trichoblastoma on vertex scalp showing trichoepithelioma-like feature in upper part and focal sebaceous differentiation. The co-presence of trichoblastoma and trichoepithelioma-like feature in a same tumor represented that the inclusive term trichoblastoma is better for trichogenic tumors composed of follicular germinative cells, and sebaceous differentiation meant the common embryonic origin of folliculo-sebaceous-apocrine unit.
Subject(s)
Adult , Female , Humans , ScalpABSTRACT
A 70-year old man presented with postprandial upper abdominal pain of two months duration, accompanied by indigestion, weight loss, and anorexia. There was no abnormality noted in the lab results. Abdominal CT showed a 3-cm round cystic mass in the tail of the pancreas. A distal pancreatectomy was done. The patient was discharged in 9 days. The cystic wall was composed of a keratinizing squamous epithelium surrounded by subepithelial, dense lymphoid tissue. Some clusters of the sebaceous gland were noted but there was no sweat gland or hair follicle. These findings were consistent with a lymphoepiethelial cyst with sebaceous differentiation. The patient was followed up for 12 months post operatively, and no recurrence was noted.
Subject(s)
Aged , Humans , Abdominal Pain , Anorexia , Dermoid Cyst , Dyspepsia , Epithelium , Hair Follicle , Lymphoid Tissue , Pancreas , Pancreatectomy , Pancreatic Neoplasms , Recurrence , Sebaceous Glands , Sweat Glands , Tomography, X-Ray Computed , Weight LossABSTRACT
A 70-year old man presented with postprandial upper abdominal pain of two months duration, accompanied by indigestion, weight loss, and anorexia. There was no abnormality noted in the lab results. Abdominal CT showed a 3-cm round cystic mass in the tail of the pancreas. A distal pancreatectomy was done. The patient was discharged in 9 days. The cystic wall was composed of a keratinizing squamous epithelium surrounded by subepithelial, dense lymphoid tissue. Some clusters of the sebaceous gland were noted but there was no sweat gland or hair follicle. These findings were consistent with a lymphoepiethelial cyst with sebaceous differentiation. The patient was followed up for 12 months post operatively, and no recurrence was noted.
Subject(s)
Aged , Humans , Abdominal Pain , Anorexia , Dermoid Cyst , Dyspepsia , Epithelium , Hair Follicle , Lymphoid Tissue , Pancreas , Pancreatectomy , Pancreatic Neoplasms , Recurrence , Sebaceous Glands , Sweat Glands , Tomography, X-Ray Computed , Weight LossABSTRACT
I report a case of inverted follicular keratosis in a 68-year-old woman who presented a solitary, asymptomatic, slightly brownish verrucous nodule on her nose, present for 3 years. The lesion was characterized histologically by focal hyperkeratosis, marked acanthosis, horn cysts, numerous squamous eddies and sebaceous differentiation of the basaloid cells in the epidermis.