ABSTRACT
OBJECTIVE:To determine the concentration of borneol in blood after keeping Suxiao Jiuxin pills in healthy men's mouth by GC METHODS:HP-5 quartz elasticity capillary column(15m?0 53mmID) was used with nitrogen as the carrier gas,temperature of column was 85℃ The injector temperature and detector temperature were 180℃,200℃ respectively Naphthalene was used as internal standard RESULTS:The standard curve was linear within the concentration range of 50～1 000ng/ml of borneol,the calibrating equation was Y=-0 1 273+0 0 015X The recovery was (98 7?2 31)%,(RSD=2 76%,n=6) The peak of blood drug concentration was obtained in 15 min or so CONCLUSION:The method was simple,rapid,accurate and suitable for pharmacokinetic study of preparation containing borneol
ABSTRACT
AIM: To observe the short-term curative effect of Suxiao Jiuxin Pill on coronary heart disease (CHD) and angina pectoris. METHODS: 187 patients were divided into two groups at random:the treatment group with 105 cases and the control group with 82 cases. The treatment group was given Suxiao Jiuxin Pill 6 pills tid and the control group was given Compound Danshen Dripping Pill 6 pills tid orally. The treating period was 2 weeks. Before and after treatment angina pectoris was observed and electrocardiogram was determined. RESULTS: Suxiao Jiuxin Pill could significantly alleviate syndrome of CHD in patients, lessen electrocardiogram and decrease dosage of nitroglycerin. The total effective rate on angina pectoris and the effective rate in improving electrocardiogram was higher in treatment group than that in control group (P