Trauma for the vulnerable: Real or imagined?

@#Linn is a twenty-year-old female who grew up silently competitive while feeling inferior, and still excelling academically in the background of bullying and social exclusion. This report proposes that the vulnerability to trauma or to the perception of being traumatized can be related to the individual’s level of narcissism. Trauma-associated narcissistic symptoms (TANS) are a result of experiencing a stressor as an affront to the grandiose self. A traumatic disequilibrium occurs in a narcissistically vulnerable self. In both TANS and posttraumatic stress disorder (PTSD), secondary symptoms of anxiety and depression can significantly color the patient’s clinical presentation. Individuals can develop both TANS and PTSD, displaying a mixed clinical presentation. Psychotherapy with the primary goal to restore narcissistic equilibrium is recommended.

Research progress in mechanisms of tumor-associated neutrophils promoting tumor metastasis / 中国肿瘤临床

Neutrophils are the most abundant leukocytes in the peripheral blood and play an important role in the immune response. However, there is growing evidence indicating that in addition to the immune response, neutrophils also have a crucial role in tumor development, especially in the process of invasion and metastasis. According to current research, depending on their phenotype, neu-trophils appear to be either anti-metastasis (N1) or pro-metastasis (N2). However, the role of tumor-associated neutrophils (TANs) in the metastasis of tumors is relatively complex and lacks a systematic introduction. This review mainly introduces TANs and focuses on the mechanism of TANs in promoting tumor invasion and metastasis. Finally, the possibility of TANs as an anti-tumor treatment strate-gy is discussed.

Research progress of tumor-associated neutrophils / 实用肿瘤学杂志

Tumor growth depends on the tumor microenvironment(TME).Tumor-associated neutrophils(TANs)are important inflammatory cells in TME.TANs are divided intoN1type with anti-tumor effect andN2type of tumor-promoting effect.Therefore,TANs have both beneficial and harmful aspects of the body.A large number of studies have been shown that TANs affect tumor formation,metastasis,angiogenesis and immune response,regulated by the secretion of cytokines and chemokines.This review will summarize the biological characteristics of TANs,and tumor development,prognosis and treatment of tumor as well as research progress of the relationship between TANs and tumor.