ABSTRACT
Venous thromboembolism (VTE) is a common perioperative complication in patients with thoracic malignant tumor. Once it occurs, it will not only affect the prognosis of patients, but also occupy a lot of medical resources, which is gradually causing our widespread attention. However, the understanding of VTE in thoracic surgery in our country is relatively late, and the recognition and attention are not enough, and there is still a lack of guidance support for perioperative VTE. Based on the current understanding and preventive measures of VTE in thoracic surgery in China, The China National Research Collaborative Group released the first edition of Chinese experts consensus on the perioperative VTE prophylaxis in 2018. This article will interpret the high-risk patients with perioperative VTE in patients with thoracic malignant tumors, in order to provide a better understanding of Chinese experts consensus for readers.
ABSTRACT
The risk of perioperative venous thromboembolism (VTE) is pretty high in thoracic cancer patients. Perioperative VTE influences the recovery of patients after operation and quality of life in the future, even seriously leading to death. To strengthen the knowledge and attention of thoracic surgeons on perioperative VTE in thoracic cancer patients, China National Research Collaborative Group on VTE in Thoracic Surgery released the edition of VTE prophalaxis in thoracic cancer patients: Chinese experts consensus in 2018. This article is to interpret the diagnostic value and risk prediction value of D-dimer in VTE in detail, and briefly introduce the role of other biomarkers in VTE of tumor patients. The consensus interpretation aims to deepen the understanding of thoracic surgeons on the clinical significance of D-dimer in VTE.
ABSTRACT
Objective To investigate the effects of desflurane on cardiac troponin I (cTnI) and myocardial enzyme. Methods Thirty ASA Ⅰ~Ⅱpatients scheduled for selective operation were randomly divided into three groups of tenin each: Desflurane group(D group), Isoflurane group(I group) and Enflurane group(E group). Anesthesia was maintained with inhalation of 1.0MAC of desflurane, isoflurane, and enflurane in each group respectively. Blood samples were taken before anesthesia, 1 h after inhalation and at the end of inhalation for the determination of plasma cTnI, CK, CK-MB, AST and LDH activities. Results cTnI, AST, LDH, CK and CK-MB levels were normal before anesthesia. At the end of inhalation, CK increased significantly in three groups, CK-MB increased markedly in Enflurane group and Isoflurane group, but CK-MB level was normal in desflurane group. However, the CK-MB level was normal in all patients. cTnI, AST, LDH showed little changes during inhalation. Conclusions Inhalation of 1.0 MAC of desflurane, isoflurane and enflurane doesn't result in myocardial injury.