ABSTRACT
Spiny keratoderma is a dermatosis consisting of multiple projections located on the palms and soles with a distinct histology characteristic of a parakeratotic column. This disease has been associated with various underlying benign or malignant diseases. We report a case of a 72-year-old female patient with spiny keratoderma associated with diabetes mellitus and hypothyroidism.
Subject(s)
Aged , Female , Humans , Diabetes Mellitus , Hypothyroidism , Skin DiseasesABSTRACT
Spiny keratoderma is a rare disorder and consists of multiple tiny keratotic plugs on the fingers and palms, which resemble the spines on a music box. Histopathologically, the lesions show compact columns of parakeratosis, with no granular layer beneath the column and no remarkable changes in the underlying epidermis and dermis. However, it is important to recognize that the disease is associated with internal malignancies. We report a case of spiny keratoderma in a 3-year-old girl, who had no associated underlying disorder.