A systematic review of brain imaging studies of semantic priming / Revisão sistemática de estudos de neuroimagem do priming semântico

The present systematic review aims to address the contribution of brain imaging studies to the investigation of semantic priming (SP). Only studies from 2001 to 2017 using lexical decision tasks with visual and auditory stimuli, were considered. The review resulted in 20 articles, which showed semantic priming effects (SPE) in several brain areas (frontal and temporal lobes, cingulate gyrus, supplementary motor areas, and parietal cortex). In this way, the identification of activation in these areas varied as a function of stimulus onset asynchrony (SOA). Data suggests both hemispheres are involved on SPE, with a more robust role of the left hemisphere. Specifically, a decreased activation on the left middle temporal gyrus was found to be related to automatic SPE. This same area seemed to be related to SPE at long SOAs, along with the left inferior frontal gyrus and the anterior cingulated cortex. Therefore, a strong performance of the left hemisphere in semantic priming tasks could be observed, especially in the left middle temporal gyrus. Its activation was modulated by short and long intervals between stimuli, with more activation associated with longer intervals.

Associations between semantic priming and problem behavior in boy with attention deficit hyperactivity disorder / 中华行为医学与脑科学杂志

Objective To investigate the semantic priming of boy with attention deficit hyperactivity disorder( ADHD) and explore whether the semantic priming deficits was associated with behavioral problems by event-related potential(ERP). Methods Thirty boy with and without ADHD aged from 7 to 13 years were asked to finish the semantic Semantic judgment task. The study took advantage of t-test ( independent-samples) to compare the amplitude and latency of the N400 in both groups,as well as behavioral data.Behav-ioral problems were assessed by the Achenbach child behavior checklist( CBCL) ,and Pearson correlation a-nalysis were used to explore the relationship between behavioral problems and semantic priming. Result-s Under the condition of semantic correlation,the hyperactive factor of CBCL in ADHA group was positively correlated with ERP N400 amplitude ( r=0.44,P<0.05) and negatively correlated with reaction accuracy ( r=-0.48,P<0.05).Under the semantic irrelevant condition,the latency of ERP N400 in ADHA group was pos-itively correlated with hyperactivity factor (r=0.53,P<0.05)and aggression factor of CBCL(r=0.62,P<0.05).The N400 amplitude of the ADHD group was significant higher than that in the control group under se-mantic related conditions((-11.36±4.77)μV vs (-7.66±5.24)μV,P=0.006),and the latency of the N400 in ADHD was more delay((369.6±44.09)ms vs (341.27±24.54)ms,P=0.004),and the reaction times (RT) was much longer((936.18±135.03)ms vs (857.78±103.45)ms,P=0.014).The latency of the N400 in ADHD was more delay than that in the control group under semantic irrelevant conditions ( ( 383. 93 ±29.66)ms vs (362.33±29.66)ms,P=0.012),and accuracies of ADHD group was lower than that of control group(0.43±0.39 vs 0.81±0.23,P<0.01).Conclusion The present result indicates that children with ADHD exhibit a deficit in the semantic priming mechanism,and the deficit is positively correlated with hy-peractivity and impulsiveness.

Elaboração de lista de homônimos do Português Brasileiro para tarefas de processamento linguístico / Creation of a list of homonyms in Brazilian Portuguese for linguistic processing tasks

RESUMO Objetivo Apresentar procedimentos e etapas de elaboração de uma lista de homônimos, de seus significados e de imagens que os representam. Método Levantaram-se, por meio de pesquisa em livros escolares e dicionários, 103 homônimos do Português Brasileiro e seus significados. Os homônimos foram selecionados por critérios: serem substantivos; não eliciar mais que dois significados; representáveis por imagens. Selecionaram-se 26 homônimos e foram encontradas 2 imagens para cada significado. Para testar o instrumento participaram 20 crianças do 4º (N=10) e 5º anos (N=10) do Ensino Fundamental de escola particular do município de São Paulo. Para identificar os significados de maior e menor ocorrência, os escolares referiram o significado de cada palavra que lhes foi apresentada oralmente. Para verificar o reconhecimento das 52 imagens (uma imagem para cada um dos dois significados do homônimo), as 20 crianças foram instruídas a nomeá-las na apresentação em PowerPoint. As porcentagens de acertos foram calculadas. Resultados Dos 26 homônimos, dois foram excluídos, pois não houve nomeação para os significados. Duas imagens pouco reconhecidas foram substituídas por outras que melhor representaram os homônimos. Conclusão A lista de homônimos resultante apresenta 24 homônimos e 48 imagens (uma para o significado de maior e outra para o de menor ocorrência). A apresentação dos itens a escolares de 4o. e 5o. anos do EF indicou adequação da lista. O material mostrou-se reconhecível e apropriado para tarefas de priming semântico ou outras de processamento linguístico com homônimos em Português Brasileiro.

ABSTRACT Purpose This paper presents procedures and steps to create a list of homonyms, their meanings and representative images. Methods One hundred and three homonyms in Brazilian Portuguese were secluded through searches in text books and dictionaries and the meanings were verified. The homonyms were analyzed and selected according pre-established criteria. Twenty-six homonyms with two meanings were selected and one image was used to represent each meaning. To test the instrument, twenty elementary school children in 4th (n = 10) and 5ht (n = 10) grades were selected from a private school in São Paulo. To identify the meanings of major and minor occurrence, the students gave their understanding of the words presented to them orally. The students were also asked to name the fifty-two images to determine the degree of recognition. Percentages of accuracy were calculated. Results Among the 26 homonyms, two were excluded because the students were unable to name them. Two images were little recognized and, therefore, replaced with others that better represented the homonyms. Conclusion A list of 24 homonyms and 48 images (one for each meaning) was developed. The results of the presentation of these items to elementary school children in the 4th and 5th grades proved the adequacy of the list. The material is seen as efficient for use in recognition tasks and can be applied in semantic priming tasks.

Heterogeneity in semantic priming effect with a lexical decision task in patients after left hemisphere stroke / Heterogeneidade no efeito de priming semântico em pacientes após lesão cerebral do hemisfério esquerdo

ABSTRACT Investigations on the semantic priming effect (SPE) in patients after left hemisphere (LH) lesions have shown disparities that may be explained by the variability in performance found among patients. The aim of the present study was to verify the existence of subgroups of patients after LH stroke by searching for dissociations between performance on the lexical decision task based on the semantic priming paradigm and performance on direct memory, semantic association and language tasks. All 17 patients with LH lesions after stroke (ten non-fluent aphasics and seven non aphasics) were analyzed individually. Results indicated the presence of three groups of patients according to SPE: one exhibiting SPE at both stimulus onset asynchronies (SOAs), one with SPE only at long SOA, and another, larger group with no SPE.

RESUMO As investigações sobre o efeito de priming semântico (SPE) em pacientes após lesões cerebrais no hemisfério esquerdo (LH) têm mostrado divergências que podem ser explicadas pela variabilidade no desempenho encontrado entre os pacientes. O objetivo do presente estudo foi verificar a existência de subgrupos de pacientes pós-AVC no hemisfério esquerdo do cérebro, buscando associações e dissociações entre o desempenho na tarefa de decisão lexical no paradigma de priming semântico e o desempenho em tarefas diretas de memória, tarefas de associação semântica e de linguagem. Todos os 17 pacientes com lesão no LH após acidente vascular cerebral (dez afásicos não-fluentes e sete não afásicos) foram analisados individualmente. Os resultados indicaram a presença de três grupos de pacientes de acordo com o efeito de priming semântico. Um grupo de participantes que mostrou SPE em ambos os SOAs, um dos participantes com SPE apenas no SOA longo e um grande grupo sem SPE.

Processamento léxico-semântico explícito e priming semântico em lesão cerebral de hemisfério direito / Explicit lexical-semantic processing and semantic priming on right brain damage

É fundamental a melhor compreensão de alterações neuropsicológicas decorrentes de lesão de hemisfério cerebral direito (LHD). O objetivo deste estudo foi comparar os efeitos de priming semântico (EPS) e o desempenho em tarefas de processamento léxico-semântico explícito entre pacientes com LHD (n=11) e controles saudáveis (n=11). Investigaram-se também subgrupos de pacientes com LHD com relação a associações e dissociações entre o desempenho em tarefas de processamento léxicosemântico explícito (evocação lexical com critério semântico e julgamento semântico) e de priming semântico através de um estudo de série de casos. O priming semântico foi avaliado por uma tarefa de decisão lexical com estímulos monossêmicos com forte relação semântica e um Stimulus Onset Asynchrony de 500ms. Ambos os grupos apresentaram EPS e não diferiram significativamente nas tarefas de processamento léxico-semântico explícito. Contudo, no estudo de série de casos houve uma heterogeneidade no perfil de desempenho na amostra de pacientes em tarefas de processamento léxico-semântico explícito e de priming semântico. Os resultados indicam a importância de estudos de série de casos para o melhor entendimento de alterações no processamento léxico-semântico em LHD

It is essential a better understanding of neuropsychological deficits resulting from right hemisphere brain damage (RHD). This study aimed to compare semantic priming effects (SPE) and performance on explicit lexicalsemantic processing tasks between RHD patients (n=11) and healthy controls (n=11). It were also investigated subgroups of patients with RHD regarding associations and dissociations between performance on explicit lexical-semantic processing (lexical retrieval based on semantic criteria and semantic judgment) and semantic priming tasks through a case series investigation. Semantic priming was evaluated through a lexical decision task with monosemic stimuli with strong semantic relationship and 500ms Stimulus Onset Asynchrony. Both groups showed SPE and did not differ significantly on explicit lexicalsemantic processing tasks. However, there was heterogeneity in the performance of the patients sample on explicit lexical-semantic processing and priming tasks on the case series investigation. Results indicate the importance of case series investigations to a better understanding of deficits on lexical-semantc processing after RHD

Semantic priming effect after left hemisphere stroke / O efeito de priming semântico após AVC no hemisfério esquerdo

Semantic priming effect (SPE) refers to a facilitation in processing a target due to the semantic association between that and a preceding stimulus (prime). Recent neuroimaging researches supports the hypothesis that brain left hemisphere (LH) plays an important role on this phenomenon. The purpose of the present study was to compare the SPE between patients with LH brain lesions and their controls at two different stimulus onset asynchronies (SOA)s (300ms and 500ms). The sample was composed by 17 patients with LH lesion after stroke and 17 healthy controls matched on sex, age and educational level. They performed a lexical decision task on the semantic priming paradigm. Data showed no differences between groups. Clinical and control group didn`t present SPE at the 300ms SOA whilst both groups presented it at the 500ms SOA. Those findings cannot be understood as patient's impairments on SPE once control group performed similarly

O efeito de priming semântico se refere à facilitação no processamento de um estímulo alvo causada pela associação semântica existente entre este e um estímulo anterior (prime). Pesquisas recentes de neuroimagem corroboram a hipótese de que o hemisfério esquerdo tem um importante papel neste fenômeno. O objetivo do presente estudo foi comparar o efeito de priming semântico entre pacientes com lesão no hemisfério esquerdo e seus controles através de dois diferentes intervalos entre os estímulos (300ms e 500ms). A amostra foi composta por 17 pacientes com lesão no hemisfério esquerdo causada por acidente vascular cerebral e 17 controles pareados por sexo, idade e escolaridade. Os participantes realizaram uma tarefa de decisão lexical no paradigma do priming semântico. Os dados não mostraram entre os grupos. Nem o grupo clínico nem o controle apresentaram efeito de priming semântico com 300ms de intervalo entre os estímulos enquanto os dois grupos apresentaram no intervalo de 500ms. Esses achados não podem ser interpretados como déficit dos pacientes visto que os controles obtiveram um desempenho semelhante

Efeitos de priming semântico em tarefa de decisão lexical em crianças de 3ª série / Semantic priming effects during lexical decision task with 3rd grade children

No paradigma de priming semântico, mede-se a acurácia e velocidade de resposta ao estímulo-alvo, precedido por palavra semanticamente relacionada ou não relacionada (primes). Este trabalho apresenta um estudo pré-experimental de normas de associação semântica de palavras em 156 crianças e um estudo experimental, que avalia o efeito de priming semântico em 24 crianças em uma tarefa de decisão lexical. O experimento mostrou que as decisões lexicais para alvos reais foram significativamente mais lentas e menos precisas na condição prime não relacionado comparado à condição prime relacionado. Conclui-se que houve efeitos de priming semântico no reconhecimento visual de palavras em crianças, ou seja, o contexto semântico pré-ativou a representação da palavra alvo, facilitando a decisão lexical na condição de relação semântica.

In the semantic priming paradigm, accuracy and reaction time to a target-stimulus that is preceded by a prime (semantic related or unrelated to the target) are measured. This paper presents a pre-experimental study on word semantic association norms with 156 children and an experimental study that evaluated the effect of semantic priming in 24 children during a lexical decision task. Results showed that the lexical decisions for real targets were significantly slower and less accurate in the unrelated prime condition than in the related one. It means that there were semantic priming effects in children during visual recognition of words, that is, the semantic context pre-activated the target word representation, facilitating the lexical decision in the semantic related condition.

Avaliação do efeito de dica semântica e da indução de significado entre estímulos abstratos aquivalentes / Evaluation of semantic priming effect and induction of meaning among abstract equivalent stimuli

Relações semânticas entre estímulos equivalentes foram avaliadas utilizando "tentativas de decisão léxica" e diferencial semântico. Foram utilizadas as estruturas de treino conhecidas como "um-para-muitos" e "muitos-para-um" na geração de três classes de estímulos equivalentes envolvendo cinco conjuntos de estímulos: A, B, C, D e E. Para um grupo de participantes, denominado de Grupo Um para Muitos (GUM), as relações diretamente treinadas obedeciam à estrutura AB, BC, CD e CE; um outro grupo experimental, denominado de Grupo Muitos para Um (GMU), foi treinado na estrutura DC, EC, CB e BA. Para os dois grupos, os estímulos do conjunto B eram fotografias de faces expressando emoções e os estímulos dos conjuntos A, C, D e E eram figuras abstratas. A seguir, duas figuras (já vistas ou novas) eram apresentadas em seqüência, como "dica" e "alvo", em tentativas em que o participante respondia se reconhecia ou não a figura alvo. As respostas foram mais rápidas quando dica e alvo pertenciam à mesma classe, reproduzindo com estímulos abstratos equivalentes o efeito de dica semântica. Figuras abstratas foram então avaliadas por diferencial semântico. As avaliações do GUM foram similares às avaliações das faces por um grupo controle e as avaliações do GMU não foram. Os dados sugerem que a intensidade relativa da transferência de significados entre estímulos equivalentes pode depender da direção das relações que os participantes devem estabelecer.

Semantic relations among equivalent stimuli were evaluated by lexical decision tasks and a semantic differential. Two training structures, known as "one-to-many" and "many-to-one", were employed in order to generate three classes of equivalent stimuli involving five sets of stimuli: A, B, C, D and E. Stimuli for set B were pictures of faces expressing emotions whereas stimuli for sets A, C, D and E were abstract pictures. For one group of participants, the One-to-many Group, the directly trained relations were AB, BC, CD and CE; for the other experimental group, the Many-to-one Group, the directly trained relations were DC, EC, CB and BA. Two pictures were then presented in sequence as "prime" and "target" in trials in which participants responded whether they recognized or not the target. Responses were faster when prime and target belonged to the same equivalent class, reproducing the semantic priming effect. Abstract pictures were then evaluated through the semantic differential. Evaluations by the One-to-many Group were similar to the evaluations of the faces made by a control group, but those made by the Many-to-one Group were not. The data suggest that the transfer of meaning among equivalent stimuli may depend on the relations which are established by the participants.

Priming semântico em crianças: efeitos da força de associação semântica e frequência do alvo / Semantic priming in children: effects of prime-target association strength and target frequency

O priming semântico é um tipo de memória implícita que se caracteriza pelo efeito facilitador de um estímulo precedente no processamento de um estímulo posterior, causado pela relação semântica existente entre os dois. O objetivo deste estudo foi verificar relações entre os efeitos de priming semântico em crianças de 3ª série do Ensino Fundamental e as variáveis força de associação entre prime e alvo e frequência do alvo. Para isso, foram feitas correlações entre estas variáveis. Os resultados mostraram que quanto maior a frequência de ocorrência da palavra-alvo, mais rápidas e precisas eram as respostas das crianças na tarefa de decisão lexical. Além disso, verificou-se uma fraca correlação negativa entre a força de associação prime-alvo e as variáveis tempo de reação e precisão das respostas. Estes achados trazem implicações para a construção e interpretação de tarefas/experimentos de avaliação de funções cognitivas com estímulos linguísticos. Além disso, demonstram há necessidade de controlar e/ou manipular certas variáveis psicolinguísticas dos estímulos para aumentar a qualidade dos experimentos.

The semantic priming effect (SPE) can be understood as an improvement in performance derived from the context, in which a target processing is facilitated by the preceding stimulus (prime) because of a semantic association between them. This study aimed to verify if the association strength between prime and target and the frequency of the target is related to semantic priming effects found in third graders. For that, tests of correlations were done among these variables. Data demonstrated negative correlation between frequency of the target and variables reaction time and error percentage. Besides, it was also found a weak negative correlation between these variables and the association strength. These findings bring implications to the construction and interpretation of tasks and experiments that evaluate cognition with linguistic stimuli. Moreover, they demonstrate the need to control or manipulate some psycholinguistic variables of the stimuli in order to improve the quality of the experiments.

Study on auditory semantic priming effects in patients with aphasia / 中华行为医学与脑科学杂志

Objective To explore the characteristics of semantic priming effects in Chinese words with different association strength in patients with aphasia by auditory stimulation.Method Stimulus-response word pairs with different association strength including strong,moderate,weak,and no association categories were chosen from word association thesaurus as experiment materials.Both patients with aphasia(n=11)and normal subjects (n=16)were requested to finish an auditory lexical decision task for target words.Semantic priming effects were investigated by means of measuring reaction time(RT)and error rate of each word-pair.Results In patients with aphasia and normal subjects,the mean RTs were significantly shorter in strong,moderate and weak association strength words than in no association strength words(patients with aphasia(1270.20±47.70)ms,(1340.50±266.25)ms,(1429.70±317.07)ms vs(1549.00±325.87)ms,P＜0.05 and normal subjects(1140.2±274.48)ms,(1196.50±284.06)ms,(1262.10±274.31)ms vs(1391.20±315.68)ms,P＜0.05).In strong,moderate,and no association strength words,the mean RTs were no significant differences between two groups.In the weak association strength words,mean RTs were significantly longer in patients with aphasia than in normal subjects((1429.70±317.07)ms vs(1262.10±274.31)ms,P＜0.05).In two groups,mean error rates were significantly less in strong,moderate and weak association strength words than in no association strength words(patients with aphasia:7.73±6.07,4.55±7.23,6.82±8.15 vs 14.09±12.41,P＜0.05 and normal subjects:3.44±4.37,2.81±3.64,5.31±5.91 vs 10.94±11.14,P＜0.05).However,in strong association strength words,mean error rates were significantly higher in patients with aphasia than in normal subjects(7.73±6.07 vs 3.44±4.37,P＜0.05).In moderate,weak and no association strength words,there were no significant differences between two groups.Conclusion The patients with aphasia follow gradient of the association strength words like normal subjects and have semantic priming effects in the strong,moderate association strength words.

O paradigma de priming semântico na investigação do processamento de leitura de palavras / The semantic priming paradigm in the word reading processing investigation

O priming é um tipo de memória implícita (não declarativa) referente aos efeitos facilitadores de eventos antecedentes (primes) sobre o desempenho subseqüente (alvos). No priming semântico há uma relação de significado ou de contexto entre o prime e o alvo. Este paradigma pode ser utilizado como recurso metodológico para estudar, de forma indireta, o processamento semântico na leitura.Este artigo visa apresentar conceitos e discutir aspectos metodológicos do paradigma de primingsemântico e as possibilidades de uso para estudo do processamento da leitura. Será apresentada uma revisão do conceito e de procedimentos metodológicos do priming semântico nos estudos de leitura.Serão abordados os modelos teóricos de leitura de palavras (acesso ao léxico mental), os modelos explicativos para o efeito de priming semântico na leitura e serão analisadas pesquisas utilizando o paradigma para investigar o reconhecimento de palavras escritas. Conclui-se que, apesar dos estudos internacionais, especialmente os realizados com crianças, conduzirem a resultados não consensuais, o paradigma de priming semântico mostra-se útil para investigar o conhecimento semântico implícito eon-line, ou seja, durante o processamento das palavras lidas, o que torna sua testagem ecológica e menos artificial. As diferenças de resultados podem relacionar-se à variabilidade dos procedimentos metodológicos.

Priming is a type of implicit memory (non-declarative) referring to the facilitating effects of precedent events (primes) on subsequent performance (targets). In semantic priming there is a relation of signification or context between the prime and the target. This paradigm can be used as a methodological resource to study, in an indirect manner, the semantic processing in reading. This article aims to present concepts and discuss methodological aspects of the paradigm of semantic priming and the possibilities of using it in studying the process of reading. A revision of concepts andthe discussion of methodological aspects of the semantic priming paradigm in reading studies will bepresented. Theoretical models of word reading (access to mental lexicon), the explanatory models for the semantic priming effect in reading will be approached. And, studies using the paradigm to investigate the recognition of written words will be analyzed. Despite international studies that led tonon-consensual results, especially those undertaken with children, this study infers that the semantic priming paradigm shows to be useful in investigating implicit and on-line semantic knowledge, rather,during the process of reading words, which makes its testing more ecological and less artificial. The differences of results can be related to the variability of methodological procedures.

Study of Semantic Priming Effect in Patients with Brain Injury / 中国康复理论与实践

@# Objective To investigate the changes of the semantic priming effect in patients with brain injury.Methods Eight patients with Alzheimer's disease(AD),fifteen patients with vascular dementia(VD),seventeen patients with traumatic brain injury (TBI),twenty four healthy young subjects,and seventeen elderly healthy subjects as normal controls were estimated by Mini-Mental State Examination(MMSE),clinical memory scale,and process dissociation procedure(PDP) tasks.The data of all subjects were analyzed.Results The patients in the AD group had lower recollection and automatic scores than those in the young and elderly control groups in free association task(P<0.05～0.001).The recollection scores in the VD and TBI groups decreased significantly when compared with that in the young and elderly control groups in free association tasks(P<0.001),whereas the automatic scores had no significant difference among four groups(P>0.05).Conclusion AD patients exhibited impaired explicit memory and semantic priming effect,but retain normal perceptual priming effect;VD and TBI patients showed impaired explicit memory,but retained normal semantic priming effect.

Study of word naming reaction time of reading Chinese in patients with mild Alzheimer disease and mild cognitive impairment / 中国康复理论与实践

@#ObjectiveTo explore the pattern and the time course changes of semantic and phonological processing during Chinese language cognition study in patients with mild Alzheimer's disease(AD) and mild cognitive impairment (MCI).MethodsPatients with mild AD and MCI and normal controls matched with age, gender, level of education were enrolled in the single-character words naming task, which applied short and long stimulus onset asynchrony (SOA). Semantic, homophonic, semihomophonic and unrelated primes preceded the words as well as nonwords targets. Subjects were asked to read the targets aloud. Semantic and phonological priming effects were analyzed by comparing reaction time of semantic, homophonic or semihomophonic related targets to unrelated targets. The reaction time and accuracy for each response were recorded.ResultsThe mean reaction time of mild AD and MCI patients were prolonged for all types of priming in contrast with normal controls. Responses of the normal controls were faster during the long SOA comparing to short SOA, whereas the mild AD group's reaction time was longer for long SOA than for short SOA. Normal controls exhibited homophonic priming, whereas mild AD and MCI groups exhibited tonal inhibition effects.ConclusionThe speed of Chinese language cognitive processing decreased in mild AD and MCI patients. The phonological encoding and accessing ability may be impaired in mild AD and MCI.

Effects of Sleep Deprivation on Implicit Memory / 中国心理卫生杂志

Objective:To investigate the effects of sleep deprivation(SD)on implicit memory.Methods:32 young men were divided into four groups,SD21,SD45,SD69 and Control,8 men each group.Subjects were asked to finish the tests of word completion and words association.Results:After SD,both semantic priming and perceptual priming decreased significantly and the decrease were connected with the length of SD.In the same group,the decrease of perceptual priming of SD groups was significantly lowered than that of semantic priming.In perceptual priming,there was significantly different compared between groups except that of SD45 and SD69.In semantic priming,there was significantly different compared between groups except that of Control and SD21.Conclusions: SD has effect on implicit memory,and it's associated with the length of SD.After SD,there exits dissociation between semantic priming and perceptual priming.Perceptual priming is more affected.