Sinonasal Tumour- A Clinico-Pathological Study in a Tertiary Care Hospital

Introduction: Sinonasal tumours are relatively uncommontumours in the head-neck region. The aim of the present studywas to study the clinico-pathological profile of the sinonasaltumours and its management.Material and methods: It was a Prospective, observationalstudy. Forty Patients with sinonasal tumours, attending theotorhinolaryngology and Head-Neck surgery departmentof a tertiary-care hospital, Kolkata from October 2017 toSeptember 2018 were selected for the study. Previously treatedcases of sinonasal tumour with recurrence were excluded.They were evaluated by detailed history taking, properclinical examination, relevant radiological imaging followedby biopsy. A clinico-pathological profile was made from thedata obtained from these patients. Patients were treated eitherby surgery, radiotherapy or chemotherapy or a combination asappropriate and followed up regularly.Results: There were 27 males and 13 females in the presentstudy with a male: female ratio of 2:1. Commonest age groupwas 11 to 20 years. Maximum number of patients encounteredwere students (30%) followed by domestic workers (20%).Nasal obstruction and epistaxis were the most commonmode of presentation (65% each). Out of 40 cases, 25 (62%)had benign and 15(38%) had malignant tumour. Juvenileangiofibroma and maxillary carcinoma were the most commonunder the benign and malignant varieties of sinonasal tumoursrespectively.Conclusion: Timely diagnosis and early treatment willdecrease the burden of morbidity and mortality in thesepatients. This study recommends awareness regarding thedisease process and health education to people regardingmaintenance of hygienic conditions and utilization of healthfacilities.

Locally Advanced Staged Juvenile Nasopharyngeal Angiofibroma Treated with Endoscopic Endonasal Approach and Angio-embolization at a Tertiary Institution in Jamaica / Angiofibroma nasofaríngeo juvenil en etapa localmente avanzada tratado con un enfoque endonasal endoscópico y angioembolización en una institución terciaria en Jamaica

ABSTRACT Locally advanced staged juvenile nasopharyngeal angiofibroma (JNA) traditionally treated with external approaches has been associated with significant morbidities such as blood loss with subsequent blood transfusions, scars, impaired speech, poor swallowing, recurrence and prolonged hospital stays. This case report describes our initial experience in a patient with a locally advanced JNA treated with endonasal endoscopic approach and angio-embolization at Kingston Public Hospital, Jamaica, with subsequent benefits.

RESUMEN El angiofibroma nasofaríngeo juvenil (ANJ) en etapa localmente avanzada, tratado tradicionalmente con enfoques externos, se ha asociado a morbilidades significativas, tales como pérdida de sangre con transfusiones subsecuentes de sangre, cicatrices, trastornos del habla, pobre deglución, recurrencia y estancias hospitalarias prolongadas. Este reporte de caso describe nuestra experiencia inicial con un paciente con ANJ localmente avanzada tratado con un enfoque endonasal endoscópico y angioembolización en el Hospital Público de Kingston, Jamaica, con beneficios subsiguientes.

Challenges in the Management of a Child with Yolk Sac Tumour of the Nasal Cavity Presenting with Epistaxis and Progressive Respiratory Distress

@#Yolk Sac tumour (YST) of the nasal cavity is extremely rare with only less than five previously reported cases in the English literature. Due to its rarity, the diagnosis is not one that is considered at initial presentation until tissue biopsies are sent for histopathological examination. Serum α-fetoprotein levels aid in diagnosis and in monitoring progression of the tumour. Being a very uncommon tumour of germ cell origin presenting as localized disease in the nasal cavity, prognosis and survival rates are difficult to determine. We are reporting a rare yolk sac tumour case in an infant and the challenges encountered in its management.