Age Determination From Macroscopic Examination Of Sphenooccipital Synchondrosis Closure.

Abstracts: Background & Objective: Age determination from degree of closure of sphenooccipital suture (Synchondrosis). Methodology: This study was conducted during the period of January 2012 to August 2013 at Department of Forensic Medicine, P.D.U. Govt. Medical College & Hospital, Rajkot. 100 cases of age between 8 to 26 years have been taken to cover minimum period of starting the fusion and maximum period of completion of fusion for age determination from sphenooccipital suture. Results: For male, minimum age for open, semi closed and closed sphenooccipital suture was 8 years, 13 years and 18 years respectively while for female, it was 8 years, 13 years and 16 years respectively. For male, maximum age for open, semi open and closed sphenooccipital suture was 13 years, 18 years and 26 years respectively while for female, it was 13 years, 16 years and 26 years respectively. Conclusion: Commencement of union at sphenooccipital suture occurs at the age of 13 years in both sex and complete obliteration of cartilaginous disc occurs at the age of 18 years in male and 16 years in female.

Age Determination From Macroscopic Examination Of Sphenooccipital Synchondrosis Closure.

Abstracts: Background & Objective: Age determination from degree of closure of sphenooccipital suture (Synchondrosis). Methodology: This study was conducted during the period of January 2012 to August 2013 at Department of Forensic Medicine, P.D.U. Govt. Medical College & Hospital, Rajkot. 100 cases of age between 8 to 26 years have been taken to cover minimum period of starting the fusion and maximum period of completion of fusion for age determination from sphenooccipital suture. Results: For male, minimum age for open, semi closed and closed sphenooccipital suture was 8 years, 13 years and 18 years respectively while for female, it was 8 years, 13 years and 16 years respectively. For male, maximum age for open, semi open and closed sphenooccipital suture was 13 years, 18 years and 26 years respectively while for female, it was 13 years, 16 years and 26 years respectively. Conclusion: Commencement of union at sphenooccipital suture occurs at the age of 13 years in both sex and complete obliteration of cartilaginous disc occurs at the age of 18 years in male and 16 years in female.

Odontoid Synchondrosis Fracture Treated by C1-2 Polyaxial Screw-Rod Fixation

The synchondrosis between the dens and the body of axis normally fuses between 5 and 7 years of age. Until this age, synchondrosis fractures can occur in children. Most synchondrosis fractures are conventionally treated by external immobilization alone. We report a 10-year-old child with odontoid synchondrosis fracture who was treated by C1 lateral mass and C2 pars screw rod fixation with a successful outcome and discuss the possible reasons for occurrence of odontoid synchondrosis fracture in this older child as well as the indications for surgery in this condition.

The Role of Microtubule in the Regulation of Endochondral Bone Formation in the Developing Mouse Cranial Base / 체질인류학회지

Endochondral bone formation of the developing cranial base is a complex process. This mechanism requires precise orchestration of many cellular events and cartilage matrix metabolism, such as proliferation, becoming round in shape, termination of proliferation, hypertrophic size-increase, and finally programmed cell death. Active formation and degradation of cartilage matrix take place, in which microtubules are involved for intracellular events; bone apposition follows these events. However, the involvement of microtubules during these changes in the developing cranial base has not been identified yet. Thus, we investigated the involvement of microtubules in the regulation of endochondral bone formation during cranial base development. Using tubulin-binding drug nocodazole, we examined the effects of altering the structure and function of microtubules during in vivo organ culture of the mouse cranial base. Cultured specimens were analyzed with HE staining, immunohistochemistry, and cell counting in order to study the morphological and molecular changes that occurred in the tissues. Disruption of the microtubular array by nocodazole reduced cells expressing proliferation marker Ki67, osteogenic marker BSP, and BMP4 within the sphenooccipital synchondrosis region; chondrocyte hypertrophy was ceased in the hypertrophic zone; degeneration of cartilage matrix and bone matrix apposition was inhibited in the ossification center of the basooccipital cranial base. Our data demonstrated that disruption of microtubules by nocodazole have multiple inhibitory effects on the sequential changes that occur during endochondral bone formation, suggesting the importance of normal microtubule-polymerization in cranial base development.

HRCT Study of the Sphenooccipital Synchondrosis / 实用放射学杂志

Objective To evaluate the development of the sphenooccipital synchondrosis on high resolution CT scans.Methods 269 cases,HRCT findings of the sphenoocipital synchondrosis ranged in age from 3 months to 74 years old were analysed.Four points were assessed on HRCT scans (a) The pattern of the synchondrosis, (b) The location and time of appearance of the ossification center in the synchondrosis, (c) The vestige of the synchondrosis after fusion of the sphenoid and occipital bones and (d) The development of sphenoid sinus.Results The pattern of the sphenooccipital synchondrosis could be classified into three types, including complete opening, partial and complete closure. The spheno-occipital synchondrosis was variable in shapes in opening group,a notch existed in 57 cases, the mean of the thickness of the spheno-occipital synchondrosis was 1.8 mm, there was negative correlation between the thickness of the synchondrosis and the age (r= -0.92,P

The relationship between the growth of cranial base and the position of maxilla, mandible in complete unilateral cleft lip and palate patients / 대한치과교정학회지

This study was designed to evaluate the correlations between the morphology and growth of cranial base and the position of nasomaxillary complex and mandible in complete unilateral cleft lip and palate patients. Craniofacial skeletal morphology pattern was analyzed on the lateral cephalometric radiographs of the 100 subjects of complete unilateral cleft lip and palate group and the 100 normal grower group and each group was divided three sub-groups by age-range like spheno-ethmoidal synchodrosis growing group, spheno-occipital synchondrosis growing group and finished synchondrosis growth group. These data were statistically analyzed to examine significant difference between both groups and between each sub-groups. The results of this study were as follows: 1. In complete unilateral cleft group, the length, thickness of clivus, and the rate of increase in length of clivus showed smaller amount by adolescence. The anterior length of cranial base and the rotation pattern of clivus with age showed no significant difference between two group. 2. In complete unilateral cleft group, nasomaxillary complex were located more posteriorly. This difference between two groups is larger by adolescent group than adult. Vertical position showed no significant difference between two gi oups. There was significant correlation between the cranial base of cleft group and the horizontal measurements(p<0.01). PtmS showed no significant increment in cleft group. This showed the deficiency of growth in posterior part of maxilla. . 3. In mandible, there was no significant difference between normal group and complete unilateral cleft group but articular angle showed significantly smaller in cleft group than in normal one. And the measurements of nasomaxillary complex position, cranial base and the position of mandible had significant correlation(p<0.01).

A Case of Chondroma in Middle Cranial Fossa: Case Report

Intracranial chondromas are extremely rare tumors, but when present, are generally related to the synchondrosis of the base, and they have several distinct features. They are slow growing benign tumors, and plain roentgenogram frequently reveals lytic lesion and stippled calcification at base of the skull. They are radioresistant, and surgical removal is treatment of choice. We report the rare case of chondroma arisen from base of the skull which diagnosed by brain CT and confirmed by operation.