DESCARTES and his project of a fantasized brain / DESCARTES e seu projeto de um cérebro fantasioso

ABSTRACT. Interest in anatomy dates from the earliest times. Such knowledge was acquired through dissections of animals and human corpses by many researchers. The macroscopic anatomy of the varied structures of the brain were identified over the centuries, and the predominating solid substance was seen as amorphous, and devoid of any specific function, until the Renaissance. René Descartes, a personage with a brilliant and creative mind, conceived the brain, its structure and function, in a distinct manner to what was known at his time. He valued the solid matter and gave it, for the first time, a theoretical minute structure, related to a presumptive function based on the presence of the pineal gland and the animal spirits, underlying cognitive, sensory and motor activities. Such structural view was endorsed, in a given sense, by the microscopic findings of Marcello Malpighi, which begun to change the understanding of the nervous system.

RESUMO. O interesse pela anatomia data desde a mais remota antiguidade. Esse conhecimento foi adquirido por meio de dissecções em animais e cadáveres humanos, por muitos pesquisadores. A anatomia macroscópica de variadas estruturas do cérebro foi identificada com o passar dos séculos, e a substância sólida predominante foi vista como amorfa e destituída de qualquer função específica até o período do Renascimento. René Descartes, um personagem com uma mente brilhante e criativa, concebeu o cérebro, sua estrutura e função, de um modo distinto ao que era conhecido no seu tempo. Ele valorizou e deu à substância sólida, pela primeira vez, uma estrutura teórica formada por elementos minúsculos, relacionada a uma função presuntiva, baseada na presença da glândula pineal e dos espíritos animais, subjacentes às atividades cognitiva, sensorial e motora. Essa vista estrutural foi, de certa maneira, endossada pelos achados microscópicos de Marcello Malpighi, o que começou a modificar a compreensão do sistema nervoso.

Discussion on traditional Chinese medicine treatment models of depression named "three phases, five internal organs and ten syndromes" / 国际中医中药杂志

Based on the inheritance, the research group summarized the transmissive pathogenesis of depression in three typical stages, formulating the stepward treatment units which included Chinese medicine, acupuncture and TCM characterized psychotherapy, and formed a sequential treatment plan that balanced the principle of strengthening healthy Qi to eliminate pathogens, active and passive treatment, physical therapy and psychotherapy. Based on the retrospective analyses, ten typical clinical syndromes have been formed, constituting the pattern differentiation of "Three Phases, Five internal organs and Ten syndromes" for depression, which sysmatically showed the TCM syndrome differentiation. This work promoted the experiences and methods of treating depression by Chinese medicine.

An Analysis of Acupuncture Treatment on Regulating Spirits of Patients Accepting IVF-ET / 浙江中医药大学学报

Objective] To analyze the effect of acupuncture treatment on regulating patients’spirits who accepted IVF-ET surgery, in order to provide a new train of thought for clinical treatment. [Methods] Based on emotional factors, analyze the condition of patients accepting IVF-ET surgery. Explaining that spirit is also an important factor, can not be ignored during pregnancy and expounding the theory and prescription of acupuncture treatment on regulating spirits in patients with infertility, and in the clinical cases, patients undergoing IVF-ET can get active treatment by regulating spirits.[Results] Acupuncture treatment on regulating spirits to remove patients’depression and anxiety by regulating qi and blood, also nourishing heart and tranquilizing mind, so, this treatment can create conditions for conception. The clinical case cited also achieved good results. [Conclusions] This treatment,as a natural non-drug therapy,can be considered as a new train of thought in clinical treatment of patients with infertility after IVF-ET surgery and is worthy of research.

Determination of Two Components in A-Liu Spitits and Their Stability under Different Storage Conditions / 中国药师

Objective:To establish an HPLC method for determining the content of aspirin and sodium salicylat in A-Liu spirits and study the stability of the two components under different storage conditions. Methods:The analytical column was Agilent Eclipse XDB-C18(150 mm ×4.6 mm, 5 μm) ,0.01 mol·L-1 potassium dihydrogen phosphate (adjusting pH to 2.3 with potassium acid) -acetonitrile-methanol(55∶15∶30) was used as the mobile phase at the flow rate of 1. 0ml·min-1 , the detection wavelength was 280 nm and the column temperature was 30℃. The contents of aspirin and sodium salicylat were regularly determined under such storage conditions as ambient temperature, constant temperature and humidity(30℃ ± 2℃,65% ± 5%) and refrigeration (4℃ ± 2℃). Re-sults:The average recovery and RSD were 100. 06% and 0. 80%(n=9) for aspirin, and 100. 53% and 0. 82%(n=9) for sodium salicylat. Aspirin and sodium salicylat showed good linear relationship within the range of 31.0-310.0 μg·ml-1(r=0.999 9)and 30. 5-305. 0 μg·ml-1(r=0. 999 5), respectively. Under the three storage conditions, the content of aspirin was decreased, while that of sodium salicylat was increased, suggesting the temperature could significantly affect the hydrolysis rate and content of aspirin Conclusion:The method is promising with good resolution, reproducibility and sensitivity. It is recommended that the method be used to determine the content of aspirin and sodium salicylat in A-Liu spirits, and aspirin isn't stable under different storage conditions.

The Spirits of A Great Physician and Bioethics Integrate into Ideological and Moral Education of Medical Students / 中国医学伦理学

The emerging technologies change rapidly in the medical field, refresh the medical ethical scenari-os, brought some medical ethical blind spot.Therefore, building the platform of academic research, making use of the new media, MOOC and“flipped classroom”, inheriting the native“The Spirits of A Great Physician” in tradi-tional Chinese medicine and western medicine, life ethics education and sublation of new exploration, the ideolog-ical and moral education for medical students is expected to be improved in China.

Simultaneous Determination of Chloromycetin and Metronidazole in Chlortalidone and Metronidazole Spir-its by HPLC / 中国药师

Objective: To establish an HPLC method for the simultaneous determination of chloromycetin and metronidazole in chlortalidone and metronidazole spirits. Method:The HPLC method was performed on an NOV-pak C18 (150 mm × 4. 6 mm, 5 μm) column and the mobile phase consisted of methanol and water (75∶25). The flow rate was 1. 0 ml·ml-1, the detection wavelength was 297nm, the temperature of column was 30℃ and the sample size was 20 μl. Result: The calibration curve of metronidazole was linear within the range of 5-80μg·ml-1(r=0. 999 7), and the average recovery was 100. 83% with RSD of 1. 82%(n=6). The cal-ibration curve of chlortalidone was linear within the range of 50-800μg·ml-1(r=0.999 7), and the average recovery was 100.2%with RSD of 0. 55%(n=6). Conclusion: The method is simple, rapid, accurate and reproducible, and can be used in the quality control of chlortalidone and metronidazole spirits.

Avatares da ressurreição dos mortos / Metamorphosis of the resurrection of deaths

Este artigo sublinha a singularidade da invenção da crença na ressurreição dos mortos: esta é aqui examinada sob o ângulo das concepções freudianas do objeto perdido e do luto. A história dessa invenção é retomada desde sua emergência nos primeiros textos bíblicos, seguida de seu florecimento particular com as assombrações, na Idade Média, até seu desenrolar no período moderno e suas manifestações na clínica.

This paper underlines the singularity of the invention of the belief in the resurrection of deaths: this one is examined here taking into consideration Freudian design of the lost object and mourning. The history of this invention is taken again since its emergence in the first biblical texts, its particular efflorescence, with the ghosts, during the Middle Age, until his becoming with the modern period and its expressions in the clinic.

Physico-chemical and sensorial evaluation of sugarcane spirits produced using distillation residue

The objective of the present study was to analyze the use of vinasse from cachaça as an ingredient of the fermentation medium for the spirit production. The fermentations were conducted out in three successive batches using a Saccharomyces cerevisiae isolate. In the first batch, the sugarcane broth was only diluted with distilled water. In the second and third batches, the fermentations were carried out using the cane broth diluted with vinasse from the distillation of the sugarcane wines of the first and second batches, respectively at a concentration of 10% (v/v). The spirits were submitted to the physicochemical and sensorial analyses. The results showed that vinasse addition did not affect the fermentation, distillation and chemical-sensorial quality of the beverage. Therefore, the vinasse addition could be an alternative use for that residue.

On discussing the fostering of medical humanistic spirits for students majoring medical science of law / 中华医学教育探索杂志

Shortages in the fostering of medical humanistic spirits for students majoring medical science of law in medical colleges and universities were discussed from the perspectives of concept establishment,curriculum,clinical teaching and teaching staff.The fostering of medical humanistic spirits for students should be enhanced to achieve the balance between medical humanity and legal professionalism.

Saúde e doença em Moçambique / Health and illness in Mozambique

Baseando-se num longo período de observação directa e entrevistas, este artigo aponta como principal obstáculo às pouco frutuosas tentativas de diálogo entre biomedicina e "medicina tradicional", em Moçambique, o desconhecimento e/ou desvalorização das noções locais acerca da doença, vertentes sociais da sua etiologia e suas implicações para a noção e processo de cura. Assim, a par da caracterização dos tinyanga (terapeutas putativamente possuídos por espíritos) e das terapias que utilizam, o artigo expõe o sistema localmente dominante de interpretação dos infortúnios, em que as causas materiais (como aconteceu) se combinam com factores sociais ou espirituais (porque aconteceu àquela pessoa). Daí decorre que o processo de cura não se esgota no debelar da enfermidade, implicando também a resolução do problema social do qual ela é uma manifestação - o que constitui uma das especialidades destes terapeutas. Por isso, nem o recurso a tinyanga resulta sobretudo de falta de alternativas de cuidados de saúde, nem é concebível, para estes terapeutas, que o seu entrosamento com o sistema de saúde oficial pudesse restringi-los à sua faceta de herbalistas. Contudo, o debate e negociação do seu espaço, papel e estatuto dentro de futuros quadros gerais de prestação de cuidados de saúde não deverão ser feitos através de "tradutores culturais" bem intencionados, que lhes pretendam "dar voz". Os próprios tinyanga dispõem das capacidades e competência para o fazer, assim tenham interlocutores.

Based on a long process of direct observation and interviews, this article states that the main barrier to the unfruitful attempts of dialog between biomedicine and "traditional healers", in Mozambique, is the ignorance and/or undervaluation of the local notions about illness, the social aspects of its aetiology, and their implications for the notion and process of cure. Therefore, together with the characterization of the tinyanga (healers putatively possessed by spirits) and their therapies, the article presents the locally dominant system of misfortune interpretation, in which the material causes (how it happened) are combined with social and spiritual factors (why it happened to that person). As a consequence, the cure is not only the healing of the illness; it includes and demands as well the resolution of the social problem that caused it - and this second aspect of the cure is one of the tinyanga's expertises. For that reason, consulting such healers seldom results from the absence of health care alternatives, and they cannot accept the idea of being limited to their herbalist expertise, in order to be integrated into the official health care system. However, the debate and negotiation about their space, role and status in future general health care systems should not be made through sympathetic "cultural translators". The tinyanga have the abilities to do it with their own voice, as far as they have available interlocutors.

Modern Universities Call on Humanistic Education / 中华医学教育探索杂志

Humanistic education is the important content of college quality education.But the humanistic education in our country is very weak,and the university students are short of humanistic spirits at large,which goes against the improvement of the quality of university students and higher education.So our universities should enhance humanistic education,which should be the keystone of stratage for each university from ideas to practice.

Discussion on the Educaion of Medical ethics on Medical Laboratory Technicians / 中国医学伦理学

This article discusses the ethical problems which appear when medical laboratory technicians deal with all kinds of interpersonal relations in the field of medicine from the point of present medical service.It advocates that medical staff should possess professional morality and the sense of duty and calls for humane spirits to set up a brand-new mode of medical ethics.

Determinação de álcoois superiores em aguardentes de frutas por cromatografia em fase gasosa / Gas-liquid chromatographic determination of higher alcohols in fruit distilled spirits

Cromatografia em fase gasosa com detector de ionização de chama foi aplicada para a pesquisa e dosagem de álcoois superiores em aguardentes de ameixa (slivovitz) provenientes da Iugoslávia, em aguardentes de uva (pisco) provenientes do Chile e em aguardentes de banana, do Brasil. Em todas as amostras foram encontrados os álcoois n-propanol, isobutanol e isoamílico. Nas amostras de slivovitz também foram identificados os álcoois n-butanol e 2-butanol, o mesmo ocorrendo em algumas amostras de pisco. A determinação dos álcoois foi efetuada pelo processo de padronização interna, com o emprego de 2-pentanol. Os teores de n-propanol, isobutanol e álcool isoamílico nas amostras de slivovitz variaram de um mínimo de 31,64; 14,20 e 38,10 a um máximo de 56,80; 31,20 e 78,80 mg/ml. respectivamente; nas amostras de pisco, variaram de 5,50; 9,40 e 33,40 a 18,50; 40,70 e 108,80 mg/100ml e, nas aguardentes de banana, variaram de 5,20; 14,00 e 45,60 a 7,00; 15,92 e 56,04 mg/100ml. Considerando os resultados obtidos, destacamos o alto teor de n-propanol em todas as amostras analisadas de slivovitz muito acima do encontrado nas aguardentes de uva e de banana por nós analisadas e dos teores referidos por diversos autores em outras bebidas fortemente alcoólicas (AU).