ABSTRACT
Subcutaneous granuloma pyogenicum is a rare variant of granuloma pyogenicum. It is often difficult to diagnose based on its clinical features because it appears as a nonspecific deep nodule lacking the characteristic surface changes such as erosion or ulceration, which are the characteristics of common polypoid granuloma pyogenicum. A 28-year-old primigravida presented at 6 months' gestation with a 8-week history of an enlarging mass on the volar aspect of her left thumb. Histological examination revealed that a well-defined tumor nodule occupying the lower dermis and subcutaneous layer was composed of a proliferation of capillaries arranged in a distinct lobular architecture, which is the hallmark of all variants of granuloma pyogenicum. This case suggests additional evidence of the possible role of female sex hormones in the pathogenesis of subcutaneous granuloma pyogenicum.
Subject(s)
Adult , Female , Humans , Pregnancy , Capillaries , Dermis , Fingers , Gonadal Steroid Hormones , Granuloma , Granuloma, Pyogenic , Thumb , UlcerABSTRACT
Subcutaneous granuloma pyogenicum (SGP) is a rare variant of granuloma pyogenicum. In general, it appears as a single subcutaneous nodule with a slight tenderness. We report herein an unusual case of SGP arising from the left palm of an 11-year-old girl. Two mild-tender bean-sized reddish or flesh colored subcutaneous nodules on the lateral border of the left palm, and medial side of 5th left finger, respectively, were noted on physical examination. Histopathologic examination revealed the findings of lobular capillary hemangioma, characterized by localized proliferation of capillary lined by a single endothelial cell layer. Intralesional injection of triamcinolone acetonide (TA) were performed for the treatment. However two new erythematous nodules developed at another area of the left palm, which disappeared without any treatment.
Subject(s)
Child , Female , Humans , Capillaries , Endothelial Cells , Fingers , Granuloma , Granuloma, Pyogenic , Injections, Intralesional , Physical Examination , Recurrence , Triamcinolone AcetonideABSTRACT
A 51-year-old man had multiple nonspecific subcutaneous nodules and small red hemorrhagic papules on his trunk. Histopathologically, the subcutaneous nodules were shown to be lobular capillary hemangiomas with edematous stroma throughout the entire subcutaneous fat. Multiple subcutaneous granuloma pyogenicum is a rare variant of granuloma pyogenicum. The addition of cherry angioma in the same patient also makes it a very unusual case.