ABSTRACT
OBJECTIVE:To observe the clinical efficacy and safety of Shuxuetong combined with acupuncture in the treat-ment of patients with stroke during recovery period. METHODS:80 patients with stroke during recovery period were selected and divided into observation group and control group,with 40 cases in each group according to random number table method. Control group received acupuncture,6 times a week. Observation group was additionally given Shuxuetong injection 6 ml added into 0.9% Sodium chloride injection 250 ml,ivgtt,qd,for one month. Clinical efficacy of 2 groups were observed as well as in-tracranial [arteriae cerebri anterior (ACA),middle cerebral artery (MCA),basilar artery (BA)] blood flow rate,neurological deficit score(NIHSS),cognitive ability(MMSE)score,Fugl-Meyer activity score and Fugl-Meyer balance score before and af-ter treatment. The occurrence of ADR was compared. RESULTS:Total effective rate of observation group was 95.0%,which was significantly higher than that of control group(70.0%),with statistical significance(P<0.05). Compared with before treatment, blood flow rate of ACA and MCA were increased significantly in observation group after treatment,and were higher than those of control group with statistical significance (P<0.05). NIHSS,MMSE,Fugl-Meyer activity score and Fugl-Meyer balance score of 2 groups improved significantly after treatment,the observation group was better than the control group,with statistical signifi-cance(P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Shuxuetong combined with acupuncture show signif-icant therapeutic efficacy,and improve intracranial blood flow rate and neurologic function with good safety.
ABSTRACT
@#Objective To investigate the long-term outcome of old stroke patients after rehabilitation. Methods 25 old hospitalized patients with first attack of stroke in recovery were followed up with Mini-mental Status Examination (MMSE), Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS), Brunnstrom stages of hemiplegia, modified Ashworth scale (MAS), range of motion (ROM) in hemiplegic ankle, manual muscle test (MMT) of quadriceps femoris, Berg balance scale (BBS), modified Barthel index (BI) and the Zarit burden interview (ZBI) for caregiver before rehabilitation, discharge, 6 and 12 months after discharge. Results The Brunnstrom stages of lower limbs, MAS of upper limbs improved (P<0.05) after 3-month rehabilitation in hospital, as well as the scores of BBS, BI and ZBI. As 6 and 12 months in home, the limb function remained stable, while the scores of BBS, MMSE, BI, SAS, and ZBI improved, but SDS fluctuated (P<0.05). Conclusion It is important to offer the long-term rehabilitation or consultation service when advocating old stroke patients early return to family or community, including psychological support and intervention.