A ten-year retrospective study on the survival outcomes among post-hysterectomy cervical cancer patients / Philippine Journal of Obstetrics and Gynecology

Background@#Cervical cancer is the most common gynecologic malignancy in the Philippines despite being a preventable disease. Radical hysterectomy with pelvic lymphadenectomy is considered the standard surgical treatment of choice for patients with cervical cancer confined to the cervix up to the upper vagina. However, recent studies show that a less radical approach can be offered to these patients with comparable outcomes to radical hysterectomy, but with lesser perioperative and post-operative morbidity.@*Objectives@#The purpose of this study was to compare the outcomes in terms of recurrence and survival among cervical cancer patients who underwent simple hysterectomy and radical hysterectomy seen in a tertiary government hospital.@* Methods@#The records of all cervical cancer patients who underwent radical hysterectomy and simple hysterectomy for the past ten years were reviewed.@*Results@#The incidence of cervical cancer patients who underwent simple hysterectomy from 2009-2018 is 0.37 per 100 person years or 0.592:16, lower than 1:16 ratio from 1964-1974, as reported by Manalo and Sotto.1 Only 9 out of 42 patients who underwent simple hysterectomy had cervical cancer screening within 1 year prior to surgery.@*Conclusion@#The most common indication for surgery was myoma uteri. Those who underwent radical hysterectomy had better recurrence free survival and overall survival than those who had simple hysterectomy.

Simple Advertent Hysterectomy in the Presence of Invasive Cervical Cancer / 대한산부인과학회잡지

To identify significant prognostic factors in patients undergoing simple hysterectomy in the presence of invasive cervical cancer, the records of 45 patients who had taken such a procedure between 1993 and 1997 were reviewed. Overall relapse-free survival and 5-year survival rates were 91.1 and 92.1%, respectively. Factors found to be significantly related to survival were the retrospectively determined stage(p=0.0000), the presence of residual disease(p=0.0001), and cell type(p=0.0000). By multivariate analysis, factor emerging as significantly detrimental to survival was the cell type. The presence of residual disease was a marginally significant factor(p=0.067). The expectations for survival of patients with residual tumor mass and/or with adenocarcinoma after simple hysterectomy appear to be markedly worse than those with others, so radical reoperation should be considered in those patients.

Radiotherapy of Invasive Cervical Cancer Following Simple Hysterectomy / 대한치료방사선과학회지

PURPOSE: Simple hysterectomy is not a standard surgery for invasive cervical carcinoma. This study was performed to investigate the efficacy of radiotherapy following simple hysterectomy in the invasive cervical cancer. MATERIALS AND METHODS: Retrospective analysis was done for 19 patients with invasive cervical carcinoma who were treated with radiotherapy following simple hysterectomy from April 1989 to December 1993. The median age of patients was 47 years old. Patients were treated with external beam radiation therapy alone (17) or external beam radiation therapy plus intra vaginal ovoid irradiation (2). The median follow up period was 46 months. RESULTS: The 4 year overall survival rate was 75%. The 4 year local control rate was 89%. Two patients had recurred at the locoregional and distant sites, and another two patients at distant sites. CONCLUSION: We confirmed that radiotherapy is the adequate treatment modality for patients with invasive cervical cancer who underwent simple hysterectomy.