Prevalencia de sífilis gestacional y congénita en una maternidad pública de Montevideo, Uruguay, en los años 2018 y 2019

Introducción: Pese a que la sífilis congénita es prevenible, la transmisión materno infantil es un problema de salud mundial. Objetivo: Determinar la prevalencia de sífilis gestacional activa y la prevalencia de sífilis congénita en el período comprendido entre 1 de enero de 2018 y 31 de diciembre de 2019 en la maternidad de referencia del sector público de Uruguay. Metodología: Trabajo observacional, descriptivo y transversal. Resultados: Se revisaron 11.949 historias clínicas siendo seleccionadas 107 pacientes en el año 2018 y 142 pacientes en el año 2019 que cumplían criterios de inclusión. La prevalencia calculada de sífilis gestacional fue de 20,8 cada 1.000 mujeres embarazadas (249/11.949), la incidencia de sífilis congénita fue de 1,0 cada 1.000 nacidos vivos (12/11.949). La mortalidad en ambos períodos fue de 0%. Conclusiones: La prevalencia de sífilis gestacional aumentó en el período 2018-2019. Esta tendencia es consonante con el aumento de la prevalencia mundial. La prevalencia obtenida de 20,8 cada 1.000 mujeres embarazadas es alta de forma comparativa con los datos nacionales, a diferencia de la incidencia de sífilis congénita (1,0/1.000) inferior a las nacionales que oscilaban de 1,4 a 2,2 cada 1.000 nacidos vivos en los últimos años.

Background: Although congenital syphilis is preventable, mother-to-child transmission is a worldwide health problem. Aim: To determine the prevalence of active gestational syphilis and the prevalence of congenital syphilis in the period between January 1, 2018 and December 31,2019 in the reference maternity unit of the public sector of Uruguay. Methods: Observational, descriptive and cross-sectional work. Results: 11,949 medical records were analyzed, 107 patients were selected in 2018 and 142 patients in 2019 who met the inclusion criteria. The calculated prevalence of gestational syphilis was 20.8 per 1000 pregnant women (249/11949), the incidence of congenital syphilis was 1.0 per 1,000 live births (12/11949). Mortality was 0% in both periods. Conclusions: The prevalence of gestational syphilis increased in the 2018-2019 period. This trend is consistent with the increase in prevalence worldwide. The prevalence obtained 20.8 per 1,000 pregnant women is high compared to national data, unlike the incidence of congenital syphilis (1.0/1,000) lower than the national ones that ranged from 1.4 to 2.2 per 1,000 live births in recent years.

Prevalência de HIV e sífilis em parturientes atendidas em uma maternidade de referência na cidade de Marabá-Pará. / Prevalence of HIV and syphilis in parturients attended in a reference maternity in Marabá, Pará

Objetivo: conhecer a prevalência da infecção pelo HIV e pelo Treponema pallidum em parturientes atendidas em uma maternidade de referência do SUS. Método: estudo transversal, descritivo com dados coletados do cartão pré-natal e dos prontuários de 480 parturientes envolvidas no estudo. Para o diagnóstico de sífilis e de infecção pelo HIV foi considerado a realização de 2 testes na gravidez e um no parto. Resultados: as prevalências de infecção pelo HIV e de sífilis na amostra estudada foram de 0,4% e 1,9% respectivamente; houve predomínio da faixa etária de 20 a 29 anos nas mulheres com VDRL reagente no parto. A maioria das parturientes frequentou o pré-natal; destas, 48,5% iniciou no primeiro trimestre; 67,6% com o primeiro teste de HIV e 76,3% com o primeiro VDRL e entre as que tiveram 6 ou mais consultas a cobertura do segundo teste foi 37,6% para VDRL e 12,4% para HIV. Ressalte-se que 107 (23,7%) e 146 (32,4%) parturientes respectivamente, só tiveram a oportunidade de fazer o VDRL e a sorologia para HIV no mo-mento do parto. Conclusão: a prevalência de HIV e sífilis em parturientes é elevada e está na dependência da qualidade da assistência pré-natal.

Objective: To know the prevalence of HIV and Treponema pallidum infections among parturients attended at SUS Maternity reference. Method: Cross-sectional and descriptive study. Data was collected from pre-natal cards and from medical records of 480 parturients attended in a Maternity reference, in Marabá, Pará, Brasil. Diagnosis of syphilis and HIV were based on two tests performed during pregnancy and one test performed in labor. Results: Prevalence of HIV infection and syphilis were respectively 0.4% and 1.9%. Predominance of reagent VDRL during labor was observed among 20-29 years old women. The majority attended prenatal care, 48.5% in the first trimester of pregnancy. Among those women 67.6% performed the first HIV test and 37.6% the first VDRL test. Among those who had six or more prenatal visits the coverage of second test was 37.6% for VDRL and 12.4% for HIV. It is worth to note that 23.7% (107/480) and 32.4% (146/480) of pregnant women performed VDRL and HIV serology only at delivery. Conclusion: High prevalence of HIV and syphilis were observed in pregnant attended in a reference maternity of Marabá, Pará, Brazil, and it was associated with quality of prenatal care.

Recent Trends of Syphilis Prevalence in Normal Population in Korea-1990

From January to December of 1990, we have evaluated VDRL reactivity among 17,142 apparently normal Korean adults which consisted of 9,151 blood donors in Seoul area, 2,682 pregnant woman delivered at Severance Hospital, Yonsei University and 5,309 physical examinees. The VDRL-positive rates were 0.3% in the blood donors, 0.1% in the pregnant women and 0.8% in the physical examinees but the rates were higher in the age group of 50 years or older. The VDRL titers were below 1:2 in 94% of the VDRL-positive pregnant women and physical examinees. From the comparison of the results obtained by the present author group since 1977, i.e., 2.5 % in 1977, 1.1 % in 1981, 0.6 % in 1986 and 0.4 % in 1990, it is evident that the prevalence of syphilis in Korea is continually decreasing.

Recent trends of syphilis prevalence in normal population in Korea-1986

The 6,097 blood donors in Seoul area, the 1,883 pregnant women delivered at Severance Hospital and the 5,136 physical examinees were evaluated for VDRL reactivity. Also, the FTA-ABS and TPHA tests were performed on those who were VDRL-positive, and the 19S (IgM)-FTA test were done on the subjects who were reactive for the FTA-ABS and TPHA tests. All the subjects were over the age of 20 and the study period was conducted from January of 1986 through December of 1986. The results are summarized as follows: 1. VDRL-positive rates were 0.5% in the blood donors, 0.6% in the pregnant women and 0.8% in the physical examinees. 2. The quantitative test of VDRL resulted in low titer below 1:4 in 96% of VDRL-positive pregnant women and physical examinees. 3. The 19S (IgM)-FTA test was reactive in 3 of 12 treated subjects (25%) and 4 of 10 untreated subjects (40%). From the results it is clear that the prevalence of syphilis is continually decreasing compared to the mid 1970's and the early 1980's.

Syphilis Prevalence in Teagu Hope Village / 대한피부과학회지

Serologic tests for syphilis, including VDRL and TPHA tests, and Physical examination were carried out on 1, 605 subjects who lived in Taegu Hope Village, a social welfare center, from April, 198R to May, 1985. We prepared this study comparing with previous reports for healthy individuals and prostitutes. The results were as follows, The reactive rate of VDRL. qualitative test was 11. 6% in total, 10. 3%, in men and l3. 5%. in women. The reactive rates of VDRL. qualitative tests were highest in 7 th decade as 28, 7% and followed by 6 th decade as 16. 7% the decacile as 16. 0% 8 th decade as 14,3% 4th decade as 8. 8% and 3rd decade as 5. 9%, 3 In ]Hg sero-positive subjects, VDRL quantitative tests were done, and 35. 5% were reacted with 1: 8 or high and 29. 0% had one or more syphilitic lesions. 4 In 54 subjects who had one or more syphilitic lesions, 19 had chancres, 17 had alopecia syphilitica, 7 had rnaculopapular syphilid, 7 had condylomata lata. 3 had papular syphilid, and 1 had maculopapular syphilid and alopecia syphilitica. The biological false positive rate was 10. 1,4 in 138 VDRL reactive subjects, using 1;he TPHA test standard.