Investigation on the IGF-1 and lipid level in term small for gestational age infants within 24 hours postnatally / 中国新生儿科杂志

Objective:To study the insulin-like growth factors-1 (IGF-1) and lipid level of term small for gestational age (SGA) infants within 24 hours postnatally and to explore the correlation between IGF-1 and blood lipids.Methods:A prospective study was conducted on singleton term SGA and appropriate for gestational age infant (AGA) who were delivered and admitted to the neonatal ward of Guangdong Women and Children Hospital within 24 hours after birth from May 2020 to January 2021, and the infants were divided into SGA and AGA groups to compare the differences in IGF-1 and lipid levels within 24 hours after birth and to analyze the correlation between IGF-1 and lipids.Results:A total of 95 cases in the SGA group and 84 cases in the AGA group were included in the study. The proportion of infants with IGF-1 <25 ng/ml was significantly higher in SGA group (87.4%) than in the AGA group (52.4%). It was also found that the proportion of infants with IGF-1 <25 ng/ml in SGA was significantly higher than that in AGA within different gender composition groups, early-term and full-term births groups. The triglyceride (TG) level was higher in the SGA group than that in the AGA group, but the high-density lipoprotein cholesterol (HDL-C) level was lower than that in the AGA group ( P<0.05). IGF-1 level within 24 hours postnatally in SGA and AGA was positively correlated with HDL-C levels ( P<0.01) and negatively correlated with TG ( P<0.01), and HDL-C level was a predictor of IGF-1. Conclusions:Compared with term AGA, SGA term infants showed insufficient IGF-1 and HDL-C secretion and high TG within 24 hours after birth. Nutritional support for SGA should be given promptly after birth to avoid hypoglycemia and to stimulate IGF-1 secretion.

Summary of best evidence for management of labor course induced by oxytocin drip in term pregnancy / 中国实用护理杂志

Objective:To search, evaluate and summarize the best evidences related to induction of labor by oxytocin infusion in pregnant women with full-term pregnancy, and to provide reference for clinical practice in order to reduce the complications during labor, such as the proportion of instrument delivery, prolonged labor duration, uterine rupture, postpartum hemorrhage, etc. Standardize the management process of induction of labor with oxytocin, improve the satisfaction of pregnant women to participate in the decision of induction of labor, and improve the outcome of the newborn.Methods:Take the evidence-based nursing method, in view of the full-term pregnancy pregnant women oxytocin drip induced labor evidence-based labor management problems, nearly 10 years related literature retrieval from January 1st 2011 to April 9th, 2021, the Australian JBI evidence-based health care center of literature quality evaluation criteria and evidence classification system, all kinds of research evaluation and classification of retrieval.Results:Early detection to 340 articles, and eventually into 9 articles, including 1 clinical decision, 6 guides, 2 pieces of system evaluation. Totally 45 pieces evidences related to induction of labor by oxytocin infusion in pregnant women with full-term pregnancy were sumarized, including induced labor time, oxytocin side effects, induced labor before evaluation, induced labor of guardianship, infusion solution, such as health education, and other seven aspects.Conclusions:The present study summarized 45 pieces of best evidence on the management of labor induced by oxytocin infusion during term pregnancy, which provided some evidence-based basis for midwives, obstetric nurses and managers. Through the application of the best evidence, it is beneficial to improve the outcome of pregnant women in the neonatal perinatal period, standardize the process of inducing labor with oxytocin, and improve the quality of obstetric care.

Efficacy and safety of prostaglandins vs double balloon catheter in inducing labor: a meta-analysis

Background: To compare the efficacy and safety of double‐balloon catheter with prostaglandin E2 (PGE2) in induction of labor.Methods: We searched electronic sources from Medline, Scopus, PubMed, Science Direct and Cochrane Library Database of Systematic Reviews. Only randomized controlled trials and observational studies comparing the PGE2 agents with double-balloon catheter for cervical ripening and labour induction in women with unfavorable cervix were included in the analysis. The main outcomes included vaginal delivery rate within 24 hours and cesarean delivery rates. We calculated relative risks and mean differences using fixed effects and random‐effects models.Results: Prostaglandin was more favourable for vaginal delivery within 24 hours compared to double balloon catheter, but was not statistically significant (RR 1.17: 95% CI 0.96-1.42 p =0.12). The induction to delivery time yielded a non-significant result that again favors prostaglandin (SMD 0.02 CI:0.18,0.22, p = 0.86). There was no significant difference in the cesarean delivery rates between the two groups (RR 1.02: 95% CI 0.92-1.14, p = 0.68). Uterine hyperstimulation and Neonatal Intensive Care Unit (NICU) admissions were significantly higher with prostaglandin. (RR 0.09: CI 0.04, 0.22 p<0.00001 and RR 0.75 CI: 0.62,0.90 p=003).Conclusions: There is no significant difference in the success of induction of labour between use of PGE2 and double balloon catheter. Uterine hyperstimulation and NICU admissions were significantly higher in Prostaglandin group.

Study of maternal and fetal outcome in pregnancy beyond 40 weeks: a prospective observational study at a tertiary institute

Background: Prolonged pregnancy is one that exceeds 42 0/7weeks. Management of prolonged pregnancy is very challenging in modern obstetrics.Methods: It is prospective observational study in department of Obstetrics and Gynecology, Shri B.M Patil medical college and Research center, deemed to be University, Vijayapur, North karnataka. Study period was from January 2018 to January 2019.Results: Total of 186 pregnant women were included in the study. Results in terms of age, gravidity, gestational age, time of induction, mode of delivery, neonatal outcome and maternal complications.Conclusion: Pregnancies beyond 40 weeks require early detection, effective fetal monitoring and proper planning of labour. In pregnancies beyond 40 weeks, decision of induction should be taken cautiously as early induction leads to failure of induction and increased rates of lower (uterine) segment Caesarean section (LSCS), while delayed induction leads to increased fetal complications.

Maternal and fetal factors associated with non detection of fetal growth restriction at term: a retrospective study

Background: Fetal growth restriction (FGR) is one of the major factors of perinatal morbidity and mortality. Aim was to study the maternal and fetal risk factors associated with non- detection of fetal growth restriction.Methods: A retrospective analysis was done at a tertiary care hospital. 280 term newborn cases weighing <2.5 kg were selected and they were divided into two groups, Group I- FGR detected cases by ultrasound, and group II- FGR non detected cases. Data was collected from the labour room registers.Results: Incidence of FGR found to be 6.8%.The maternal biological factors found to be significantly associated with fetal growth restriction were gestational hypertension, chronic hypertension and anemia. Fewer ANC visits was associated with non-detection of FGR cases. Detection of FGR cases were more if the birth weight found to be <2 kg when compared to non detection of FGR cases.Conclusions: Anaemia and fewer ante natal visits were associated with non detection of FGR at term when compared with antenatally detected FGR patients.

Relationship between the amniotic fluid index at term and the perinatal outcome

Background: Amniotic fluid index (AFI) is commonly used to estimate amniotic fluid volume. A proper AFI is between 10 and 24 centimetres. If it is below 5 cm, it is can represent oligohydramnios, and in case AFI is above 24 cm, it can represent polyhydramnios. This study was undertaken to determine whether measuring AFI at term is useful in the prediction of perinatal outcome.Methods: A prospective study of 250 pregnant women with gestational age between 37 and 42 weeks was conducted at Sola Civil Hospital. AFI was measured in each patient using the Phelan’s technique and the perinatal outcome was studied. The results were analysed and presented in the form of tables and graphs.Results: Total 250 patients were studied. Out of them, 33 patients (13.2%) had AFI <=5, 215 (86%) had AFI between 6 and 24; and 2 patients (0.8%) had AFI >=25.19 out of 33 (57.57%) patients with AFI <= 5, had to undergo caesarean section, out of which, 12 caesarean sections (63.15%) were taken for non-reassuring foetal status. 36.27% (78/215) of patients with AFI between 6 and 24 underwent caesarean section, out of which 38.46% (30/78) underwent caesarean section for non-reassuring foetal status.Conclusions: In the presence of oligohydramnios, the rates of LSCS due to foetal distress, the occurrence of low Apgar score and of low birth weight are higher than in patients with normal liquor at term. Thus, measuring the amniotic fluid index at term can be helpful in the prediction of perinatal outcome.

Sweeping of the fetal membranes and its effect on duration of pregnancy in low risk cases

Background: This study aimed to determine effectiveness of sweeping of membranes on the duration of pregnancy at term, and its effect on maternal and neonatal outcomes.Methods: In this prospective study, 145 women with uncomplicated pregnancy at 39 weeks or more gestation who were attending regular ANC clinic, were recruited for study, out of them 60 were cases (sweeping group) and 85 were control (no sweeping group). Primary outcome measure was occurrence of spontaneous labour and total duration of pregnancy. Other outcome measures included were interval of onset of labour from membrane sweeping, incidence of premature rupture of membranes, total duration of active labour, mode of delivery, rate of caesarean section and causes, and neonatal and maternal outcome.Results: There were no statistically significant differences between the two groups regarding maternal age, parity and bishops score at recruitment. There was a significant difference observed in spontaneous labour rate and interval time between recruitment to delivery in groups. There was no significant difference regarding mode of delivery, maternal and fetal outcomes.Conclusions: Membrane sweeping is a safe procedure that reduces the incidence of post-term pregnancies if applied at term.

Maternal outcome of primigravida patient with term pregnancy with engaged versus unengaged foetal head at onset of labour

Background: The primigravida are a group at risk as their capacity of child bearing has never put to the test, “primigravida is a dark and untired horse". The potential for future child bearing is determined by outcome of first labour. Hence, if first pregnancy results in normal healthy child, patient is mentally better prepared for subsequent pregnancies. Foetal head is said to be engaged when its biparietal diameter, the greatest diameter in an occiput presentation, passes through the pelvic inlet. Unengagement of head in primigravida has long been considered a possible sign of cephalopelvic disproportion.Methods: The study had 220 primigravida of which 110 had unengaged head as study group and 110 engaged head as controls. Data collection was done and the course of labour in all the patients recorded on partograph and all the patients were studied in detail. Engagement of the head was defined on the basis of Second Pawlik’s grip and Crichton’s fifth’s formula.Results: Our study shows that higher age group had more number of cases with unengaged head. The patient with engaged head had higher number of vaginal delivery than study group with unengaged head. More number of LSCS i.e. about 39.1% in study group as compared to 21% of controls is statistically significant difference (p value 0.05).Conclusions: We can conclude that primigravida with unengaged foetal head at onset of labour may deliver vaginally with minimal maternal morbidity, if proper   monitoring and maintenance of partogram is done.

Efficacy of Mefipristone for induction of labour in late term pregnancy

Background: Late-term pregnancy defined as one that has reached between 41 0/7 weeks and 41 6/7 weeks of gestation is associated with an increased maternal morbidity as well as an increased risk of fetal and neonatal mortality and morbidity. Mifepristone, an anti-glucocorticoid and antiprogesterone, though not an oxytocic increases uterine activity and causes cervical effacement and dilatation and improves the Bishop score without over/hyper stimulation of uterus. Increased maternal and fetal mortality from late term pregnancy could be prevented by induction of labour. The objective of this study was to know the efficacy of single dose of oral mifepristone in induction of labour in late term pregnancy and to assess the induction delivery interval in the study population.Methods: This was a prospective interventional study conducted in Department of Obstetrics and Gynaecology at BGS Global Institute of Medical Sciences, Bengaluru. 100 Women with late term pregnancy who fulfilled the inclusion and exclusion criteria were considered for the study after an informed written consent.Results: 73.5% (n=36) of multigravida and 80.4% (n=41) of prim gravida showed improvement in the Bishop score post induction with mifepristone and majority (89.79 % primigravida and 84.31% multigravida) of the study population had vaginal delivery. Multigravida (73.5%) had less induction delivery interval (less than 48hours) compared to primigravida (19.6%).Conclusions: Mifepristone, a progesterone antagonist causes a significant improvement in the Bishop’s score and is associated with an increased rate of vaginal deliveries.

Embarazo abdominal postérmino: Reporte de un caso / Post-term abdominal pregnancy, a case report

Abdominal ectopic pregnancy is a dramatic situation for the woman's health. It is a rare pathology that proves to be a difficult test even for the most experienced gynecologists in diagnostic ability, decision-making and surgical technique. We present the case of a hospitalized post-term ectopic abdominal pregnancy with a dead fetus inside the chorioamniotic sac and the placenta implanted on vital abdominal viscera. We describe the clinical data, operative findings and conservative management of the retained placenta, followed by a bibliographic review on the subject.

El embarazo ectópico abdominal representa una situación dramática para la salud de la mujer. Al ser una patología poco frecuente, resulta al ginecólogo una prueba difícil para habilidad diagnóstica, capacidad de decisión y técnica quirúrgica, incluso para el más experto. Se presenta un caso de embarazo ectópico abdominal postérmino, que llegó con óbito fetal dentro de la bolsa corioamniótica y la placenta implantada sobre vísceras abdominales. Se describe los datos clínicos, hallazgos operatorios y el manejo conservador de la placenta retenida, y se hace una revisión bibliográfica del tema.

Prognostic effect of intrauterine pregnancy induced by different methods of cervical ripening / 中国基层医药

Objective@#To investigate the effect of different cervical ripening methods on induction of labor in term pregnancy.@*Methods@#160 cases of labor induction of full-term pregnancy primipara were selected as the research subjecs.According to the different methods of cervical ripening, they were divided into two groups.The observation group (n=80) underwent dinoprostone suppositories induced labor, the control group (n=80) received intravenous infusion of small dose of oxytocin.The cervical Bishop score, cervical ripening effect, induction of labor, mode of delivery, neonatal outcome were observed in the two groups.@*Results@#Before treatment, the Bishop scores of the two groups had no statistically significant difference (t=0.436, P>0.05). After treatment for 24h, the Bishop score of the observation group was (8.3±2.6)points, which was higher than (5.9±2.0)points of the control group (t=6.544, P<0.05). In the observation group, the total effective rate of cervical ripening was 95.0%, which was higher than 66.2% of the control group (Z=-5.716, P<0.05). The duration of labor in the observation group was (12.6±4.5)h, which was significantly shorter than (21.7±7.8)h in the control group (t=9.039, P<0.05). The total labor, postpartum hemorrhage volume had no statistically significant differences between the two groups (t=2.298, 1.102, all P>0.05). In the observation group, 66cases (82.5%) were vaginal delivery, 14cases(17.5%) were cesarean section, those were 49cases(61.2%) and 31cases(38.8%) in the control group.The delivery mode of the observation group was significantly better than that of the control group(χ2=8.935, P<0.05). There were no statistically significant difference between the two groups in neonatal birth weight and postnatal 1min and 5min Apgar scores (all P>0.05).@*Conclusion@#Parturient with dinoprostone suppositories full-term pregnancy abortion can improve the cervical Bishop score and cervical ripening effect, improve the quality of delivery, it is better than oxytocin, and worthy of clinical application.

Analysis of Risk Factors for Cesarean Section after Induction of Late-term Pregnancy / 中国医科大学学报

Objective To explore the risk factors for cesarean section after induction of late-term pregnancy. Methods This study enrolled 275 primiparas with a single cephalic fetal presentation,admitted to our hospital between December 2010 and December 2016 for induction of late-term pregnancy. After induction,80 underwent cesarean section and 195 had a normal vaginal delivery. Clinical data were collected and analyzed retrospectively. Single factor analysis and two categories of logistic regression analysis were used to determine the independent risk factors for cesarean section after induction of late-term pregnancy. Results Single factor analysis showed that the differences between the two groups in maternal height,cervical Bishop score before induction of labor,latent phase,intrapartum amniotomy,intrapartum oxytocin,meconium stained amniotic fluid,and birth weight were statistically significant (P < 0. 05). Multivariate analysis showed that maternal height,cervical Bishop score before induction of labor,and latent phase were independent risk factors for cesarean section after induction of late-term pregnancy. Conclusion Late-term pregnant primiparas with short stature,low Bishop score,or a long latent phase should have comprehensive prenatal maternal-fetal assessment,and a reasonable delivery mode should be chosen to avoid adverse outcomes.

Comparison of two kinds of cervical ripening balloons in promoting full-term pregnancy cervical mature and inducing labor / 实用医学杂志

Objective To explore the clinical effects of single-cavity and COOK cervical ripening balloon in promoting full-term pregnancy cervical mature and inducing labour. Methods 126 puerpera who were expect-ant in the obstetrics department of our hospital were selected from January 2016 to June 2017,and all of the puer-pera were induced labor by cervical ripening balloon.In 61 of them,single-cavity balloon was used,and 65 cases were induced labor by COOK balloon. Determining the cervical ripening situation,the time needed for inducing efficient uterine contraction,the first stage of labor time,the total labor time,vaginal delivery rate,natural labor situation,postpartum hemorrhage,amniotic fluid turbidity,puerperal infection and newborn asphyxia of the two groups.Results the time needed for inducing efficient uterine contraction of the two groups were(16.39±2.68)h, (14.54 ± 3.30)h,and the two groups were statistically different(P<0.05).There were no statistically significant differences in other items of two groups(P>0.05).Conclusion single-cavity balloon and COOK balloon are sim-ilar in promoting full-term pregnancy cervical ripening.The difference is that the time needed for inducing efficient uterine contraction of the single-cavity balloon is longer than COOK balloon,but have no adverse effect to the puer-pera and the newborn.Both types of balloons are recommended to be used in promoting full-term pregnancy cervical ripening and inducing labor.

Comparación resultados perinatales en gestantes con y sin alteración de doppler de acm en fetos de crecimiento normal / Comparison of perinatal outcomes in pregnant women with and without alteration of acm Doppler in normal growth fetuses

Objetivo:Comparar los resultados perinatales en gestantes cony sinalteración de Doppler de la arteria cerebral mediaen fetos de crecimiento normal. Hospital Niño Jesús, Barranquilla,periodo julio 2017 ­abril 2018.Materiales y métodos: Se presenta un estudio analítico prospectivounicentrico, diseñado con el objetivo de comparar los resultados perinatales en gestantes con y sin alteración de Dopplerde la arteria cerebral media en fetos de crecimiento normal. Hospital Niño Jesús, Barranquilla, periodo julio 2017 ­abril 2018.Resultados:Muestra compuesta por un total de 200 pacientes, 180 pacientes que no presentaron alteración de Doppler de la arteria cerebral media con media en su percentil de 47.6 ± 25.0 y 20 pacientes cuyo percentil estuvo por debajo de 5 con media de 3.5 ± 1.0, no se encontraron diferencias significativas respecto a aumento de resultados perinatales adversos en ninguno de los grupos de estudio, la tasa de cesárea Aumento de la tasa de cesárea OR: 5.5 p: 0.001.Conclusiones:no existen diferencias estadísticamente significativas al comparar los resultados perinatales de las gestantes con y sin alteración de Dopplerde la arteria cerebral media en fetos de crecimiento normal, se evidencio un aumento estadísticamente significativo en la tasa de cesáreas en el grupode arteria cerebral media alterada

Objective:To compare the perinatal results in pregnant women with and without Doppler alteration of the middle cerebral artery in fetuses of normal growth. Hospital Niño Jesús, Barranquilla, period July 2017 -April 2018.Materials and methods: We present a unicentric prospective analytical study, designed with the aim of comparing perinatal outcomes in pregnant women with and Doppler alteration of the middle cerebral artery in normal growth fetuses. "Hospital Niño Jesús, Barranquilla", period July 2017 -April 2018.Results:Sample composed of a total of 200 patients, 180 patients who did not present a Doppler alteration of the middle cerebral artery with a percentage of 47.6 ± 25.0 and 20 patients whose percentage was below 5 with an average of 3, 5 ± 1.0. there are no differences between the results of the study results, Increase in the OR: 5.5 p: 0.001.Conclusions: there are no statistically significant differences when compared with the perinatal results of pregnant women with and without Doppler alteration of the cerebral middle artery in fetuses of normal growth, a statistically significant increase in the rate of cesarean sections in the cerebral artery group was evidenced altered media

Sonda de Foley transcervical-oxitocina u oxitocina sola para la inducción del parto en embarazos a término / Transcervical Foley catheter­endovenous oxytocin or oxytocin alone for induction of labor in term pregnancres

Objetivo. Comparar la efectividad de la sonda de Foley transcervical más oxitocina con oxitocina endovenosa sola, en la inducción del parto en embarazos a término. Diseño. Estudio de casos y controles. Institución. Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela. Participantes. Embarazadas a término que asistieron para maduración cervical e inducción del parto asignadas al azar con sonda de Foley transcervical - oxitocina endovenosa (grupo A) u oxitocina endovenosa (grupo B). Principales medidas de resultado. Características generales, intervalo inicio de la inducción y el parto, tasa de parto vaginal, complicaciones maternas, variables perinatales y efectos adversos. Resultados. No se encontraron diferencias estadísticamente significativas entre los grupos con relación a las características generales (p = ns). Las pacientes del grupo A presentaron un intervalo significativamente menor desde el inicio de la inducción hasta el parto comparado con las pacientes del grupo B (p < 0,05). No se hallaron diferencias significativas con relación a la tasa de partos vaginales entre los grupos (p = ns). No hubieron diferencias en los valores de Ápgar al minuto y a los 5 minutos entre los recién nacidos de ambos grupos (p = ns). El efecto adverso más común en ambos grupos fue náuseas, pero no se hallaron diferencias estadísticamente significativas entre los grupos en la frecuencia de efectos adversos (p = ns). Conclusión. El uso sonda de Foley transcervical más oxitocina disminuye el intervalo entre el inicio de la inducción y el parto comparado con la oxitocina sola, con una incidencia similar de efectos adversos maternos y perinatales.

Objective: To compare the effectiveness of transcervical Foley catheter - oxytocin with oxytocin alone for labor induction in term pregnancies. Design: Case-control study. Setting: Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela. Participants: Pregnant women undergoing cervical ripening and labor induction were randomly assigned to be treated with transcervical Foley catheter - oxytocin (group A) or oxytocin alone (group B). Main outcome measures: General characteristics, interval between beginning of induction and delivery, vaginal birth rate, maternal complications, perinatal variables, and adverse effects were evaluated. Results: There were no significant differences between groups in general characteristics (p = ns). Patients of group A showed a shorter interval between the beginning of induction and delivery compared with patients in group B (p < 0.05). There was no significant difference in vaginal birth rate between groups (p = ns). Newborns of both groups had similar mean values of Apgar scores at 1 minute and 5 minutes (p = ns). The most common adverse effect in both groups was nausea, but there were no significant differences between groups in frequency of adverse effects (p = ns). Conclusions: Use of transcervical Foley catheter - oxytocin shortened the interval between beginning of induction and delivery compared with oxytocin alone, with similar incidence of maternal and perinatal adverse effects.

Establishment of reference range for thromboelastography in pregnancy / 中国输血杂志

Objective To establish a reference range for the normal value of thromboelastography (TEG) in pregnant females.Methods According to the results of pregnancy and physical examination,166 pregnant females and 64 healthy females without pregnancy were selected as the pregnant group and the non-pregnant control group,respectively.The TEG value and the traditional coagulation index were measured.The TEG parameters of the two groups were compared and analyzed,establishing a reference range for the parameters.We further analyzed the effect of full-term pregnancy on TEG results and the correlation between traditional coagulation index and TEG test results.Results The traditional coagulation index and TEG test results of the pregnant females andthe non-pregnant females were significantly different.According to the results,a new TEG reference range was established:R 3.9-7.5 min,K 1.0-2.4 min,α 57.6°-74.9°,MA 55.7-75.7 mm,LY30 0-0.56％,CI(-0.97)-3.6.Full-term pregnancy had no significant effect on TEG results.In addition to LY30,other parameters of TEG had some correlation with the traditional coagulation index.Conclusions The general TEG reference range does not apply to pregnant females and established TEG normal reference range for pregnant females can be applied for clinical use.

Term Live Secondary Abdominal Pregnancy: A Case Report

Term, live abdominal pregnancy secondary to rupture of a uterine rudimentary horn is a rare condition. Pregnancies conceived in the rudimentary horn of the uterus usually rupture during early gestation and present as a catastrophic event. However, rarely, after rupture of the uterine horn the foetus may continue to grow in the abdominal cavity and reach term gestation. A primigravida with a term pregnancy was referred to our centre for caesarean section with ultrasonography findings of transverse lie and placenta previa. During surgery, a live baby was extracted from the abdominal cavity, revealing a bicornuate uterus with rupture of the rudimentary horn. The early peroperative diagnosis and prompt control of the bleeding with excision of the rudimentary horn and transfusion of multiple blood products saved the patient’s life. The case is presented for its rarity and to highlight the importance of a high index of suspicion in cases presenting with abnormal foetal presentation.

Anemia materna y peso al nacer en productos de embarazos a término / Maternal anemia and birth weight in term pregnancy products

OBJETIVO: Relacionar la anemia materna con el peso al nacer (PAN) en mujeres con embarazos a término atendidas en la emergencia obstétrica de la Maternidad "Dr. Armando Castillo Plaza", Maracaibo, Venezuela. MÉTODOS: Investigación correlacional con diseño no experimental y transeccional, donde se evaluaron 200 embarazadas en fase activa del trabajo de parto, a quienes se les determinaron los valores de hemoglobina (Hb), hematocrito (Hcto) e índices hematimétricos, para luego correlacionarlas con el PAN. RESULTADOS: Los valores de Hb oscilaban entre 8,4 ± 1,0 g/dl y 11,6 ± 0,64 g/dl, mientras que los de Hcto fueron de 28,8 ± 3,3% y 38,9 ± 2,2%, anémicas y no anémicas, respectivamente. Los índices hematimétricos mostraron valores referenciales normales en ambos grupos. El PAN de los recién nacidos de madres anémicas estaba disminuido en 12,39% (-420 g) al compararse con los pesos de los neonatos de madre sin anemia (2.970 ± 0,43 g vs. 3.390 ± 0,32 g; p<0,0001). El BPN fue más frecuente en el grupo de madres anémicas, las cuales mostraron un mayor riesgo, aunque no significativo (15% vs. 10%; OR IC95% 1,558 [0,676-3,728]; p>0,05). Se demostró una relación directamente proporcional y significativa entre los valores de Hb - PAN (r=0,439; p<0,0001). CONCLUSIÓN: Existe una relación directa, proporcional y significativa entre el PAN y los valores de Hb; sin embargo, aunque las gestantes anémicas presentaron con mayor frecuencia BPN, esta diferencia no fue significativa.

AIM: To link maternal anemia and birth weight (BW) in women with term pregnancies present to emergency obstetric at the Maternity "Dr. Armando Castillo Plaza", in Maracaibo, Venezuela. METHODS: A correlational research, with non-experimental and transactional design, where valued a sample of 200 pregnant women in active phase of labor, who are determined hemoglobin (Hb), hematocrit (Hct), and hematimetric indexes values. RESULTS: The values of Hb and Hct in anemic ranged from 8.4 ± 1 g/dl and 11.6 ± 0.64 g/dl, whereas the Hct was 28.8 ± 3.3% and 38.9 ± 2.2%, in patients with and without anemia, respectively. The hematimetric indexes showed normal reference values in both groups. The BW in newborn of anemic mothers was decreased by 12.39% (-420 g) when compared to the weights of infants of mother without anemia (2.970 ± 0.43 g vs. 3.390 ± 0.32 g; p<0.0001). LBW was more common in the group of anemic mothers, who showed an increased risk, although not significant (15% vs. 10%; OR 95%CI 1.588 [0,676-3,728]; p>0.05). Was demonstrated a directly proportional and significant relationship between Hb values and BW(r=0.439; p<0.0001). CONCLUSION: Exist a direct proportional and significant relationship between the PAN and the Hb; however, while anemic pregnant women presented more frequently LBW, this difference was not significant.

A Relapsing Case Of Guillain-Barre Syndrome (GBS)- With Full Term Pregnancy.

Abstracts: Guillain-Barré syndrome (GBS)-complicating pregnancy is rare with estimated incidence between 1.2 and 1.9cases per 100,000 people annually., and it is generally believed that it carries a high maternal and fetal risk. We reported a case of 25 year old3rdgrvida patient with relapse of predominantly motor GBS(affecting lower limb muscles) complicating pregnancy without history of antecedent infection. patient managed with IV corticosteroids and IVIG.Patient successfully delivered vaginaly with vaccume without any operative intervention with uneventful postpartum period.

Clinical efficacy and safety study on full-term pregnancy termination with misoprostol / 中国生化药物杂志

Objective To investigate clinical efficacy and safety of misoprostol for termination with full-term pregnancy.Methods The number who had terminations with full-term pregnancy in our hospital obstetrics from July 2013 to March 2014 were 78, divided them into the experimental and control groups.Experimental group used misoprostol for induction of labor, the control group used oxytocin for induction of labor.Indicators were observed and compared between two groups of pregnant women, induction of labor effect indicators: the success rate of induction of labor, postpartum hemorrhage in 2h, the time of labor and the time of fetal delivery, cesarean section rate; induction of labor safety indicators: maternal complications and side effects, the physiological condition of the newborns and Apgar score.Results Basic information was no significant different between the two groups of pregnant women.induction of labor of experimental group success rate was 97.44%, which was 82.05% in the control group, success rate in experimental group was higher than the control group, with statistically significant results (P0.05), the experimental group had one case of mild neonatal asphyxia, there are two cases in the control group and one case of mild asphyxia neonatal asphyxia.Conclusion Effect of misoprostol which is used to terminate the pregnancy term is significant, and has high security, has high clinical value.