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1.
China Pharmacist ; (12): 1229-1232,1235, 2017.
Article in Chinese | WPRIM | ID: wpr-617497

ABSTRACT

Vinblastines as third-generation chemotherapy drugs are widely used in the treatment of a variety of cancers.Among them, vinorelbine (NVB) is a first-line chemotherapy drug for non-small cell lung cancer, while its side effects often limit its clinical use.There are more and more clinical studies show that Chinese medicine and NVB in the chemotherapy program has a synergistic anti-tumor effect, which can improve quality of life and immunity of patients, and reduce such side reactions as gastrointestinal reactions, bone marrow suppression and so on.In this paper, the application progress in traditional Chinese medicine combined with vinblastine in the treatment of lung cancer in recent ten years was reviewed.

2.
China Pharmacist ; (12): 1578-1583, 2017.
Article in Chinese | WPRIM | ID: wpr-607489

ABSTRACT

Dopa preparations are currently first choice for the clinical treatment of Parkinson' s disease. With the application time extension and the dose increase of dopa preparations, the therapeutic effect is smaller and smaller, while the side effects are more and more significant, which have become the main problems affecting their clinical application. The current researches showed that the combination of traditional Chinese medicines and dopa preparations can improve the efficacy, decrease the dose of western medicines, reduce the adverse effects and so on. The paper reviewed the progress in the combination of dopa preparations and traditional Chinese medicines in the treatment of Parkinson' s disease in recent ten years.

3.
China Pharmacist ; (12): 1382-1386, 2017.
Article in Chinese | WPRIM | ID: wpr-621169

ABSTRACT

Doxorubicin as a member of the anthracycline-based drugs, is widely used in cancer chemotherapy, while its significant cardiac toxicity and cytotoxicity limit its application to some extent.Therefore, it's a valuable exploring topic on how to improve the effect and reduce the adverse drug reactions of doxorubicin chemotherapy.This paper attempted to analyze the literatures about TCM combined with doxorubicin in nearly 15 years, including clinical use and experimental studies, to provide reference for the clinical application.

4.
China Pharmacist ; (12): 1224-1228, 2017.
Article in Chinese | WPRIM | ID: wpr-617597

ABSTRACT

In recent years, traditional Chinese medicine combined with 5-fluorouracil (5-FU) in the treatment of tumors, especially digestive system tumors, has achieved promising results.The current research shows that the combination of traditional Chinese medicine and 5-FU can enhance tumor inhibition rate, prolong survival period of patients, improve immunity and quality of life of patients, and significantly reduce side effects such as bone marrow suppression, liver and kidney toxicity and gastrointestinal reactions and so on.Therefore, traditional Chinese medicine combined with 5-FU can have synergistic and attenuated effects.

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