Características clínicas de Soiling en pacientes postoperados de enfermedades anales en el Hospital General San Juan de Dios / Clinical settings of patients with postoperative Soiling at San Juan de Dios Hospital

Introducción: El soiling es el escape inconsciente de pequeñas cantidades de materia fecal después de una evacuación normal. Se ha reportado una prevalencia del 7-23% en otros países y se ha observado una alta incidencia después de esfinterotomías y fistulotomías (35-45%). Material y Métodos: Se realizó un estudio observacional que incluyó 80 pacientes con patologías anales que acudieron a la consulta externa del Hospital General San Juan de Dios donde se aplicó un cuestionario de 8 ítems. Resultados: Se evaluaron 80 pacientes, la mayoría son hombres, de la quinta década. La enfermedad anal más frecuente son las hemorroides y el tratamiento quirúrgico más frecuente la hemorroidectomía. La incidencia de soiling definitivo (presencia de manchado a los 6 meses) es del 22.5%. Las variables asociadas fueron el género masculino, el tipo de enfermedad y procedimiento quirúrgico, el enrojecimiento, la picazón anal, el uso de protector en la región anal, la sensación de materia fecal y la limpieza en región anal. El ser hombre presenta un riesgo 6 veces mayor y el presentar enrojecimiento en la región anal aumenta el riesgo de 27 veces de presentar soiling definitivo. Conclusión: El soiling se presenta en un quinto de los pacientes que son operados de patologías anales en el Hospital General San Juan de Dios. La presencia de eritema, picazón anal, el uso de protector en la región anal, la sensación de materia fecal y la limpieza en región anal son variables estadísticamente asociadas al mismo. (AU)

Introduction: Soiling is the unconscious escape of small amounts of fecal matter after a normal bowel movement. A prevalence of 7-23% was reported in other countries and a high incidence was observed after sphincterotomies and fistulotomies (35-45%). Material and Methods: A observational study that included 80 patients with anal pathologies who attended the outpatient clinic of the San Juan de Dios General Hospital during 2018-2019, where an 8-item questionnaire was applied. Results: Eighty patients were evaluated, the majority are men, in their fifth decade. The most common anal disease is hemorrhoids, and the most common surgical treatment is hemorrhoidectomy. The incidence of definitive soiling (presence of spotting at 6 months) is 22.5%. The variables associated with definitive soiling were male gender, type of disease and surgical procedure, redness, anal itching, use of a protector in the anal region, the sensation of fecal matter, and cleanliness in the anal region. Being male presents a 6 times greater risk of definitive soiling and having redness in the anal region presents a 27 times greater risk of definitive soiling. Conclusion: Soiling occurs in a fifth of the patients operated for anal pathologies at the San Juan de Dios General Hospital. The presence of erythema, anal itching, the use of a protector in the anal region, the sensation of stool, and cleanliness in the anal region are statistically associated variables with soiling. (AU)

Socio-Demographic Characteristics and Predictors of Childhood Primary Nocturnal Enuresis in Benin City, Nigeria.

Aim: To document the socio-demographic characteristics and predictors of primary nocturnal enuresis in children. Study Design: A descriptive cross sectional study. Place and Duration of Study: The study was carried out in public primary and secondary schools in Egor Local Government Area, Edo State, Nigeria from April to August 2014. Participants and Methods: A semi-structured self-administered questionnaire was used to obtained information about nocturnal enuresis from 1221 mothers/child pair who gave consent to participate in the study. Results: Prevalence of primary nocturnal enuresis in the children was 18.8% (primary monosymptomatic nocturnal enuresis 73.7% and primary non- monosymptomatic nocturnal enuresis 26.3%). Children ages 5 – 7 years (OR = 5.0, p = 0.00) and those from the large household (20.3%) (p = 0.02) significantly had primary nocturnal enuresis. Predictors of primary nocturnal enuresis in this study included difficulty to awaken child from sleep (β = 0.90, OR = 2.5, p = 0.00), history of soiling under-wear (β = 1.56, OR = 5.0, p = 0.00), urgency (β = 1.0, OR = 2.7, p = 0.00), and family history of enuresis (β = 1.95, OR = 7.0, p = 0.00). Conclusion: This study showed that about one out of every five school children had primary nocturnal enuresis. Difficulty to awaken child from sleep, soiling of under-wears, history of urgency and family history independently predicted primary nocturnal enuresis.

Conceptos actuales de patología anorrectal funcional / Current concepts in functional anorectal disorders

The purpose of the present article is to highlight relevant aspects of anorectal pathology, mainly fiber resistant constipation, fecal incontinence and fecal soiling. A high percentage of patients with fiber resistant constipation correspond to dyssynergic defecation cases. In addition, most patients with dyssinergia and slow colonic transit return to normal after correction of the dyssyinergic condition. For these reasons, the current recommendation is to consider the evaluation of dyssynergic defecation as the initial diagnostic approach in patients with laxative-resistant constipation. Rectal hyposensitivity is an important pathophysiological mechanism involved in both constipation and fecal incontinence. About 80% of fecal incontinence cases present multiple pathological mechanisms, including sphincter insufficiency, rectal hyposensitivity, poor rectal emptying and impaired rectal compliance. Soling and seepage are usually in the context of poor rectal emptying and not in the context of sphincter insufficiency.

El siguiente artículo pretende destacar aspectos relevantes en patología anorrectal funcional, principalmente constipación resistente a fibra, incontinencia fecal y ensuciamiento. Entre los pacientes con constipación resistente a fibra, un alto porcentaje corresponde a defecación disinérgica. Además, la mayoría de los pacientes con defecación disinérgica y tránsito colónico enlentecido normalizan el tránsito tras mejoría de la disinergia. Por estos motivos, la recomendación actual es la evaluación de defecación disinérgica como primera estrategia diagnóstica en los pacientes con constipación refractaria a laxantes. La hiposensibilidad rectal es un mecanismo importante en casos de constipación e incontinencia fecal. Alrededor de 80% de los casos de incontinencia fecal tienen múltiples mecanismos descritos, incluyendo insuficiencia esfinteriana, hiposensibilidad rectal, mal vaciamiento rectal y alteraciones de la complianza rectal. El ensuciamiento suele estar en el contexto de mal vaciamiento rectal y no en el contexto de insuficiencia esfinteriana.

Gastric emptying of water in children with severe functional fecal retention

The objective of this study was to evaluate gastric emptying (GE) in pediatric patients with functional constipation. GE delay has been reported in adults with functional constipation. Gastric emptying studies were performed in 22 children with chronic constipation, fecal retention and fecal incontinence, while presenting fecal retention and after resuming regular bowel movements. Patients (18 boys, median age: 10 years; range: 7.2 to 12.7 years) were evaluated in a tertiary pediatric gastroenterology clinic. Gastric half-emptying time of water (reference range: 12 ± 3 min) was measured using a radionuclide technique immediately after first patient evaluation, when they presented fecal impaction (GE1), and when they achieved regular bowel movements (GE2), 12 ± 5 weeks after GE1. At study admission, 21 patients had reported dyspeptic symptoms, which were completely relieved after resuming regular bowel movements. Medians (and interquartile ranges) for GE1 and GE2 were not significantly different [27.0 (16) and 27.5 (21) min, respectively (P = 0.10)]. Delayed GE seems to be a common feature among children with chronic constipation and fecal retention. Resuming satisfactory bowel function and improvement in dyspeptic symptoms did not result in normalization of GE data.

Características clínicas asociadas al escurrimiento fecal ''soiling'' en pacientes operados de enfermedades anales / Clinical characteristics associated to fecal ''soiling'' in patients subjected to anal surgeries

Objetivo: Describir las características clínicas relacionadas con el escurrimiento fecal ''soiling'' que presentan los pacientes operados de enfermedad hemorroidal, fístula, fisura anal y drenaje de absceso. Sede: Unidad de Coloproctología del Servicio de Gastroenterología del Hospital General de México ''Dr. Eduardo Liceaga''. Diseño: Estudio de casos y controles. Análisis estadístico: Medidas de tendencia central, t de Student, cálculo de momios (odds ratio; OR) y análisis no paramétrico con χ². Pacientes y métodos: Se aplicó un cuestionario de ocho ítems a 132 pacientes que acudieron a la consulta externa de nuestra unidad. El manchado de ropa interior, eritema anal, cicatriz, prurito y utilización de material para proteger la región anal, así como el cambio de alimentación, la presencia de materia fecal en el ano y la limpieza de la región anal sin haber evacuado fueron las variables evaluadas y comparadas entre pacientes operados y no operados. Resultados: Se incluyeron 59 hombres y 73 mujeres con edad media de 45 años, 58 pacientes operados y 74 no operados. El manchado de ropa interior fue el síntoma más frecuente en los pacientes operados (37% versus 25%). Las otras variables con significancia estadística, al compararse ambos grupos, fueron: prurito, la presencia de una cicatriz y eritema anal. El OR para cirugía en pacientes con manchado de ropa fue 3.22 (95% IC 1.57-6.60), para prurito 2.24 (95% IC 1.11-4.52) y la presencia de una cicatriz anal 91.38 (95% IC 24.46-341.43). Conclusiones: El soiling caracterizado como manchado de la ropa interior se presenta en al menos un tercio de los pacientes operados de cirugía anal. La presencia de eritema, materia fecal en el ano y una cicatriz anal asociadas hacen pensar en esta alteración.

Objective: To describe the clinical characteristics related to soiling present in patients subjected to anal surgery due to hemorrhoidal disease, fistula, anal fissure, and abscess drainage. Setting: Coloproctology unit of the Gastroenterology Service of the General Hospital of Mexico ''Dr. Eduardo Liceaga''. Design: Cases and controls study. Statistical analysis: Central tendency measures, Student's t test, odds ratio (OR) and non-parametric analysis using χ². Patients and methods: We applied an eight-item questionnaire to 132 patients that came to the out-patient consultation of our unit. Soiling of underwear, anal erythema, scar, pruritus, use of material to protect the anal region, change in feeding habits, presence of fecal matter in the anus, and cleaning of the anal region without having defecated were the assessed variables and these were compared between operated and non-operated patients. Results: We included 59 men and 73 women, average age of 45 years, 58 operated and 74 non-operated. Soiling of underwear was the most frequent sign in operated patients (37% versus 25%). The other variables with statistical significance when comparing both groups were: pruritus, presence of a scar and anal erythema. The OR for surgery in patients with underwear soiling was 3.22 (95% CI 1.57-6.60); for pruritus, 2.24 (95% CI 1.11-4.52) and presence of anal scar, 91.38 (95% CI 24.46-341.43). Conclusions: Soiling of underwear was found in at least one third of patients subjected to anal surgery. The presence of erythema, fecal matter in the anus, and an anal scar should lead to consider this alteration.

Constipação intestinal / Constipation

A constipação intestinal crônica é motivo comum de consulta em ambulatório de pediatria e de gastroenterologia pediátrica. A apresentação clínica é variável. A procura para tratamento é tardia, em geral quando surgem as complicações da doença, como a encoprese, o escape fecal e a dor abdominal. Alguns fatores são importantes na fisiopatologia como alimentação, predisposição genética, desmame precoce, dismotilidade intestinal, comportamento de retenção fecal, ocorrência de evacuação com dor ou sangue. As causas de constipação intestinal podem ser orgânicas ou funcionais. Em uma pequena parcela dos casos é necessária a solicitação de exames complementares para o diagnóstico definitivo. O tratamento é prolongado e depende da adesão dos pacientes e dos seus responsáveis. Algumas vezes, o médico deverá intervir na dinâmica familiar, modificando hábitos alimentares e de vida, motivando o uso dos medicamentos, quando prescritos, prevenindo a recorrência dos sintomas.

Constipation is a frequent complaint in pediatric and gastroin-testinal pediatric visits. Clínica I presentation may vary. Search of medical assistance for treatment is delayed, general/y occurring at the onset of complications such as soilíng, encopresis or abdominal pain. Associated factors in constipation physiopa- thology include low fiber diet, genetic predisposition, intestinal dismotility, fecal retentive behavior, ear/y weaning, painful defe- cation and presence of blood in feces. One must always investigate the cause of constipation as anatomic abnormalities and organic diseases may be present. Diagnosis is general/y based on medical history and physical examination, especial/y in chronic functional constipation. Complíance to long term treatment by patient and fami/y is necessary. The attending pediatrician must be prepared to motivate both patient and family regarding use of medication and changing diet habits. The pediatrician must identify the need and opportune timing for further diagnostic testing and interventions.

Fecal Soiling Manometric findings and treatment

BACKGROUND: Fecal continence is maintained by complex coordination of the sphincter mechanism and the anorectal sensation. Although most patients with fecal incontinence have a dysfunction of anal sphincter, fecal soiling seems to be related with a change in the anorectal sensation. PURPOSE: This study was done to evaluate the manometric findings and the methods of treatment for patients with fecal soiling. METHODS: The manometric findings from 25 patients with fecal soiling were compared with those from 22 normal controls. The patients were treated with biofeedback and with bulking agent. RESULTS: All the patients affected by fecal soiling were male except for one. There were no differences in the mean maximal resting pressure (MRP), and the mean maximal squeezing pressure (MSP) between the patients and the controls. The mean sphincter length and the mean length of the high pressure zone (HPZ) of the patients were significantly longer (50.5 vs. 55.6 mm and 28.2 vs. 31.3 mm, respectively; p<0.05 student t-test) than those of the controls. The minimal sensory volume (MSV) was significantly larger in the patient group, with a mean of 24.2 ml vs. 17.8 ml, than in the control group (p<0.05). The mean volume necessary to induce the recto-anal inhibitory reflex (RR) was 47.1 ml for the control group and 32.6 ml for the patient group (p<0.05). In the longitudinal profile of the anal sphincter, the HPZ was shifted proximally and the pressure peak was broader in the fecal soiling group. Of the 14 patients treated with biofeedback, 11 responded well. CONCLUSION: Almost all of the patients affected by fecal soiling were men. The MRP and the MSP of the patients with fecal soiling were not lower than those of the normal controls. The sphincter length was longer in the patients with soiling than in the controls(p<0.05). However, for the fecal soiling group the distribution of the pressure along the anal canal was different in the sense that the HPZ was shifted proximally and the pressure peak was broader. The changes in the MSV and the RR suggest that there may be a defect in the anorectal sensation. The patients responded well to the combined use of biofeedback and a bulking agent.