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1.
Acta neurol. colomb ; 30(1): 49-56, ene.-mar. 2014. ilus, tab
Article in Spanish | LILACS | ID: lil-724890

ABSTRACT

El Lupus Eritematoso Sistémico (LES) es la enfermedad autoinmune mas frecuente y con mayor número de manifestaciones neuropsiquiátricas descritas. Las alteraciones neuropsicológicas se incluyen dentro de este grupo de manifestaciones, con una frecuencia mayor al 50% en niños, con compromiso principalmente de la memoria de trabajo, memoria verbal y velocidad de procesamiento, lo cual se relaciona con el rendimiento y asistencia escolar y en gran medida de la calidad de vida. Este artículo revisa la frecuencia de las alteraciones neuropsicológicas en pacientes pediátricos con Lupus Eritematoso Sistémico, la fisiopatología, las diferentes pruebas diagnósticas reportadas hasta el momento, así como el impacto escolar de la enfermedad.


Systemic Lupus Erythemathosus is the most frequent autoinmune disease and with more neuropsychiatric symptoms. The Neuropsychological impairment is between this group of manifestations, with a higher frequency in children than 50%, with decline in work Memory, verbal Memory and speed processing as major alterations, these alterations are related with academic achievment and school attendance with afectation in quality of life. This article review the frequency of Neuropsychological impairment in Pediatric patients with Systemic Lupus Erythemothosus, the pathophysiology, different diagnosis test and the impact of the disease in School.

2.
Psicol. teor. pesqui ; 27(4): 485-490, dez. 2011.
Article in Portuguese | LILACS | ID: lil-611161

ABSTRACT

Manifestações neuropsiquiátricas são comuns no lúpus eritematoso sistêmico (LES), especialmente depressão, ansiedade e psicose. O estresse psicológico e o uso de corticóide têm sido responsabilizados pelas manifestações psicopatológicas. Objetivou-se realizar revisão de literatura sobre a eficácia da intervenção psicológica no tratamento do LES, utilizando-se pesquisas em bases de dados, através dos descritores "psychotherapy" and "lupus", incluindo-se os ensaios clínicos randomizados e os estudos prospectivos. Foram encontrados seis artigos, sendo quatro ensaios clínicos randomizados e dois estudos prospectivos. Cinco artigos encontraram evidências de acentuada melhora nos pacientes que tinham acompanhamento psicológico e apenas um não encontrou tal evidência. Concluiu-se que a intervenção psicológica pode ser uma ferramenta importante no tratamento do LES.


Neuropsychiatric manifestations, especially depression, anxiety and psychosis, are common in systemic lupus erythmatosus (SLE). The psychological stress and the use of corticoids have been blamed for these psychopathological manifestations. A literature review was realized on the efficacy of psychological interventions in the treatment of SLE, using research data bases, through the descriptors "psychotherapy" and "lupus", including randomized clinical trials and prospective studies. Six articles were found, of these, four were randomized clinical trials, and two prospective studies. Five articles related evidence of pronounced improvement in patients that had psychological follow-up and one article did not found such evidence. Psychological intervention can be an important tool in the treatment of SLE.


Subject(s)
Humans , Male , Female , Lupus Erythematosus, Systemic , Psychotherapy , Efficacy , Stress, Psychological
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