ABSTRACT
With the development of Internet medical service, the traditional peer-to-peer access mode is difficult to meet the rapidly growing business demand. By means of information technology, our hospital has built an Internet application access management platform, formed a " three platforms and one center" management model, formulated an application access standard management process based on integrated access documents, introduced a series of information security measures, and constructed a set of Omni-directional and standardized Internet application access management system. It has been proved that the system could realize unified design, standard access, centralized management, and security audit for application access, could effectively solve the problems of Internet application access, and could also provide powerful data support for hospital medical, teaching and research work.
ABSTRACT
OBJECTIVE: To establish an evidence-based evaluation process of off-label drug use with the guidance of evidence-based medicine to provide decision support for clinical application of off-label drug use. METHODS: With the guidance of evidence-based medicine, the evaluation process of off-label drug use was established according to the requirements of Cochrane handbook 5.1 and the GRADE system. RESULTS: A standardized evidence-based evaluation process was established as follows; first, search and retrieve the evidence; second, assess the risk of bias of the study; third, assess the quality of evidence; last, achieve a consensus on the recommendations of off-label drug use. CONCLUSION: The process of evidence-based evaluation of off-label drug use will provide scientific decision support for Pharmacy Administration Drug and Therapeutics Committee of hospital to decide the clinical application of off-label drug use. It will effectively regulate the management of off-label drug use.