ABSTRACT
Objective To observe the effect of the method of warming kidney and dredging collaterals on the clinical effect and the content of urine C5b-9 in patients with idiopathic membranous nephropathy with spleen kidney yang deficiency and blood stasis. Methods A total of 60 idiopathic membranous nephropathy patients with spleen kidney yang deficiency and blood stasis type were randomly divided into the conventional western medicine treatment group (control group), Jingui-Shenqi pill and Taohong-Siwu decoction plus conventional western medicine treatment group (treatment group), 30 cases in each group. The Scr was detected by deproteinized alkaline picric acid method, and BUN was detected by rate method, and serum albumin (ALb) was detected by bromocresol green dye binding method, and 24 hours urinary protein was measured by pyrogallol red colorimetry, and the double antibody sandwich ELISA method was used for detection of urinary C5b-9. Results The Jingui-Shenqi pill combined with Taohong-Siwu decoction plus conventional western medicine treatment has obvious curative effect on patients. The total effective rate was 83.3 in the treatment group (25/30), and the control group was 60％ (18/30). After treatment, the Alb (33.5 ± 7.95 g/L vs. 28.8 ± 6.10 g/L, t=2.569) in the treatment groupwas significantly higher than that in the conventional treatment group (P<0.01). While the 24 h urine protein (2.40 ± 0.92 g/24 h vs.3.60 ± 2.3 g/24 h, t=2.653), the contents of C5b-9 in urine(42.5 ± 17.50 ng/mg vs.71 ± 25.2 ng/mg, t=5.088) in the treatment group were significantly lower than those in the conventional treatment group (P<0.01). Conclusions The method of warming kidney and dredging collaterals can improve the clinical symptoms, improve serum albumin level, reduce the 24 hour urine protein and urinary C5b-9 content of idiopathic membranous nephropathy of spleen and kidney yang deficiency and blood stasis type.
ABSTRACT
ObjectiveTo observe the efficacy of acupuncture plus acupoint injection in improving the depression state and quality of life (QOL) in patients with depression after ischemic stroke (syndrome differentiated as blood stagnation obstructing collaterals).MethodAccording to the inclusion and exclusion criteria, the eligible subjects were enrolled and randomized into a treatment group and a control group. The treatment group was intervened by acupuncture plus acupoint injection, while the control group was by oral administration of Fluoxetine. They were evaluated by using the Hamilton Depression Scale (HAMD) and Barthel Index (BI) before treatment and after 2-month treatment.ResultAfter 2-month treatment, there was no significant difference in comparing the anti-depressionefficacy between the two groups (P>0.05). The BI score of the treatment group was significantly better than that of the control group after 2-month treatment (P<0.05).ConclusionAcupuncture plus acupoint injection is effective in improving the depression state in the patients with depression after ischemic stroke (syndrome differentiated as blood stagnation obstructing collaterals); after 2-month treatment, it can produce an equivalent therapeutic efficacy compared with oral administration of Fluoxetine.Acupuncture plus acupoint injection is superior to the control in improving the QOL of the patients.