ABSTRACT
Objective To study the chemical constituents from the stems of Marsdenia tenacissima.Methods The chemical constituents were isolated by various column chromatography and their structures were identified by spectral and chemical analysis.Results Two pregnane glycosides were isolated from the stems of M.tenacissima and identified as3-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1 →4)-β-D-oleandropyranosyl-11α-Otigloyltenacigenin B,named as tenacigenoside I(1)and 3-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-Dallopyranosyl-(1→4)-β-D-oleandropyranosyl-11α,12β-di-O-acetyltenacigenin B,named as tenacigenoside K(2).Conclusion Compound 1 is a new compound,1H-NMR and 13C-NMR data of compound 2 are reported for the first time.
ABSTRACT
Objective: To study the chemical constituents from the stems of Marsdenia tenacissima. Methods: The chemical constituents were isolated and purified by various column chromatographic methods. Their structures were identified on the basis of spectral data and chemical analysis. Results: Two pregnane glycosides were isolated from the stems of M. tenacissima and identified as 3-0-β-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-allopyranosyl- (1→4)-β-oleandropyranosyl-11α-O-tigloyltenacigenin B, named as tenacigenoside I (1); 3-O-β-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl- β-allopyranosyl-(1→4)-β-oleandropyranosyl-11α, 12β-di-O-acetyltenacigenin B (tenacigenoside K, 2). Conclusion: Compound 1 is a new compound and compound 2 is obtained from the M. tenacissima for the first time.