ABSTRACT
Superficial acral fibromyxoma (SAF) is an uncommon soft tissue tumor that has recently been showed to be a separate disease entity. It is most often located in the ungal region of the fingers and toes of middle-aged adults. It is histologically characterized by a slight to moderate cellular proliferation of spindle cells and stellate cells arranged in a random, storiform or fascicular pattern, within a myxoid, myxocollagenous or collagenous stroma with a prominent vasculature. The neoplastic cells show positive staining for CD34, CD99 and EMA, but negative staining for S100, HMB45, cytokeratin, smooth muscle actin (SMA) and desmin. We report here on a typical case of SAF that occurred on the left index finger of a 44-year-old man.
Subject(s)
Adult , Humans , Acetylmuramyl-Alanyl-Isoglutamine , Actins , Cell Proliferation , Collagen , Desmin , Fibroma , Fingers , Keratins , Muscle, Smooth , Negative Staining , Polysorbates , Squalene , ToesABSTRACT
Superficial acral fibromyxoma (SAFM) is a rare myxoid tumor that was first described in 2001. The presence of a very slow growing solitary tender mass in the subungual area is the typical clinical feature at presentation. Histopathologically, SAFM is composed of stellate cells in a myxocollagenous matrix with a poorly circumscribed margin. This tumor is thought to be benign, but its natural course is not fully understood. We describe a 15-year-old patient with recurrent SAFM and discuss the proper treatment and follow up.
Subject(s)
Adolescent , Humans , Fibroma , Follow-Up StudiesABSTRACT
Superficial acral fibromyxoma is a rare, distinctive soft tissue neoplasm most often located in the periungal region of the fingers and toes. This tumor was recently recognized as a distinct clinicopathological entity and since then quite a few cases have been reported. These tumors are composed of stellate and spindle cells arranged in a loose form, with a fascicular growth pattern, and occur mostly in middle-aged adults. However in our case, the lesion developed in 9-year-old male, who had a history trauma. Although the exact pathogenesis of superficial acral fibromyxoma has not yet been clarified, it is possible that the fibroblast hyperplasia in the lesion could be triggered by trauma. We suggest this case which occurred in a 9-year-old patient, triggered by trauma, is a peculiar and interesting event.