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Annals of Laboratory Medicine ; : 283-287, 2013.
Article in English | WPRIM | ID: wpr-105284

ABSTRACT

Sphingobacterium spiritivorum has been rarely isolated from clinical specimens of immunocompromised patients, and there have been no case reports of S. spiritivorum infection in Korea to our knowledge. We report a case of S. spiritivorum bacteremia in a 68-yr-old woman, who was diagnosed with acute myeloid leukemia and subsequently received chemotherapy. One day after chemotherapy ended, her body temperature increased to 38.3degrees C. A gram-negative bacillus was isolated in aerobic blood cultures and identified as S. spiritivorum by an automated biochemical system. A 16S rRNA sequencing analysis confirmed that the isolate was S. spiritivorum. The patient received antibiotic therapy for 11 days but died of septic shock. This is the first reported case of human S. spiritivorum infection in Korea. Although human infection is rare, S. spiritivorum can be a fatal opportunistic pathogen in immunocompromised patients.


Subject(s)
Aged , Female , Humans , Anti-Bacterial Agents/therapeutic use , Bacteremia/complications , Bone Marrow Cells/pathology , Fatal Outcome , Immunocompromised Host , Leukemia, Myeloid, Acute/complications , Phylogeny , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNA , Shock, Septic/etiology , Sphingobacterium/classification
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