Comparison and Repeatability of Anterior Segment Parameters Obtained by Galilei and Slit-lamp Optical Coherence Tomography

PURPOSE: To evaluate the repeatability and comparability of anterior chamber depth (ACD) and central corneal thickness (CCT) measurements obtained by Galilei dual Scheimpflug analyzer (Ziemer, Port, Switzerland) and slit-lamp optical coherence tomography (SL-OCT; Heidelberg Engineering, Dossenheim, Germany). METHODS: ACD and CCT were measured by Galilei and SL-OCT in 68 eyes of 68 healthy young subjects. Each measurement was performed 3 times by a single examiner, and the repeatability of 3 consecutive measurements was analyzed. ACD and CCT measurements were compared between the 2 devices. RESULTS: Both Galilei and SL-OCT showed high repeatability (ICCs > or = 0.994) for ACD and CCT measurements. The mean ACD and CCT measured by Galilei were greater than SL-OCT measurements by 0.11 +/- 0.09 mm and 14.01 +/- 7.38 microm, respectively. The 95% limit of agreement values for ACD and CCT measurements were 0.36 mm, 27.66 microm, respectively, and were highly correlated (correlation coefficients > or = 0.89, p < 0.001). CONCLUSIONS: Although the repeatability of each device was high, ACD and CCT obtained by Galilei and SL-OCT were significantly different. These differences should be considered when interpreting ACD and CCT measurements obtained by the 2 devices.

Agreement of anterior chamber angle examination by slit lamp optical coherence tomography and gonioscopy / 眼科

Objective To explore the agreement of anterior chamber angle examination by slit lamp optical coherence tomography (SL-OCT) and gonioscope.Design Case series.Participants Thirteen patients with primary glaucoma (26 eyes) and 8 normal persons(16 eyes).Methods Anterior chamber angle was measured with SL-OCT and gonioscope in turns for temporal,nasal,superior and inferior quadrant.Results of two methods were analyzed and the data were analyzed with Pearson correlation coefficient and Kappa value.Main Outcome Measures Anterior chamber angle.Results The Pearson correlation coefficient of the two methods was 0.86(P=0.00)and the Kappa value is 0.75 (P=0.00).The specificity and sensitivity of detecting occludable angle were 94.7% and 89.4%.Conclusions Anterior chamber angle examination with SL-OCT and gonioscope are well consistent.The specificity and sensitivity for SL-OCT in detecting occludable angle is satisfying.SL-OCT can be regard as an objective assistant method for the diagnosis of angle closure glaucoma.