Morphological characteristics and bilateral differences of youth U13, U15, U17 and U19 male football players / Características morfológicas y diferencias bilaterales de los jóvenes futbolistas masculinos U13, U15, U17 y U19

SUMMARY: An anthropometric and body composition analysis was conducted on 123 competitive young male football players of different age groups (U13; U15; U17 & U19) with at least 4 years of training load. 3D anthropometric measurement were performed by the NX-16 ([TC]2, 3D body scanner Cary, North Carolina). Body composition was measured by the bioelectrical impedance with InBody 720 (Biospace Ltd.). Anthropometric and body composition characteristics among different age groups and asymmetries between the left and right side of the upper and lower limbs were analysed for treated age groups. The results showed differences in anthropometric and body composition variables among all age groups in all observed variables (Height, Weight, Basal Metabolic Rate, Skeletal Muscle Mass, Body Fat Mass, Percent Body Fat, Abdominal Obesity Degree, Body Mass Index, Body Fat Mass, Skeletal Lean Mass and Fat Free Mass). The results also showed that young football players of age group U13 differed statistically in four (from 7) paired variables (Arm Lean Mass, Leg Lean Mass, Forearm Girth and Calf Girth), U15 in three variables (Upper Arm Girth, Thigh Girth and Calf Girth), U17 in five variables (Arm Lean Mass, Leg Lean Mass, Upper Arm Girth, Forearm Girth and Calf Girth) and U19 in four observed variables (Arm Lean Mass, Leg Lean Mass, Upper Arm Girth and Calf Girth). All of the age groups differed statistically in calf girth paired variables. Puberty time probably had an impact on the results, and in future research more focus should be placed on puberty characteristics variables.

Se realizó un análisis antropométrico y de composición corporal en 123 jugadores de fútbol masculino jóvenes competidores de diferentes grupos de edad (U13, U15, U17 y U19) con al menos 4 años de carga de entrenamiento. La medición antropométrica 3D se realizó con el NX-16 ([TC]2, escáner corporal 3D Cary, Carolina del Norte). La composición corporal se midió mediante la impedancia bioeléctrica con InBody 720 (Biospace Ltd.). Se analizaron las características antropométricas y de composición corporal entre los diferentes grupos de edad y las asimetrías entre los lados izquierdo y derecho de los miembros superiores e inferiores para los grupos de edad tratados. Los resultados mostraron diferencias en las variables antropométricas y de composición corporal entre todos los grupos de edad en todas las variables observadas (Talla, Peso, Tasa Metabólica Basal, Masa Muscular Esquelética, Masa Grasa Corporal, Porcentaje de Grasa Corporal, Grado de Obesidad Abdominal, Índice de Masa Corporal, Masa Grasa Corporal, Masa magra esquelética y Masa libre de grasa). Los resultados también mostraron que los jugadores de fútbol jóvenes del grupo de edad U13 diferían estadísticamente en cuatro (de 7) variables pareadas (masa magra del brazo, masa magra de la pierna, circunferencia del antebrazo y circunferencia de la pantorrilla), U15 en tres variables (circunferencia del brazo superior, circunferencia del muslo y circunferencia del muslo). Circunferencia de la pantorrilla), U17 en cinco variables (Masa magra del brazo, Masa magra de la pierna, Circunferencia del brazo superior, Circunferencia del antebrazo y Circunferencia de la pantorrilla) y U19 en cuatro variables observadas (Masa magra del brazo, Masa magra de la pierna, Circunferencia del brazo superior y Circunferencia de la pierna). Todos los grupos de edad difirieron estadísticamente en las variables pareadas de circunferencia de la pierna. El tiempo de la pubertad probablemente tuvo un impacto en los resultados, y en investigaciones futuras se debe prestar más atención a las variables de las características de la pubertad.

Relationship between symmetry of lower limb function and gait symmetry in patients with incomplete spinal cord injury / 中国康复理论与实践

ObjectiveTo observe the characteristics of gait symmetry and its influencing factors in patients with incomplete spinal cord injury (ISCI). MethodsFrom May, 2018 to November, 2021, 34 patients with ISCI in Beijing Bo'ai Hospital were divided into symmetrical injury of lower limb (SI) group and asymmetrical injury of lower limb (ASI) group according to the lower extremities motor score (LEMS). Three dimensional motion acquisition system and plantar pressure acquisition system were used for gait test. The symmetry indexes of step length, stance time and swing time were caculated. ResultsThe symmetry indexes of step length, stance time and swing time were significant lower in SI group than in ASI group (|t| > 2.619, P < 0.01). Stance time and swing time significantly correlated to the difference of bilateral LEMS in ASI group (r > 0.468, P < 0.01). Discriminant analysis showed that gait parameter equations were different for patients with different symmetry of lower limb injuries. ConclusionThe symmetry of lower limb motor function impacts gait symmetry for patients with ISCI, especially the difference value of bilateral total LEMS. Gait parameters can be used to determine the symmetry of lower limb injury in patients with ISCI.

Effect of orthopedic elastic bandages on gait symmetry and walking ability in children with spastic hemiplegic cerebral palsy / 中国康复理论与实践

ObjectiveTo investigate the short-term efficacy of orthopedic elastic bandages on gait symmetry and walking ability in children with spastic hemiplegic cerebral palsy. MethodsFrom June, 2020 to June, 2023, 31 children with spastic hemiplegic cerebral palsy from Beijing Bo'ai Hospital were randomly divided into control group (n = 15) and experimental group (n = 16). Both groups received routine rehabilitation, while the control group received routine walking training, and the experimental group wore an orthopedic elastic bandage for walking training, for four weeks. The indexes of gait symmetry of foot deviation angle ratio (affected/healthy), step length ratio (affected/healthy), gait line ratio (affected/healthy) and standing stage ratio (affected percentage/healthy percentage) were calculated before and after training, and they were measured step width and the optional and maximum walking speed of 10-meter walk test (10MWT). ResultsOne case dropped off in the experimental group. After training, the foot deviation ratio, step length ratio, gait line ratio, and standing stage ratio improved in both groups (|t| > 2.434, P < 0.05), and they were better in the experimental group than in the control group (|t| > 2.230, P < 0.05); while the optional and maximum walking speed of 10MWT improved in both groups (|t| > 9.186, P < 0.001), and they were better in the experimental group than in the control group (|t| > 2.278, P < 0.05). ConclusionWearing orthopedic elastic bandages during rehabilitation can promote the gait symmetry and walking ability of children with spastic hemiplegic cerebral palsy.

A microprocessor-controlled prosthetic knee and its gait symmetry assessment / 中国康复理论与实践

ObjectiveTo present a method for evaluating the gait symmetry of microprocessor-controlled prosthetic knee (MPK). MethodsA kind of proto-MPK, AiKneeOne, and a wearable gait collect system, were made. The phases of the first double-limb support, the single-limb support, the second double-limb support, and the swing were used to calculate symmetry index (SI), ratio Ⅰ (RI) and ratio II (RII). Five heathy persons walked on the treadmill wearing AiKneeOne at speeds of 0.5, 0.7, 1.1 m/s, and the indice were collected with the wearable gait collect system. ResultsUnder different velocities, The absolute value of SI and RII were very little and the RI were close to one at the phases of the first double-limb support and the second double-limb support, but they were not very satisfactory in the phases of the single-limb support and the swing. ConclusionThe developed MPK AiKneeOne is potential to reconstruct the gait of amputees, and the gait symmetry indice can be used to evaluate the wearing performance of MPK.

Differences of temporomandibular joint symmetry in patients with unilateral complete cleft lip and palate at different developmental stages / 中南大学学报(医学版)

OBJECTIVES@#Currently, the research results regarding the bilateral temporomandibular joint symmetry in patients at different ages with unilateral complete cleft lip and palate (UCLP) are still controversial. In this study, the position of condyle in the articular fossa and morphology of condyle in UCLP patients at different developmental stages was measured and analyzed to explore the asymmetry difference, which can provide a new theoretical basis for the sequential therapy.@*METHODS@#A total of 90 patients with UCLP were divided into a mixed dentition group (31 cases), a young permanent dentition group (31 cases) and an old permanent dentition group (28 cases) according to age and dentition development. Cone beam computed tomography (CBCT) images were imported into Invivo5 software for 3D reconstruction, and the joint space, anteroposterior diameter, medio-lateral diameter, and height of condylar were measured, and its asymmetry index was calculated.@*RESULTS@#The asymmetry index of condylar height and anteroposterior diameter among the 3 groups, from small to large, was the mixed dentition group<the young permanent dentition group<the old permanent dentition group (both P<0.05). There was no significant difference in condylar anteroposterior diameter and asymmetry index between the mixed dentition group and the young permanent dentition group (both P>0.05), all of them were lower than those in the old permanent dentition group (both P<0.05). Compared with the normal side, the height of fracture condyle was smaller among the 3 groups (all P<0.05), and the anterior joint space was smaller (P<0.05) and the posterior joint space was larger (P<0.05) in the mixed dentition group.@*CONCLUSIONS@#In patients with UCLP, the asymmetry of condylar morphology increases with age, but the condylar position tends to normal. These results suggest that early treatment has important clinical significance for the morphologic development of temporomandibular joint in UCLP patients.

Application of three-dimensional scanning technology in evaluating breast symmetry in reduction mammaplasty / 中华医学美学美容杂志

Objective:To evaluate the aesthetic results of bilateral breast symmetry after reduction mammaplasty, we proposed a handheld 3D scanner-based evaluation method to achieve the desired aesthetic effects.Methods:From June 2018 to June 2019, a total of 56 female patients with an average age of 34 years (18 to 56 years) requested for bilateral breast reduction in the Department of Aesthetic and Reconstructive Breast Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Three-dimensional scans were performed intraoperatively in 27 cases in study group, and symmetry adjustments were made during breast contouring based on the analysis results; in the control group, a total of 29 patients did not undergo three-dimensional scans intraoperatively. Three-dimensional scans were obtained from both groups 3 months after surgery to objectively assess breast symmetry. Six third-party physicians scored the two groups based on anonymous photographs of the patients in 5 dimensions of breast symmetry to assess the symmetry of the pre- and post-operative bilateral breasts.Results:The difference in breast volume in the study group was significantly smaller bilaterally than in the control group [35.26 (20.01, 55.61) vs 110.02 (43.52, 186.30) cm 3,U=221.00, P=0.001]. The results reported by the evaluators showed that all five aspects of breast symmetry measured by breast reduction were significantly improved in the study group compared to the preoperative period ( P<0.001) and were all statistically superior to the control group ( P<0.05). Conclusions:Intraoperative three-dimensional scanning technology presents a dependable method to facilitate in optimizing bilateral breast symmetry, which in turn provides an opportunity to enhance the aesthetic outcome after reduction mammoplasty.

Predictive index based on minimum corneal thickness and symmetry index back of Sirius for early diagnosis of keratoconus / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: To construct and validate a diagnostic model for early detection of keratoconus based on parameters in Sirius.METHODS: The study comprised of 46 early keratoconus eyes(including 20 right eyes and 26 left eyes in 34 patients)and 46 age- and gender-matched normal eyes(including the right eyes of 46 patients)in the prediction group. The predictive index was constructed using LASSO and Logistic regression analyses based on the topographic, pachymetric and aberrometry variables of Sirius. There were 23 early keratoconus eyes categorized as suspected keratoconus cases by Sirius(including 12 right eyes and 11 left eyes in 23 patients)and 23 age- and gender-matched normal eyes(including the right eyes of 23 patients)included in the application cohort. External validation of predictors was performed for the application cohort.RESULTS: Sirius Keratoconus Index(SKI)was calculated based on the minimum corneal thickness and symmetry index back of Sirius. Highest AUC values were obtained in the prediction group(AUC=0.932)after Logistic regression analysis. The cut-off value of SKI was set at 0.44. Then, the receiver operating characteristic(ROC)curve, calibration plot and nomogram of the diagnostic formula were analyzed for the prediction cohort in detail. Finally, the accuracy of the SKI was evaluated in the application cohort; the sensitivity was 91% and the specificity was 96%.CONCLUSION: SKI based on minimum corneal thickness and symmetry index back of Sirius is a simple and effective method for early detection of keratoconus in the preoperative screening for refractive surgery.

Correlation between gait parameters and balance in stroke hemiplegic patients / 中国康复理论与实践

@#Objective To investigate the relationship between gait spatiotemporal parameters and balance function in stroke hemiplegic patients. Methods From September, 2018 to March, 2020, 76 stroke hemiplegic patients (38 in Brunnstrom Ⅳ and V, respectively) were assessed balance function with Active Balancer EAB-100 and Star Excursion Balance Test (SEBT), and gait parameters of speed, cadence and asymmetry, named step length asymmetry ratio (SLA), swing time asymmetry ratio (SWTA), stance time asymmetry ratio (STA), maximum flexion angle ratio (MFA) of hip and knee. The correlation among gait parameters and balance function was analysed. Results The balance and gait parameters were better in those in Brunnstrom V than in Brunnstrom Ⅳ (|t| > 2.268, P < 0.05). The speed and cadence correlated with the most balance indexes (|r| > 0.335, P < 0.05). SLA correlated with SEBT in Brunnstrom Ⅳ patients (r = -0.467~-0.613, P < 0.01), while it correlated with medial-lateral (M-L) stability limits in Brunnstrom V patients (r = -0.356, P = 0.028). SWTA correlated with stability limit of Anterior-Posterior (A-P) (r = -0.335, P = 0.040) and M-L (r = 0.510, P = 0.001), and most of SEBT (r = -0.330~ -0.445, P < 0.05) in Brunnstrom Ⅳ patients. MFA of hip and knee correlated with balance indexes in Brunnstrom Ⅳ patients (|r| > 0.326, P < 0.05), while MFA of knee correlated with most balance indexes in Brunnstrom V patients (r > 0.329, P < 0.05), and MFA of hip correlated with A-P stability limit (r = 0.369, P = 0.023). Conclusion Both speed and cadence of steps can well respond to the balance function in stroke hemiplegic patients. For the asymmetry, it is related with balance in patients with poorer recovery.

Bilaterality and symmetry of c-shaped mandibular second molars in a Mexican Maya and non-Maya population: a CBCT in vivo study / Bilateralidad y simetría de los segundos molares mandibulares en forma de c en una población mexicana Maya y no Maya: estudio in vivo mediante CBCT

SUMMARY: The objective of this study was to evaluate the bilaterality and symmetry in C-shaped mandibular second molars in Mexican Maya and non-Maya populations using cone-beam computed tomography (CBCT). Five-hundred-twenty-five CBCT scans of patients with left and right mandibular second molars were analyzed to determine the prevalence and bilaterality. The teeth were assessed for the presence of C-shaped root canals, according to Fan et al. (2004) criteria. The sample was subdivided by ethnicity, sex, unilateral/bilateral presence, side of the longitudinal groove, and the C-shaped root canal configuration and symmetry, at the cervical, middle, and apical cross- sections of the root. C-shaped mandibular second molars were present in 24.95% of the individuals. Most (60.30%) of those showing this trait had it bilaterally. When comparing by ethnicity, sex, and side, we detected no significant differences. The vast majority (97.33%) presented the groove along the lingual side. The C3 was the most prevalent configuration in the overall sample, while in the Maya group, the C1 was the most common configuration. When analyzed by sex and ethnic group, the non-Maya females tended to deviate from the other groups in terms of bilaterality. Overall, 55.70% of bilateral C-shaped mandibular second molars were also symmetric in the three radicular thirds. The prevalence of C-shaped mandibular second molars was similar to that reported for northernAsian populations, which is consistent with the evolutionary origins of Native American populations. Most of the sample showed bilaterality and half were symmetric. Clinicians must be aware of the ethnic background of their patients and consider the possible variations to do more predictable root canal treatments.

RESUMEN: El objetivo de este estudio fue evaluar la bilateralidad y simetría de los segundos molares mandibulares en forma de C en una población Mexicana Maya y no-Maya mediante tomografía computarizada de haz cónico (CBCT). Material and Métodos: Se analizaron quinientos veinticinco tomografías de pacientes con segundos molares mandibularesderecho e izquierdo para determinar la prevalencia y bilateralidad. Los dientes fueron evaluados según la presencia de conductos en forma de C de acuerdo a los criterios de Fan et al. La muestra fue subdividida por etnicidad, sexo, presencia bilateral/unilateral, lado del surco y configuración y simetría de los conductos en los cortes transversales cervical, medio y apical. Los segundos molares mandibulares en forma de C estuvieron presentes en el 24.95 % de los individuos. La mayoría (60.30%) de los que mostraron este rasgo lo hicieron de forma bilateral. El comparar por etnicidad, sexo y lado, no se encontraron diferencias estadísticamente significativas. La gran mayoría (97.33%) presentó el surco por lingual. C3 fue la configuración más prevalente en la muestra general, mientras que en el grupo Maya el C1 fue la más común. El análisis por sexo y grupo étnico arrojó que las mujeres no Mayas tendieron a desviarse de los otros grupos en términos de bilateralidad. El 55.70% de los segundos molares mandibulares bilaterales fueron simétricos en sus tres tercios radiculares. La prevalencia de los segundos molars mandibulares en forma de C fue similar a la reportada para las poblaciones del norte de Asia, lo cual es consistente con los orígenes evolutivos de las poblaciones nativas americanas. La mayor parte de la muestra presentó el rasgo de forma bilateral y la mitad de éstos fueron simétricos. Los odontólogos deben tomar en cuenta el origen étnico de sus pacientes y considerar las posibles variaciones para realizar tratamientos endodónticos más predecibles.

CBCT study of the root and root canal morphology of mandibular second molars in a population in western Guangxi / 口腔疾病防治

Objective@#To observe the root and root canal morphology of mandibular second molars in Western Guangxi by CBCT, to provide a reference for clinical diagnosis and treatment.@*Methods@#In total, 564 patients′ 1 128 mandibular second molars that satisfy the inclusion criteria were analyzed with a planmecaromexis CBCT machine and its own image analysis software. The patients′ gender, age and ethnic differences in the root and canal morphology and the symmetry of the bilateral root and canal were statistically analyzed. @*Results@# Among the 1 128 mandibular second molars, 662 were the Zhuang ethnic group and 384 were the Han ethnic group, and 82 were other ethnic groups; the double root type and C-shaped root type accounted for a relatively high proportion: 73.94% and 24.47%, respectively. The detection rates of the double root type were higher in males than in females (P < 0.05); the detection rates of the C-shaped root type were higher in females than in males (P <0.05); the root type of the teeth was mainly double-rooted in the Zhuang ethnic group (P<0.01). The incidence of type IV in the mesial root of the double root type mandibular second molar was the highest (P < 0.01), and the incidence of type I in the distal root was the highest (P < 0.01). The C-shaped root canal is more continuous at the mouth of the root canal, more downward corresponds to a worse continuity: in three different levels of root canal orifice, root middle and root apex, the root canal orifice is dominated by the C1 type, and both root middle and root apex are mainly C3-type (P < 0.01). The difference in symmetry of bilateral roots and root canals was statistically significant among different gender groups, age groups, and ethnic groups (P < 0.05): there were more males than females, the results in the 18-35-year-old group and the Zhuang ethnic group were higher.@*Conclusion@# The root and root canal morphology of mandibular second molars in western Guangxi people are complex and changeable. The roots are mainly double root type in the Han ethnic group and the Zhuang ethnic group. C-shaped roots are also common. The detection rate of C-shaped roots in the Zhuang ethnic group was higher, and the symmetry rate of bilateral roots and that of bilateral root canals was higher in the Zhuang ethnic group than in the Han ethnic group.

Static Balance Function in Stroke Patients: A Plantar Pressure Analysis / 中国康复理论与实践

Objective:To explore the mechanism of balance control after stroke by plantar pressure analysis. Methods:From July to December, 2019, twelve stroke subjects (stroke group) and 30 normal subjects (control group) were recruited in the rehabilitation department of our hospital. Both groups were measured plantar pressure in eyes open and closed conditions. The kinematic parameters, dynamic parameters, plantar pressure center (CoP), symmetry index (SI), symmetry angle (SA) and Romberg quotient (RQ) were calculated. Results:Compared with eyes open condition, the average Y and maximum swing of the control group increased significantly in eyes closed condition (P < 0.01); moreover, the ball length, average speed and maximum swing increased significantly in the stroke group (P <0.05). Compared with the control group, the area of the ellipse (|t| > 3.509, P < 0.001) and the average X (|Z|> 2.311, P < 0.05) significantly increased both in eyes open and closed condition, whereas the maximum swing (Z = -3.118, P < 0.01) increased significantly in eyes closed condition in the stroke group. The RQ of ball length was significantly more in the stroke group than in the control group (t = -3.570, P < 0.01). There was no significant difference in SI and SA of all parameters between the eyes open and closed condition in two groups (P > 0.05). Compared with the control group, load SI, overall load SI, forefoot load SI, area SI and forefoot area SI increased in both the eyes open and closed conditions in the stroke group (t > 2.344, P < 0.05), whereas load SA, overall load SA, forefoot load SA, area SA, forefoot area SA increased (|t|> 2.297, P < 0.05), hindfoot load SA increased only in eyes open condition (t = -2.485, P < 0.05), and hindfoot area SA increased only in eyes closed condition (t = -2.132, P < 0.05). In the control group, CoP was mainly distributed in the negative direction of Y axis when the eyes were open and closed, while CoP in the stroke group was relatively discrete, and the distribution on X axis was more obvious than that of the control group. Conclusion:The balance control of stroke patients might depend on visual compensation, and the plantar pressure analysis system could be used to evaluate the balance function in stroke patients.

Analysis of Ground Reaction Forces during Running Based on One-Dimensional Statistical Parametric Mapping / 医用生物力学

Objective To analyze the difference in ground reaction force (GRF) between male and female runners and between left and right limbs using the one-dimensional statistical parametric mapping (SPM). Methods Thirty male and female runners participated the running test on force treadmill at the speed of 12 km/h. GRF of consecutive five steps were recorded. The independent-sample t test and paired-sample t test in the SPM package were used to check the male vs female and right limb vs left limb differences. Results Male and female runners showed inter-limb asymmetry in vertical average loading rate (VALR), and the VALR of male runners was significantly higher than that of female runners in the left limb, while no significant differences were found in the right limb. Male and female runners showed significant differences in the right vertical GRF during push-off and medial-lateral GRF during landing, while left medial-lateral GRF presented significant differences during landing and mid stance. Male runners showed right limb vs left limb significance in the anterior-posterior GRF during push-off, vertical GRF during landing and push-off and medial-lateral GRF during landing, while female runners exhibited right limb vs left limb significance in vertical GRF during landing and push-off. Conclusions This study introduced the application of SPM in statistical analysis of GRF, elaborated the procedures and theory, compared the test of time-series data in SPM and discrete value with traditional statistics, and discussed the difference and features in SPM and SnPM, thus providing references for the application in data analysis of sports biomechanics. Comparison in the male vs female and right limb vs left limb revealed the genders and inter-limb symmetrical differences in the landing, mid-stance and push-off phases during stance. The research findings laid the foundation for future investigation of mechanism in running related injuries and strategy of prevention and treatment.

Effect of immediate prosthetic breast reconstruction in patients with breast cancer / 中华医学美学美容杂志

Objective:To explore and analyze the influence of thoracic types and symmetry methods on the treatment effect before operation for the breast cancer patients undergoing immediate breast reconstruction.Methods:From January to October 2018, 30 female patients with unilateral breast cancer, aged 33-48 (39.6±4.6) years, were treated in the Breast Center of Qingdao University Affiliated Hospital. Thoracic CT was used to analyze thoracic types and symmetry. The measurement indexes included the maximum transverse diameter of thorax, the maximum longitudinal diameter of left and right sides, the ratio of the maximum transverse longitudinal diameter of left and right sides, the anterior chest angle of left and right sides, the posterior chest angle and the external chest angle, and the type and symmetry of thorax were analyzed, and the choice of prosthesis was adjusted according to the measurement results.Results:All the 30 patients recovered smoothly, and no complications such as infection and prosthesis removal occurred. Anatomical prostheses were selected in 22 patients, including 12 cases with medium high protrusion prosthesis, 10 cases with low protrusion prosthesis and 8 cases with round low protrusion prosthesis. The average follow-up time was 15 months after operation. The postoperative follow-up photos were evaluated aesthetically by using the BRAST-Q questionnaire and 3 non-operative doctors, among which 22 cases were excellent, 4 cases were good, 3 cases passed and 1 case was poor. Excellent and good rate was 86.7%. Among them, 3 cases were satisfactory, 1 case was scar hyperplasia of local incision, 2 cases were mild capsular contracture, and 1 case was subject to prosthesis displacement.Conclusions:The measurement and analysis of thoracic type and symmetry before operation can help to adjust the choice of prosthesis, check the obvious thoracic deformity and avoid affecting the surgical results.

Pharmacovigilance of traditional Chinese medicine: an exploration based on prescription sequence analysis and prescription sequence symmetry analysis / 中国中药杂志

Multiple methods should be incorporated into the research on pharmacovigilance of traditional Chinese medicine(TCM for a comprehensive and objective evaluation. The arrival of the era of medical big data allows it to be deeply integrated into medical research. The real world study(RWS) represented by hospital information system(HIS) provides a data basis for exploring the pharmacovigilance of TCM. Prescription sequence analysis(PSA) and prescription sequence symmetry analysis(PSSA) developed based on the former serve as a methodological basis for clinical safety evaluation of Chinese patent medicines after marketing. By collating the related studies of HIS, PSA and PSSA and employing the propensity score matching( PSM) method and nested case-control study(NCCS), this paper formed a HIS-, PSA-and PSSA-based technical system for clinical safety evaluation of Chinese patent medicines in the real world, in order to provide a methodological demonstration for the future research on the pharmacovigilance of TCM.

Reconstrucción mamaria inmediata en el Instituto Nacional de Oncología y Radiobiología de Cuba / Immediate Breast Reconstruction at the National Institute of Oncology and Radiobiology of Cuba

RESUMEN Introducción: La reconstrucción mamaria inmediata disminuye el impacto psicológico del cáncer de mama y mejora la calidad de vida de las pacientes. Objetivo: Evaluar la simetría en la reconstrucción mamaria inmediata en el Instituto Nacional de Oncología y Radiobiología de Cuba. Método: Se realizó un estudio analítico y prospectivo, de cohorte incidente, en el Servicio de Cirugía Reconstructiva del Instituto Nacional de Oncología y Radiobiología de 2014 al 2017. Se incluyeron 41 pacientes que consintieron participar en el estudio. Se recogieron variables demográficas y onco-reconstructivas. Se utilizó un software creado en la institución para evaluar la simetría mamaria. Los datos se recogieron de la historia clínica. Se aplicaron el test de Chi-cuadrado corregido y la razón de momios para el análisis estadístico. Resultados: El 30,2 por ciento de mujeres reconstruidas pertenecieron al grupo de 30 a 39 años; el 46,3 por ciento tenían sobrepeso. La mejor simetría se encontró con las técnicas oncoplásticas (31,7 por ciento), seguida de la mastectomía ahorradora de piel. La técnica de expansión tisular con la mastectomía presentó mayores complicaciones (63,6 por ciento) y menor simetría. La necrosis parcial de piel fue la mayor complicación en 7,3 por ciento y estuvo relacionadas con las técnicas ahorradoras de piel. Conclusiones: Evaluar de forma objetiva la simetría mamaria permitió conocer la efectividad de las técnicas quirúrgicas reconstructivas. Con las técnicas de cirugía oncoplástica y mastectomía ahorradora de piel se obtuvieron los mejores resultados estéticos y pocas complicaciones. La expansión mamaria inmediata con una mastectomía radical modificada no ofrece ninguna ventaja(AU)

ABSTRACT Introduction: Immediate breast reconstruction reduces the psychological impact of breast cancer and improves the quality of life of patients. Objective: To assess symmetry in immediate breast reconstruction at the of Cuba. Method: An analytical and prospective study of incident cohort was carried out in the reconstructive surgery service at the National Institute of Oncology and Radiobiology (INOR), from 2014 to 2017. Forty-one patients who consented to participate in the study were included. Demographic and oncoreconstructive variables were collected. A software created in the institution was used to assess breast symmetry. The data were collected from the medical histories. The corrected chi-square test and odds ratio were applied for statistical analysis. Results: 30.2 percent of women who received reconstruction belonged to the age group 30-39 years; 46.3 percent were overweight. The best symmetry was found with oncoplastic techniques (31.7 percent), followed by skin-sparing mastectomy. The tissue expansion technique with mastectomy presented greater complications (63.6 percent) and less symmetry. Partial skin necrosis was the major complication, accounting for 7.3 percent of the cases, and was related to skin-sparing techniques. Conclusions: Objectively evaluating breast symmetry allowed us to know the effectiveness of reconstructive surgical techniques. With oncoplastic surgery and skin-sparing mastectomy techniques, the best aesthetic outcomes and few complications were obtained. Immediate breast expansion with a modified radical mastectomy offers no benefit(AU)

Modalidades de razonamiento en díadas durante la resolución de problemas lógicos / Modalities of reasoning in dyads during problem solving

Resumen Objetivos: a) Identificar cualitativamente modalidades de razonamiento en díadas que resuelven problemas lógicos; b) explorar si estas varían en función de tres tipos de composición diádica: dos compañeros de baja competencia (simetría baja), dos compañeros de alta competencia (simetría alta) y un compañero de baja competencia junto a otro de alta competencia (asimetría). Método: Participaron 36 díadas (72 sujetos, edad: M=11 años, 3 meses; DE= 7 meses), de alumnos de quinto y sexto grado de primaria de Rosario (Argentina) La tarea consistió en una serie de diez ítems lógicos de dificultad creciente (matrices progresivas). Esta fue realizada de dos maneras: primero, de modo individual; segundo, bajo una modalidad colaborativa (en díada). El análisis de contenido se concentró en ítems seleccionados intencionalmente y estuvo basado en la construcción recursiva de categorías (método comparativo constante). Resultados: El análisis de las interacciones permitió identificar seis modalidades básicas de razonamiento, que fueron desde un nivel inicial basado en una selección arbitraria de la respuesta, hasta un nivel de alta complejidad basado en la construcción de sentido lógico integrando filas y columnas. Por otra parte, las modalidades más rudimentarias (ensayo-error) predominaron en las díadas con simetría baja (40,0%), mientras que las más avanzadas (de construcción de sentido entre filas y/o columnas) así lo hicieron en las díadas asimétricas (47,4%). Conclusiones: Los resultados permiten ahondar en la comprensión de los procesos sociocognitivos entre pares, especialmente en relación a los fundamentos lógicos propuestos en la actividad. Al mismo tiempo, se discute el concepto de modalidad de razonamiento y se lo diferencia del concepto de modalidad sociocognitiva.

Abstract Objetives: (a) To identify qualitatively modalities of reasoning in dyads that solve logical problems; b) to explore if they vary depending on three types of dyadic composition: two low-competence partners (low-competence symmetry), two high-competence (high-competence symmetry); a low-competence subject with a high-competence subject (asymmetry). Method: Participants were 36 dyads (72 subjects, age: M=11 years old, 3 months; SD= 7 months) of 5th and 6th grade of elementary school, from Rosario (Argentina). The task consisted of a series of ten logical items of increasing difficulty (progressive matrices). This was performed in two ways: first, individually; then, collaborative modality (dyad). The content analysis was concentrated on intentionally selected items and was based on the recursive construction of categories (constant comparative method). Results: The analysis of interactions allowed identifying six basic modes of reasoning, that were from an initial level based on an arbitrary selection of the answer, up to a level of high complexity based on logical sense construction integrating rows and columns. Moreover, the most rudimentary modalities (trial and error) predominated in the low-competence symmetry dyads (40.0%), while the most advanced (construction of sense between rows and/or columns) predominated in the asymmetric dyads (47.4%). Conclusions: The results allow to depth in the understanding of peer socio-cognitive processes, especially in relation to the logical fundaments proposed in the activity. At the same time, the concept of modality of reasoning is discussed and it is differentiated from the concept of socio-cognitive modality.

Effects of Electro-Acupuncture on Vertical Ground Reaction Force and Impulse Symmetry of Patients with Knee Osteoarthritis during Stair Climbing / 医用生物力学

Objective To observe the effects of electro-acupuncture on loading of lower limb joints in patients with knee osteoarthritis (KOA) during stair climbing and explore the related biomechanical mechanism. Methods Forty patients with KOA were randomly assigned, with 20 patients in observation group (electro-acupuncture group, EA group) and 20 patients in control group (superficial acupuncture group, SA group). Finally 18 patients in each group completed the study. In observation group, seven knee acupuncture points were chosen and patients were connected with electro-acupuncture instrument; while in control group, the electro-acupuncture instrument was connected but not electrified after superficial acupuncture at non-acupoint points. The three-dimensional gait analysis system was used to assess the biomechanical characteristics during stair climbing before and after treatment, including peak vertical force (PFz), vertical impulse (IFz) and symmetry index (SI%). Results After 3 weeks of treatment in EA group, PFz of the right foot during stair ascent and PFz of the left foot during stair descent increased (P＜0.05); IFz of both feet during stair ascent and IFz of the right foot during stairs descent significantly decreased (P＜0.05); no significant differences were found in SI% of peak and impulse (P＞0.05). In SA group, only SI of impulse during stairs ascent increased (P＜0.05). There was no significant difference between two groups before and after treatment (P＞0.05). Conclusions Electro-acupuncture can effectively improve the joint load capacity and reduce the dynamic cumulative load of patients w

Clinical study of concealed penis correction surgery based on principle of midline symmetry / 中国修复重建外科杂志

Objective: To investigate the effectiveness of concealed penis correction surgery based on the principle of midline symmetry. Methods: Between January 2016 and September 2018, 18 children with concealed penis were treated with correction surgery based on the principle of midline symmetry. All children were 3-12 years old, with an average age of 8.3 years. Physical examination showed that the penis was short; the penis body could not be exposed or be exposed too limited; the corpus cavernosum developed well. The pressure dressing was removed at 3 days after operation and the urethral tube was removed. The color of the glans, the swelling and congestion of penis and scrotum, and the blood supple of the prepuce flap were observed. Results: The operation time ranged from 47 to 54 minutes, with an average of 50 minutes. All children were followed up 3 months after operation. There was no hemorrhage and necrosis of the glans and no infection or ischemic necrosis of the flap. All patients had different degree of prepuce edema at 3 days after operation, 5 patients still had prepuce edema at 2 weeks, and the prepuce edema in all patients subsided at 3 months. All penises were exposed well after midline symmetric anastomosis with no bulky prepuce and scrotum. Conclusion: The correction surgery based on the principle of midline symmetry can be used to correct the appearance of the concealed penis effectively.

Analysis of gait and effectiveness after unicompartmental knee arthroplasty / 中国修复重建外科杂志

Objective: To explore the gait trajectory characteristics and effectiveness after unicompartmental knee arthroplasty (UKA). Methods: Thirty patients (30 knees) with anterior medial compartment osteoarthritis who were treated with UKA between January 2017 and December 2018 were selected as subjects (UKA group). According to age, gender, and side, 30 patients (30 knees) with knee osteoarthritis treated with total knee arthroplasty (TKA) were selected as control (TKA group). In addition to the range of motion (ROM) before operation showing significant difference between the two groups ( t=4.25, P=0.00), there was no significant difference in gender, age, disease duration, sides, body mass index, and preoperative hip-knee-ankle angle (HKA), Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score between the two groups ( P>0.05). The incision length, drainage volume within 24 hours after operation, and the changes of hemoglobin and albumin were recorded. The WOMAC score, ROM, and HKA before and after operation were compared between the two groups. At 1 year after operation, the gait trajectory characteristics of two groups were analyzed by Vicon three-dimensional gait capture system, and the absolute symmetry index (ASI) of the lower limbs of the two groups was calculated. Results: The incisions of the two groups healed by first intention, with no complications. The incision length, drainage volume within 24 hours, and the changes of hemoglobin and albumin after operation in the UKA group were significantly smaller than those in the control group ( P0.05). The ASI of bilateral knee flexion in the UKA group was significantly greater than that in the TKA group during the initial contact and loading response period ( P<0.05). Conclusion: Compared with TKA, UKA has the advantages of small incision, less blood loss, and quicker functional recovery. The early gait after UKA is mainly manifested as the increase in walking speed, stride length, knee flexion at swing, and extension at mid-stance phase. From the analysis of gait symmetry, during the initial contact and loading response phase, the operation side after UKA undertakes more shock absorption and joint stabilization functions than the contralateral side.

Dominant and non-dominant side knee isokinetic characteristics of Chinese calisthenics athletes / 中国组织工程研究

BACKGROUND: A comprehensive evaluation of knee muscle strength, knee hamstrings-to-quadriceps (H/Q) force ratio, and symmetry of both knee joints is beneficial to preventing knee joint injuries. OBJECTIVE: To analyze the dominant and non-dominant side isokinetic characteristics of the knee joints of Chinese calisthenics athletes and bilateral symmetry of muscle strength. METHODS: Knee joints of 22 Chinese calisthenics athletes (aerobics group, n=8; athletics group, n=14) from Chinese national aerobics team were measured using IsoMed2000 at 60 and 180 (°)/s concentric angular speed. RESULTS AND CONCLUSION: The peak torque (PT) and the relative peak torque (PT/BW) of the flexors and extensors of the knee joint in the two groups were significantly decreased with the increase of the angular speed (P < 0.001), and the H/Q ratio significantly increased with the increase of the angular speed (P < 0.001). The dominant leg flexors strength were significantly higher than that of the non-dominant leg (P < 0.05), and extensors strength and H/Q of the dominant leg were significantly higher than those of the non-dominant leg at the speed of 60 (°)/s (P < 0.05). The H/Q of the non-dominant knee joint in the aerobic group was significantly higher than that in the athletics group at the speed of 180 (°)/s (P < 0.05). In the aerobic group, the flexor peak torque of the dominant leg was significantly higher than that of the non-dominant leg at the speed of 60 (°)/s and 180 (°)/s (P < 0.05), but there was no significant difference in both side of extensors. In the athletics group, the flexor peak torque of the dominant leg was significantly higher than that of the non-dominant leg (P < 0.05), the extensors peak torque [60 (°)/s], PT/BW [60 (°)/s] and H/Q [180 (°)/s] of the dominant leg were significantly higher than those of the non-dominant leg (P < 0.05). These findings indicate that the muscle force of the dominant and non-dominant knee joints were asymmetric, and the athletes ought to improve the muscle power of the non-dominant knee joint. A lower H/Q indicates imbalance between the flexor and extensor strength of the knee joint, and it is necessary to strengthen the knee flexor strength training, especially the training for fast strength.