A rare case of squamous cell carcinoma in situ arising in mature cystic teratoma

Mature cystic teratoma (MCT) is the most common ovarian tumor. Secondary malignant tumors rarely arise in MCTs, and squamous cell carcinoma (SCC) is the most common form of such tumors. MCT-derived SCC in situ (CIS) is mostly found together with invasive SCC; it is seldom detected alone. A 44-year-old woman with breast cancer was found to have a left ovarian cyst (size > 8 cm) before treatment. She underwent bilateral salpingo-oophorectomy, and frozen biopsy showed MCT with focal proliferation of squamous epithelium and mild atypism. However, definitive pathologic diagnosis confirmed CIS arising in MCT. In addition, germline BRCA 1/2 test and human papillomavirus test of tumor tissue yielded negative results. This report is the first case of its kind in Korea. Our report can aid in clinical decision making and serve as a basis for follow-up studies on this rare type of CIS arising in MCT.

A review of laparoscopic management of ovarian dermoid cysts: a series of 53 cases

This is a retrospective survey of 53 patients who had laparoscopic removal of benign dermoid cyst in our institution from 2000 to June 2005. Preoperative transvaginal sonography led to the correct diagnosis in 94.6 percent of cases and 56.6 percent of cases were diagnosed incidentally by sonography. The overall mean tumor size was 4.78 +/- 1.56 cm. The mean tumor size was 5.21 +/- 1.50 cm and 4.1 +/- 1.38 cm for spilled and unspilled cysts, respectively. Intraoperative spillage occurred in 61 percent of cases. No case of chemical peritonitis was noted. No major intraoperative or postoperative complications were reported.