1.
Chinese Journal of Endocrinology and Metabolism
;
(12): 468-470, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-468588
ABSTRACT
Diabetic nephropapthy (DN) is a common cause of end-stage renal disease.Early diagnosis and treatment are significant for delaying the development of DN.Smad proteins mediate transforming growth factor β superfamily intracellular signal transduction.Recent studies have found that Smad1 protein plays an important role in the process of renal fibrosis.Urine Smad1 emerges in the early stage of DN,which is expected to be a non-invasive indicator in early diagnosis of DN.