ABSTRACT
Telocyte(TC)is a novel type of interstitial cell, which has been identified in various organs and tissues of both humans and animals.Recent studies have confirmed that TC plays crucial roles in regulating tissue and organ development, maintaining tissue homeostasis, participating in tissue repair and regeneration, and modulating the immune response.This article provides a comprehensive review of the current research progress on the distribution, immunophenotype, and cellular functions of TC in the respiratory, circulatory, digestive, urinary, reproductive, locomotor systems, and other organs and tissues during fetal and neonatal development.This review aims to serve as a valuable reference for future investigations into the structure and functions of TC.
ABSTRACT
Telocytes (TCs) are a kind of interstitial cells recently identified,which distribute in the heart,lung,liver,kidney,brain and some other organs.These cells are characterized by a small cell body and extremely long and thin telopodes (Tp).The TPs arranged in moniliform aspect with alternation of thin segments and small dilations,forming a complex 3D network with the surrounding cells.More and more researches show that TPs have a role in injured tissue repairement directly or indirectly.This review focus on its function of tissue repair and the possible mechanism.