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1.
Enferm. foco (Brasília) ; 15: 1-9, maio. 2024. ilus, tab
Article in English | LILACS, BDENF | ID: biblio-1553863

ABSTRACT

Objetivo: Mapear as teorias de enfermagem utilizadas nos diferentes contextos de assistência à criança e ao adolescente. Métodos: Revisão de escopo de acordo com a metodologia do Instituto Joanna Briggs, que incluiu estudos primários, publicados em inglês, espanhol e português, sem restrição de tempo, e disponibilizados nas bases de dados MEDLINE, WOS, BDENF, SCOPUS, CINAHL e SCIELO. Resultados: Foram incluídos nesta revisão 53 artigos, os quais evidenciaram 17 teorias de enfermagem aplicadas aos mais diversos contextos pediátricos, como hospitalização, terapia intensiva, cuidados para doenças crônicas e promoção da saúde. A teoria mais utilizada para direcionar o cuidado foi a Teoria da Adaptação de Roy. São várias as experiências exitosas no campo da pesquisa e prática assistencial com a utilização das teorias de enfermagem. Conclusão: Diferentes teorias de enfermagem embasam o cuidado de enfermagem pediátrica; e a escolha de cada teoria deve ser norteada por um propósito explícito ou assunto de interesse dos autores, com base em suas expectativas pessoais e nas evidências científicas. Por meio deste estudo foi possível vislumbrar o potencial de cada teoria para subsidiar a prática da enfermagem pediátrica. (AU)


Objective: To map the Nursing theories used in the different contexts of assistance to children and adolescents. Methods: Scoping review according to the Joanna Briggs Institute methodology and included primary studies, published in English, Spanish and Portuguese, with no time restrictions, and made available in the MEDLINE, WOS, BDENF, SCOPUS, CINAHL and SCIELO databases. Results: A total of 53 articles were included in this review, which evidenced 17 Nursing theories applied to the most varied pediatric contexts, such as hospitalization, intensive care, care for chronic conditions, and health promotion. The theory most used to direct care was the Roy's Adaptation Theory. There are several successful experiences in the field of research and care practice with the use of Nursing theories. Conclusion: Different Nursing theories support pediatric Nursing care; and the choice of each theory must be guided by an explicit purpose or subject of interest to the authors, based on their personal expectations and on the scientific evidence. Through this study it was possible to glimpse the potential of each theory to support pediatric Nursing practice. (AU)


Objetivo: Mapear las teorías de Enfermería utilizadas en los diferentes contextos de atención a la niñez y adolescencia. Métodos: Revisión de alcance según la metodología del Joanna Briggs Institute que incluyó estudios primarios, publicados en inglés, español y portugués, sin restricciones de tiempo, y disponibles en las bases de datos MEDLINE, WOS, BDENF, SCOPUS, CINAHL y SCIELO. Resultados: En esta revisión se incluyeron un total de 53 artículos, que evidenciaron 17 teorías de enfermería aplicadas a los más variados contextos pediátricos, como hospitalización, cuidados intensivos, cuidados de enfermedades crónicas y promoción de la salud. La teoría más utilizadas para dirigir el cuidado fue la Teoría de la Adaptación de Roy. Existen varias experiencias exitosas en el campo de la investigación y la práctica asistencial con el uso de las teorías de Enfermería. Conclusión: Diferentes teorías de Enfermería sustentan la atención de Enfermería pediátrica; y la elección de cada teoría debe estar guiada por un propósito explícito o tema de interés para los autores, con base en sus expectativas personales y en la evidencia científica.A través de este estudio se pudo vislumbrar el potencial de cada teoría para sustentar la práctica de la Enfermería pediátrica. (AU)


Subject(s)
Nursing Theory , Pediatric Nursing , Review Literature as Topic , Nursing Care
2.
Med. U.P.B ; 43(1): 84-93, ene.-jun. 2024. ilus
Article in Spanish | LILACS, COLNAL | ID: biblio-1531514

ABSTRACT

El diagnóstico de enfermedad de Parkinson (ED) se basa en las principales manifestaciones motoras: bradicinesia en combinación con temblor en reposo, rigidez o ambos. Cuando se realiza el diagnóstico basado en la sintomatología motora clínica típica ya se han perdido hasta el 60 % de las neuronas dopaminérgicas de la sustancia negra pars compacta mesencefálica. La identificación de los síntomas premotores son un marcador temprano para sospechar la aparición futura de la enfermedad, así como su progresión y gravedad. La hipótesis sobre la patogénesis que mejor expone la progresión de la enfermedad es la teoría de Braak. Esta se basa en la aparición y presencia de cuerpos de Lewy en diferentes estructuras anatómicas, las cuales representadas en cada uno de sus seis estadios y podrían ser la explicación biológica de los síntomas premotores, motores y no motores. La detección temprana de los síntomas premotores puede tener repercusiones positivas en el enfoque, seguimiento, diagnóstico y tratamiento de la EP. El propósito de este artículo es identificar las aproximaciones neurológicas descritas por la teoría de Braak para los síntomas premotores de la enfermedad de Parkinson de acuerdo con la literatura publicada en los últimos 20 años.


The diagnosis of Parkinson's disease (PD) is based on the main motor manifestations: bradykinesia in combination with tremor at rest, rigidity, or both. When the diagnosis is made based on typical clinical motor symptoms, up to 60 % of the dopaminergic neurons of the mesencephalic substantia nigra pars compacta have already been lost. The identification of premotor symptoms is an early marker to suspect the future appearance of the disease, as well as its progression and severity. The hypothesis about the pathogenesis that best exposes the progression of the disease is Braak's theory. It is based on the appearance and presence of Lewy bodies in different anatomical structures, which are represented in each of its six stages and could be the biological explanation biological of premotor, motor, and non-motor symptoms. Early detection of premotor symptoms can have positive repercussions in the approach, follow-up, diagnosis and treatment of PD. The purpose of this article is to identify the neurological approaches described by Braak's theory for the premotor symptoms of Parkinson's disease according to the literature published in the last 20 years.


O diagnóstico da doença de Parkinson (DP) baseia-se nas principais manifestações motoras: bradicinesia combinada com tremor de repouso, rigidez ou ambos. Quando o diagnóstico é feito com base em sintomas clínicos motores típicos, até 60% dos neurônios dopaminérgicos da substância negra pars compacta mesencefálica já foram perdidos. A identificação de sintomas pré-motores é um marcador precoce para suspeitar do futuro aparecimento da doença, bem como da sua progressão e gravidade. A hipótese sobre a patogênese que melhor expõe a progressão da doença é a teoria de Braak. Isto se baseia no aparecimento e presença de corpos de Lewy em diferentes estruturas anatômicas, que estão representados em cada uma de suas seis etapas e podem ser a explicação biológica dos sintomas pré-motores, motores e não motores. A detecção precoce de sintomas pré-motores pode repercutir positivamente na abordagem, acompanhamento, diagnóstico e tratamento da DP. O objetivo deste artigo é identificar as abordagens neurológicas descritas pela teoria de Braak para os sintomas pré-motores da doença de Parkinson de acordo com a literatura publicada nos últimos 20 anos.


Subject(s)
Humans , Adult , Middle Aged , Aged , Aged, 80 and over
3.
Chinese journal of integrative medicine ; (12): 62-74, 2024.
Article in English | WPRIM | ID: wpr-1010326

ABSTRACT

Elemene, derived from Curcuma wenyujin, one of the "8 famous genuine medicinal materials of Zhejiang province," exhibits remarkable antitumor activity. It has gained wide recognition in clinical practice for effectiveness on tumors. Dr. XIE Tian, introduced the innovative concept of "molecular compatibility theory" by combining Chinese medicine principles, specifically the "monarch, minister, assistant, and envoy" theory, with modern biomedical technology. This groundbreaking approach, along with a systematic analysis of Chinese medicine and modern biomedical knowledge, led to the development of elemene nanoliposome formulations. These novel formulations offer numerous advantages, including low toxicity, well-defined composition, synergistic effects on multiple targets, and excellent biocompatibility. Following the principles of the "molecular compatibility theory", further exploration of cancer treatment strategies and methods based on elemene was undertaken. This comprehensive review consolidates the current understanding of elemene's potential antitumor mechanisms, recent clinical investigations, advancements in drug delivery systems, and structural modifications. The ultimate goal of this review is to establish a solid theoretical foundation for researchers, empowering them to develop more effective antitumor drugs based on the principles of "molecular compatibility theory".


Subject(s)
Humans , Retrospective Studies , Antineoplastic Agents/therapeutic use , Neoplasms/drug therapy , Drugs, Chinese Herbal/therapeutic use , Sesquiterpenes/therapeutic use
4.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 211-217, 2024.
Article in Chinese | WPRIM | ID: wpr-1006573

ABSTRACT

Patients with cancer-related fatigue are prone to symptoms and signs such as anorexia, weight loss, and abdominal distension, which seriously reduces the quality of life and becomes an independent risk factor affecting the survival rate of patients with malignant tumors. Therefore, it is urgent to find effective treatment strategies and drugs. In the past, the academic viewpoint of improving syndromes—a new strategy for tumor treatment was proposed based on the guidance of the Luobing theory. Based on this, this article proposes the pathogenesis of cancer-related fatigue is characterized by spleen and kidney deficiency, stasis and toxin internal obstruction, as well as the treatment method of strengthening the spleen and tonifying the kidney, resolving blood stasis and detoxification guided by the core theory of the Qiluo doctrine of Chengzhi Tiaoping. The representative drug Yangzheng Xiaoji capsules has been developed, not only has good therapeutic effect on solid tumors, but also shows good advantages in treating cancer-related fatigue, which can help to restore the homeostasis of tumor bearing survival in patients with malignant tumors and provide new drug choices for the clinical treatment of cancer-related fatigue.

5.
Journal of Traditional Chinese Medicine ; (12): 121-127, 2024.
Article in Chinese | WPRIM | ID: wpr-1005358

ABSTRACT

There are different views on the theory of “spleen governs time”, which is still a hot spot in the study of Zangxiang (藏象) theory. Based on Zangxiang time-space view, it is found that the thinking mode of the spleen governing time theory follows space-time logic. It is believed that the different time views of the spleen governing time are all formed based on the space view that the spleen belongs to earth and resides in the center, and the zang time theory is developed with the unified time and space logic. Guided by Zangxiang time-space view, the origin of the spleen belonging to earth and residing in the center is traced, and the theoretical connotation and its clinical application of spleen governing time under different time-space logic are explored with reference to the four season and five zang theory, five season and five zang theory, six season and six zang theory, and eight season and eight zang theory.

6.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 198-208, 2024.
Article in Chinese | WPRIM | ID: wpr-1005270

ABSTRACT

IgA nephropathy is the most common primary glomerular disease in China. Its clinical manifestations are mainly proteinuria, hematuria, hypertension, edema, hyperuricemia, etc. Most patients have hidden onset. 30%-40% of patients develop into end stage renal disease 10-20 years after diagnosis and rely on dialysis or kidney transplantation to maintain their lives, which is extremely harmful. Proteinuria is a common clinical manifestation of this disease, and most patients have small-to-moderate amounts of proteinuria, while 10%-24% of patients have large amounts of proteinuria. Proteinuria is the main risk factor affecting the progression of renal function in IgA nephropathy. Podocytes are the terminal part of the glomerular filtration barrier, and various factors can affect the fusion and detachment of podocyte processes that occur after podocyte injury. They are common histological lesions in IgA nephropathy and are key factors leading to proteinuria and the continuous progression of the disease. At present, Western medicine lacks targeted treatment for podocyte injury, with limited intervention methods. Drugs such as glucocorticoids are often used for treatment, and there are many adverse reactions. Based on the physiological function of podocytes, pathological and physiological changes after injury, and histological morphology of this disease, it is believed that it is closely related to traditional Chinese medicine's "Xuanfu Theory" "Kidney Collateral Syndrome" "Collateral Disease Theory", and "Dry Blood Theory". More and more studies have shown that traditional Chinese medicine, which has the characteristics of multiple links, pathways, and targets, has a significant therapeutic effect on podocyte injury in IgA nephropathy. It can protect podocytes and reduce proteinuria and has good application and research prospects. This article systematically summarizes the mechanism and morphological changes of podocyte injury in IgA nephropathy, the understanding of podocyte injury in traditional Chinese medicine theory, and the research progress in traditional Chinese medicine treatment of podocyte injury in IgA nephropathy, so as to provide a reference for further research and application of traditional Chinese medicine intervention in podocyte injury in IgA nephropathy.

7.
Journal of Traditional Chinese Medicine ; (12): 6-12, 2024.
Article in Chinese | WPRIM | ID: wpr-1005104

ABSTRACT

The modernization of traditional Chinese medicine (TCM) theories is not only a prerequisite for the modernization of TCM but also a way to deal with the external environment and the difficulties of its development. The modernization of TCM is based on the premise of maintaining its own characteristics and advantages, and along with the progress of modern science and technology, the entire TCM has undergone new changes and improvements from theory to practice, and has become a scientific system with modern scientific level that adapts to the needs of the times. In the context of the unprecedented profound changes in contemporary TCM academics, this paper puts forward the definition of modernization of TCM theory and argues that the modernized theoretical system of TCM should maintain originality to build the foundation of TCM inheritance, clarify the frontier of the discipline and establish the conceptual system, form an open network to be compatible with multi-disciplinary interaction, incorporate the falsification and establish self-renewal system, creatively transform and innovatively develop, and modernize the interpretation and update the discourse system.

8.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 270-278, 2024.
Article in Chinese | WPRIM | ID: wpr-1003789

ABSTRACT

Fibrosis can occur in diverse tissue and organs and is the common outcome as multiple chronic diseases progress. It is characterized by over-activation of fibroblasts and excessive deposition of extracellular matrix. Targeting transforming growth factor-β (TGF-β), a classical signaling molecule in fibrosis, is currently a routine strategy for drug therapy of this disease. The use of traditional Chinese medicine (TCM) in the treatment of fibrotic diseases has been supported by mature theories. The theories emphasize that the internally-accumulated pathogens and mixed deficiency-excess underlie the shared pathology of fibrotic diseases. Qi stagnation, blood stasis, phlegm turbidity, and mass accumulation are key pathological factors. "Yin suppression by Yang" is the core thought for treatment with TCM of the disease. Pharmacological investigations reveal the scientific nature of TCM in treating fibrotic diseases, namely multilevelled and multitargeted. In other words, it refers to networked regulation of signaling activities of fibrosis-related molecules such as TGF-β/Drosophila protein homolog (Smad), phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt), Hedgehog, Wnt/β-catenin, and inflammatory cytokines, so as to inhibit fibroblast function and provide a promising insight into novel anti-fibrotic drug. This paper summarized the conventional understanding of fibrotic disease treatment with TCM and its mechanism of action by reviewing ancient literature and modern research reports, which offers an idea for follow-up research in this field.

9.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 178-186, 2024.
Article in Chinese | WPRIM | ID: wpr-1003780

ABSTRACT

Diabetic kidney disease (DKD) is the main cause of end-stage renal disease. Its high prevalence, mortality rate, and medical cost bring a heavy economic burden to society and families, and DKD has become one of the most important public health problems. Intestinal microecology is the most important and complex micro-ecosystem in the human body, which is involved in important life activities such as material and energy metabolism, immune system regulation, and signal transduction, thereby maintaining the dynamic balance of the human internal environment. The dynamic balance between the intestinal microecology and the body is essentially a Yin-Yang balance. Once this balance is broken, intestinal microbiota imbalance, intestinal mucosal barrier damage, immune dysfunction, and reduction of metabolite short-chain fatty acids (SCFAs) will occur, which play an important role in the progression of DKD. From the perspective of the Yin-Yang theory of traditional Chinese medicine (TCM), the imbalance of intestinal microecology in DKD is equivalent to the excessive or insufficient constraint of Yin and Yang, or Yin deficiency affecting Yang, or Yang deficiency affecting Yin, or waning and waxing of Yin and Yang. For different pathogenesis changes, "Yin disease treated through Yang", "treating Yin for Yang", or "treating Yang for Yin" methods are adopted to regulate intestinal microbiota, inhibit immune inflammation, protect intestinal mucosal barrier, and increase SCFAs through TCM, thereby reconciling Yin and Yang to achieve the condition where "Yin is at peace and Yang is compact". Based on the Yin-Yang theory, this paper intended to interpret the scientific connotation of TCM in the treatment of DKD with intestinal microecology as the target and TCM in the treatment of DKD by regulating intestinal microecology as the breakthrough point to provide a novel insight for the occurrence and development of DKD and the mechanism of TCM.

10.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 187-195, 2024.
Article in Chinese | WPRIM | ID: wpr-1016478

ABSTRACT

The term ''panvascular'' refers to the human vascular system, which is a complex network of arteries, veins, and lymphatic vessels. Panvascular diseases refer to a group of vascular system diseases, with vascular atherosclerosis as the common pathological feature. The panvascular diseases in target organs such as the heart, brain, kidney, and limbs are caused by ischemia or bleeding, including arterial system diseases, venous system diseases, microcirculation system diseases, and Zangfu organ-blood vessel diseases. The concept of panvascular diseases integrates vascular lesions and target organ damage. In clinical practice, blood vessels in multiple regions are regarded as a large vascular unit system, and vascular lesions and the induced target organ damage are considered as a whole. Based on the holistic concept and the Zangxiang theory in traditional Chinese medicine (TCM), the ''blood vessel-Zangfu organ-syndrome differentiation and treatment'' network is built, on the basis of which a pattern of vascular disease-Zangfu organ dysfunction-syndrome differentiation and treatment is applied to the TCM diagnosis and treatment of panvascular diseases. The theory of treating arterial system diseases from the heart, venous system diseases from the kidneys, and microvascular system diseases from the liver is proposed. According to the causes identified based on syndrome differentiation, this paper summarizes the methods of reinforcing Yang and activating blood (including warming Yang and activating blood, replenishing Qi and activating blood, replenishing Qi, nourishing Yin and activating blood, activating Yang and blood, dispersing cold and activating blood), cooling blood and resolving stasis, tonifying kidney and promoting urination coupled with activating blood and dredging vessels, nourishing Yin and tonifying kidney coupled with activating blood and dredging vessels, and soothing liver and regulating Qi coupled with activating blood and dredging collaterals, as well as wind-extinguishing medicines, applied to the treatment of panvascular diseases, aiming to provide methods and ideas for the treatment of vascular diseases with TCM.

11.
Chinese Medical Ethics ; (6): 475-478, 2024.
Article in Chinese | WPRIM | ID: wpr-1012924

ABSTRACT

On March 20, 2022, the General Office of the CPC Central Committee and the General Office of the State Council issued The Opinions on Strengthening Ethical Governance of Science and Technology, which put forward five ethical principles of science and technology: promoting human well-being, respecting the right to life, adhering to fairness and justice, reasonably controlling risks and maintaining openness and transparency. Ethical principles require to be studied and interpreted concretely by ethical scholars, that is, first, they need to be refined in order to be truly guided; second, the principle of balance is needed to truly guide; third, it is necessary to study ethical theory in order to truly guide; fourth, it is significant to explore Chinese civilization in order to truly guide. In this way, the ethical principles of science and technology can be practically applied and guide the concrete practice of science and technology.

12.
Chinese Medical Ethics ; (6): 206-210, 2024.
Article in Chinese | WPRIM | ID: wpr-1012877

ABSTRACT

In order to build a global community of health for all, it is necessary to deeply understand the influencing factors of cross-cultural communication between medical professionals and patients. Factors such as different health beliefs, cultural values and communication mediators influence cross-cultural communication between medical professionals and patients, and then affect the medical satisfaction and treatment compliance. Medical education should adopt the learning concept of constructivism, advocate maintaining a humble cultural attitude, incorporate more patient perspectives and adopt cross-cultural teaching mode to improve the cross-cultural communication competence of medical students and medical staff, so as to establish a relationship based on communication and understanding.

13.
Chinese Medical Ethics ; (6): 129-134, 2024.
Article in Chinese | WPRIM | ID: wpr-1012862

ABSTRACT

Taking the graduation ceremony of Peking University Health Science Center in 2020 as the observation object, this paper used Collins’ Interactive Ritual Chains Theory to analyze the form, theme and featured part of this ceremony from the dimensions of physical co-presence, barrier to outsiders, joint focus of attention and shared mood. It was found that the ceremony in medical colleges had an impact on the cognition, behavior and spirit of junior medical students in terms of group identity, emotional energy, group symbols and moral sense, which played a good role in professionalism education. Some enlightenment and thinking were obtained on this basis to provide some references for medical colleges to give full play to the educational function of the professionalism in the post-epidemic era.

14.
Malaysian Journal of Health Sciences ; : 1-11, 2024.
Article in English | WPRIM | ID: wpr-1011514

ABSTRACT

@#The phenomenon of depression has been a major concern recently, both nationally and globally. Depression is a disorder that involves changes in thoughts, emotions, feelings, and behaviours that make a person’s daily life difficult, and if left untreated, can adversely affect individuals and society. Depression among adolescents certainly deserves attention as this group is considered as an asset that will drive the country in the future. In terms of methodology, PubMed, Science direct, and Google Scholar search engines were used which focused on psychological theories related to adolescent depression. In addition, the search also focuses on Cognitive Approach or more precisely, about Cognitive Behaviour Theory (CBT). Over the past few decades, Cognitive Behaviour Theory (CBT) has been proven to be the most dominant theory in psychological studies including depression in adolescents. As a result, it is found that, under the CBT group, Learned Helplessness Theory and Beck’s Cognitive Behaviour Theory were the two most widely discussed on the concept of depression to date. Therefore, this article will discuss the background and the concept of these theories in describing depression. However, Beck’s CBT has been selected as the most appropriate theory in discussing depression in adolescents because this theory is able to explain this issue further and in detail, in addition to having an extensive amount of research showing the effectiveness of Beck’s CBT in helping adolescents with depression compared to Learned Helplessness Theory.

15.
Chinese Journal of Experimental Traditional Medical Formulae ; (24): 234-240, 2024.
Article in Chinese | WPRIM | ID: wpr-1011463

ABSTRACT

Refractory angina is characterized by recurrent and persistent angina with a duration of not less than three months, which is related to reversible ischemia and hypoxia caused by coronary stenosis and obstruction. It mainly involves obstructive coronary artery disease and non-obstructive coronary artery disease with coronary artery spasm and coronary microvascular dysfunction. “Stasis and toxin” play an important role in the pathogenesis of cardiovascular diseases. The pathogenesis of stasis and toxin is stubborn filthy turbidity featured by slow accumulation and sudden onset,and rapid changes,which coincides with the characteristics of refractory angina which is complex and changeable,prolonged and difficult to cure. The pathogenesis of refractory angina involves a combination of underlying deficiency and excessive manifestation, with "stasis and toxin" playing a crucial role as an important pathological factor in the whole process of refractory angina. Traditional Chinese medicine (TCM) employs a holistic approach known as "activating blood circulation and removing toxins", which is supplemented by various methods to tonify Qi and warm Yang, nourish the kidneys and invigorate the spleen, clear heat and transform phlegm. This approach applies anti-inflammatory measures, regulates lipid metabolism, inhibits oxidative stress and thrombus formation, protects endothelial function in blood vessels, as well as establishes collateral circulation for the prevention and treatment of refractory angina. Therefore,based on the theory of "stasis and toxin",combined with TCM theory and modern medical research,this paper discusses the pathogenesis of refractory angina and the prevention and treatment strategy of TCM,and elucidates the reasons for the difficulty in curing refractory angina and the relationship between refractory angina and common angina pectoris,coronary microvascular dysfunction,coronary artery spasm and obstructive coronary artery disease,hoping to provide certain theoretical basis and clinical ideas for the prevention and treatment of refractory angina with TCM.

16.
Chinese Herbal Medicines ; (4): 42-55, 2024.
Article in English | WPRIM | ID: wpr-1010755

ABSTRACT

The mild-natured and bitter-flavored traditional Chinese medicines (MB-TCMs) are an important class of TCMs that have been widely used in clinical practice and recognized as safe long-term treatments for chronic diseases. However, as an important class of TCMs, the panorama of pharmacological effects and the mechanisms of MB-TCMs have not been systemically reviewed. Compelling studies have shown that gut microbiota can mediate the therapeutic activity of TCMs and help to elucidate the core principles of TCM medicinal theory. In this systematic review, we found that MB-TCMs commonly participated in the modulation of metabolic syndrome, intestinal inflammation, nervous system disease and cardiovascular system disease in association with promoting the growth of beneficial bacteria Bacteroides, Akkermansia, Lactobacillus, Bifidobacterium, Roseburia as well as inhibiting the proliferation of harmful bacteria Helicobacter, Enterococcus, Desulfovibrio and Escherichia-Shigella. These alterations, correspondingly, enhance the generation of protective metabolites, mainly including short-chain fatty acids (SCFAs), bile acid (BAs), 5-hydroxytryptamine (5-HT), indole and gamma-aminobutyric acid (GABA), and inhibit the generation of harmful metabolites, such as proinflammatory factors trimethylamine oxide (TAMO) and lipopolysaccharide (LPS), to further exert multiplicative effects for the maintenance of human health through several different signaling pathways. Altogether, this present review has attempted to comprehensively summarize the relationship between MB-TCMs and gut microbiota by establishing the TCMs-gut microbiota-metabolite-signaling pathway-diseases axis, which may provide new insight into the study of TCM medicinal theories and their clinical applications.

17.
Psicol. USP ; 35: e220050, 2024.
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1550634

ABSTRACT

Resumo A atuação de Donald Trump durante o período em que esteve na presidência dos Estados Unidos suscita a investigação de possíveis semelhanças entre ele e líderes fascistas do passado. A proposta deste ensaio é apresentar reflexões sobre a atuação política de Trump, inspiradas pelas discussões sobre a psicologia e a propaganda fascista na teoria crítica. Embora pareça impossível tomar Trump por um líder fascista clássico, principalmente em razão de contextos históricos muito diferentes, também é impossível desconsiderar o nexo entre suas estratégias políticas e o modus operandi de agitadores fascistas no século XX. Além disso, é inegável que sua política mobiliza elementos sociopsicológicos que remontam às análises da emergência do fascismo histórico, como a identificação com uma figura idealizada e transcendente, a submissão a uma autoridade ou causa superior e a agressividade direcionada às ameaças do out-group.


Abstract Donald Trump's actions during his presidency calls for an investigation regarding possible similarities between him and fascist leaders of the past. This essay is reflects on Trump's political actions inspired by discussions on fascist psychology and propaganda within Critical Theory. Although Trump may escape the category of a classic fascist leader, mainly due to the different historical contexts, the similarities between his political strategies and those of 20th-century fascist agitators is undeniable. Moreover, his politics mobilize socio-psychological elements that date back to the emergence of historical fascism, such as identification with an idealized and transcendent identity, submission to a superior authority or cause, and aggressiveness directed to out-group threats.


Resumen La actuación de Donald Trump durante el período en el que fue presidente de los Estados Unidos plantea la posibilidad de investigar posibles similitudes entre los líderes fascistas del pasado y él. El propósito de este ensayo es presentar reflexiones sobre la actuación política de Trump inspiradas en discusiones sobre psicología y propaganda fascista en teoría crítica. Si bien parece imposible ver a Trump como un líder fascista clásico, principalmente debido a contextos históricos muy diferentes, también es imposible ignorar el nexo entre sus estrategias políticas y el modus operandi de los agitadores fascistas en el siglo XX. Además, es innegable que su política moviliza elementos sociopsicológicos que se remontan al análisis del surgimiento del fascismo histórico, como la identificación con una identidad idealizada y trascendente, la sumisión a una autoridad o causa superior, y agresividad dirigida a amenazas del out-group.


Résumé Les actions de Donald Trump au cours de sa présidence appellent une enquête sur les similitudes possibles entre lui et les leaders fascistes du passé. Cet essai réfléchit aux actions politiques de Trump en s'inspirant des discussions sur la psychologie et la propagande fasciste au sein de la Théorie Critique. Bien que Trump puisse échapper à la catégorie de leader fasciste classique, principalement en raison de contextes historiques très différents, les similitudes entre ses stratégies politiques et celles des agitateurs fascistes du XXe siècle sont indéniable. En outre, sa politique mobilise des éléments socio-psychologiques qui remontent à l'émergence du fascisme historique, tels que l'identification à une identité idéalisée et transcendante, la soumission à une autorité ou à une cause supérieure, et l'agressivité dirigées vers les menaces du out-group.


Subject(s)
Humans , Male , Aged , Fascism/history , Critical Theory , Mass Behavior , Psychology, Social , Communism
18.
Rev. latinoam. enferm. (Online) ; 32: e4095, 2024. graf
Article in English | LILACS, BDENF | ID: biblio-1530195

ABSTRACT

Objective: to understand the meaning attributed by men to the experience of caring for their family member with cancer and to develop a substantive theory that represents the experience of men caring for their family member with cancer. Method: this is qualitative research guided by the methodological framework of Grounded Theory and the precepts of Symbolic Interactionism. A form with identification and interview data was used. The analysis followed the substantive and theoretical coding stages. Results: 12 male caregivers of their family member with cancer participated. The constant comparative analysis of the data allowed the creation of a substantive theory "Experiencing the care of a family member with cancer: men as a caregivers" explaining the experience that has as its central category "The love that drives care", representing the symbolic actions and attitudes of men living in the context of illness due to cancer and care Conclusion: the theory allowed us to understand feelings, perceptions, ways of acting and facing the diagnosis, providing care, recognizing difficulties and learning from the situations that arise, making explicit the interactional processes and symbolic elements present and how these influence male caregivers in their actions and attitudes.


Objetivo: comprender el significado atribuido por los hombres a la experiencia de asistir a un familiar con cáncer y desarrollar una teoría sustantiva que represente la experiencia de los hombres acerca de dicho cuidado. Método: se trata de una investigación cualitativa guiada por el marco metodológico de la Teoría Fundamentada y los preceptos del Interaccionismo Simbólico. Se utilizó un formulario con datos de identificación y entrevista. El análisis siguió las etapas de codificación sustantiva y teórica. Resultados: participaron 12 hombres cuidadores de un familiar con cáncer. El constante análisis comparativo de los datos permitió elaborar una teoría sustantiva "Vivenciando el cuidado de un familiar con cáncer: el hombre como cuidador" explicando la experiencia que tiene como categoría central "El amor que impulsa el cuidado", representando la acciones y actitudes simbólicas del hombre que vive en el contexto de enfermedad por cáncer y sus cuidados. Conclusión: la teoría permitió comprender los sentimientos, percepciones, formas de actuar y afrontar el diagnóstico, brindar cuidados, reconocer dificultades y aprender de las situaciones que se presentan, explicitando los procesos de interacción y elementos simbólicos presentes y cómo influyen en los hombres cuidadores en sus acciones y actitudes.


Objetivo: apreender o significado atribuído pelos homens à vivência do cuidado ao seu familiar com câncer e elaborar uma teoria substantiva que represente a vivência de homens no cuidado ao seu familiar com câncer. Método: trata-se de uma pesquisa qualitativa norteada pelo referencial metodológico da Teoria Fundamentado nos Dados e pelos preceitos do Interacionismo Simbólico. Utilizouse formulário com dados de identificação e entrevista. A análise seguiu as etapas de codificação substantiva e teórica. Resultados: participaram 12 homens cuidadores de seu familiar com câncer. A análise comparativa constante dos dados permitiu a elaboração de uma teoria substantiva "Vivenciando o cuidado de um familiar com câncer: o homem como cuidador" explicativa da vivência que tem como categoria central "O amor que conduz o cuidar", representando as ações e atitudes simbólicas do homem ao viver no contexto do adoecimento por câncer e do cuidado. Conclusão: a teoria permitiu conhecer os sentimentos, percepções, modos de agir e enfrentar o diagnóstico, desempenhar o cuidado, reconhecer as dificuldades e aprender com as situações que se apresentam, deixando explícito os processos interacionais e os elementos simbólicos presentes e como estes influenciam os homens cuidadores em suas ações e atitudes.


Subject(s)
Humans , Male , Caregivers , Grounded Theory , Symbolic Interactionism , Neoplasms/therapy
19.
Horiz. enferm ; (Número especial: Investigación y práctica en condiciones crónicas de salud): 193-207, 2024. ilus
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1553525

ABSTRACT

El cáncer es una de las principales causas de mortalidad en la niñez y la adolescencia. Tanto el impacto biopsicosocial y espiritual que produce, puede llevar al niño a experimentar dolor y sufrimiento. OBJETIVO: Comprender aspectos comunes percibidos por la enfermera oncológica y como se relacionan en la valoración de un niño con dolor. MÉTODO: se trató de un estudio cualitativo con diseño de teoría fundamentada de datos según referencial metodológico de Strauss y Corbin. Por medio de muestreo teórico fueron seleccionados 13 participantes profesionales de enfermería pertenecientes a diferentes hospitales de Santiago de Chile. Los datos fueron recolectados a través de entrevistas semiestructuradas y en profundidad. El estudio se rigió por medio de los criterios de credibilidad, confirmabilidad y fidelidad de Guba y Lincoln. Los datos recolectados fueron transcritos posterior a cada entrevista y analizados en tres etapas: codificación abierta, axial y selectiva. RESULTADOS: para las enfermeras que trabajan en el área de oncología infantil, es central el cuidado entregado en el proceso de enfermedad del niño hospitalizado por cáncer, considerando aspectos como el perfil de las profesionales, las emociones, la capacitación, las reacciones frente a un niño con dolor y las relaciones que existe entre ellos. CONCLUSIONES: Existen aspectos que resultan común en las enfermeras que se desempeñan en oncología infantil y que producto de las relaciones existentes entre ellos, pueden inclinar a las profesionales a reconocer el dolor en los niños con cáncer desde diversas perspectivas.


Cancer is one of the main causes of mortality in childhood and adolescence. Both the biopsychosocial and spiritual impact it produces can lead the patient child to experience pain and suffering. OBJETIVE: To understand common aspects perceived by the oncology nurse and how they are related to the assessment of a child in pain. METHOD: We conducted a qualitative study with a grounded theory approach based on Strauss and Corbin's methodological framework. Through theoretical sampling, 13 nursing professionals who worked in different hospitals in Santiago, Chile were selected. Data collection took place through semi-structured, in-depth interviews. The study followed Guba and Lincoln's criteria for credibility, confirmability, and fidelity. The data collected was transcribed after each interview and analyzed in three stages: open, axial and selective coding. RESULTS: For nurses who work in pediatric oncology, the care provided throughout the illness process for the child is central, considering aspects such as the profile of the professionals, the emotions, training, reactions to a child in pain, and the relationship that exist amongst them. CONCLUSIONS: There are common aspects amongst nurses who work in pediatric oncology. Because of the relationships between them, these aspects can help professionals to recognize pain in children with cancer following diverse perspectives.

20.
Horiz. enferm ; (Número especial: Investigación y práctica en condiciones crónicas de salud): 429-442, 2024.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1553598

ABSTRACT

INTRODUCCIÓN: El automanejo y el cambio de conducta siguen siendo retos para quienes padecen enfermedades crónicas. Para su abordaje existen modelos y estrategias que orientan a alcanzar mejores resultados en salud. OBJETIVO: Analizar la Teoría del Automanejo Individual y Familiar junto con el Modelo Transteórico como paradigmas para comprender los desafíos e identificar factores involucrados en el cambio conductual y el automanejo de personas con enfermedades crónicas. DESARROLLO: El Modelo Transteórico comprende cinco etapas que explican el proceso cíclico de cambio. Por otro lado, la Teoría del Automanejo Individual y Familiar se distingue por tres dimensiones: contexto, proceso y resultados. Al interrelacionar ambos modelos, se observa que el contexto dado por la Teoría del Automanejo Individual y Familiar puede determinar la etapa del cambio. Los procesos, como la autoeficacia, la facilitación social o la autorregulación, son implementados de formas distintas según la etapa del cambio en la que la persona se encuentre. CONCLUSIÓN: La integración de ambos modelos potencia la comprensión acerca del cambio de conducta en personas con enfermedades crónicas. Esta articulación favorece enfoques más personalizados, lo que permitiría que los profesionales de enfermería reconocer la etapa de cambio en la que se encuentra la persona y, con base en la Teoría del Automanejo, atender las necesidades del individuo y familia, propiciando un cuidado integral.


INTRODUCTION: Self-management and behavioral change continue to be challenges for those suffering from chronic diseases. There are models and strategies for approaching them that aim to achieve better health outcomes. OBJECTIVE: Analyze the Individual and Family Self-Management Theory together with the Transtheoretical Model as paradigms to understand the challenges and identify factors involved in behavioral change and self-management of people with chronic diseases. DEVELOPMENT: The Transtheoretical Model comprises five stages that explain the cyclical process of change. On the other hand, the Individual and Family Self-Management Theory is distinguished by three dimensions: context, process and outcomes. By interrelating both models, it is observed that the context given by the Individual and Family Self-Management Theory can determine the stage of change. Processes, such as self-efficacy, social facilitation or self-regulation, are implemented in different ways depending on the stage of change the person is in. Finally, outcomes, such as self-management, emerge from the effective joint application of both models. CONCLUSION: The integration of both models enhances the understanding of behavior change in people with chronic diseases. This articulation favors more personalized approaches, which would allow nursing professionals to recognize the stage of change in which the person is and, based on the Self-Management Theory, address the needs of the individual and family, promoting comprehensive care.

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